posted Tue, 10/11/2016 - 04:53
1166
Igf 1 supplement effect on HGH dosing
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I've found multiple articles on Igf 1 supplementing and it's effect on be able to lower your HGH dose. The reason being a lot of the action HGH creates is due to its effect which causes the liver to release Igf 1. this creates the theory that you can use less HGH when you supplement Igf1 and stretch your HGH. So my question is, for those of you who supplement exogenous Igf1, how much do you decrease your HGH dose by. Or is this a bs theory?
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There is actually a synergistic interaction between GH and IGF1 (Somedin), of course for the same net effect one may reduce the GH dosage if using IGF1 with it and get the same results, but I would actually recommend to keep GH dosage as high as your budget allows you with some IGF1
It's true that the IGF1 is the mediator for most of the anabolic effect of the GH, but we must consider 2 things -
The GH has some direct metabolic effect by itself, both in releasing glucose and fatty acid into the circulation, and by this raising metabolism and releasing available energy for anabolic demands, The GH has also a direct effect on nitrogen balance not through the IGF1 path, so it's wise to keep GH dosage as high as one may afford
The IGF1 itself has a direct suppressing effect on the endogenous GH release - so if u inject exogenous IGF you actually and directly suppress any GH present in the circulation
Further more - many GH users are not aware to the fact that GH decreases insulin sensitivity. IGF1 increases insulin sensitivity, and negates this effect, which leads to optimal metabolic conditions. Some users use insulin in conjunction with GH but using IGF1 is much more effective in retaining optimum insulin sensitivity and much much safer
or just eh opposite way, you can use the same HGH en less IGF1, it depends of the goals you have. I have using 10ui of GH per day and 50mcgr of IGF1. Before i was using 80-100mcgr of IGF1, without GH. I am preparing for a competition
It makes sense to me but I have not tried it. I'm currently running 5iu a day of hgh (yellow ang). I just started my first cycle of adding in the igf-1 last week. I'm interested to see what others think on this topic.