kylekyle1989's picture
kylekyle1989
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glutamine stops GYM PUMPS!

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hey guys

i have herd down the great vine that glutamine actully stops u from getting full pumps during trainning if u take it in ur prework out shake ???
what are ur guys thoughts ?

thekaz's picture

http://jpet.aspetjournals.org/content/281/1/448.short

The article posted in the link above is titled : "Glutamine Inhibits Nitric Oxide Synthesis in Bovine Venular Endothelial Cells"

From the abstract I will post the key parts : The addition of l-glutamine (0.5 and 2 mM) markedly increased intracellular concentrations of l-glutamine, l-glutamate andl-aspartate and decreased NO synthesis by EC in a concentration-dependent manner in the presence or absence of A23187, bradykinin or substance P

In other words, when they introduced L-glutamine into the experiment, it decreased NO synthesis. The research went further to state that L-glutamine didn't have a negative effect on L-Arganine uptake, and the process involved in decreasing NO synthesis remained unknown after concluding the experiment.

Also in 2004, another study showed that L-glutamine inhibits vascular nitric oxide (NO) production in vitro. (ScienceDirect.com)

...regardless of that i think it works just fine

HydeMind's picture

Interesting!

thekaz's picture

thanks bro just tryina contribute. i KNOW what the science says, but i still like glutamine. I don't take it for the pumps anyways, I take it for the recovery. If you want something for pumps try AAKG and some caffeine. Your veins will be pumping out of your body

HydeMind's picture

I've been taking glutamine for years before and after workouts never had a negative impact on my muscule pumps. Glutamine is great, great for muscle recovery and it is used as fuel for the immune system so it's important for us gym rats to supplement.

kylekyle1989's picture

yeah i thought that cant be possible my self also!
but keept hearning people say it so thought i might see what use all thought

IbkillinEm's picture

Sgt I thought you quit working out anyways and just run a 1g/week deca only cycle year around..that's the word going round the "great vine" anyways.. Lol, my brother

IbkillinEm's picture

Lol! Killer cycle bro!

hypnoso's picture

I just dont believe that. I take glutamine all day basically and still get great pumps. SOmetimes on some orals too good of pumps. But I dont think there is any research behind that.