+ 34 Why I don't use Tren anymore, and never will again
The dogs in the street know that Tren is a psycho.
Sure, there are outliers who can eat it all day long without suffering the way you or I do, but they are few and far between. When I was young, I could use it at high doses without getting crazy, and I did, for years on and off. But it has taken it's toll on my mind, along with other things. Now I suffer all of the sterotypical sides, moreso with tren a due to its high peak, but also with tren e. From heyday high doses, I now cannot even handle 100mg Tren E pw without succumbing to high BP, flipped lipids, and cognitive annihilation. You name it; my bird is a cnut, the world is a wanker, and I will smash your jaw around the back of your filthy head etc. etc. Disgusting really.
Some of you will remember the study from about 3 years back, many wont, and lot's wont care. But, you should.
Some very smart chappies out of China's Shandong University studied rats to see what Tren was doing in the brain. Now before you cry foul of the poor little rats, remember that their endo system is more or less the same as ours. Mammals are good like that, generally speaking.
Anyway; they discovered that beta amyloid plaques were accumulating in a very significant way in the brain. They realised it was plaque 42 which the brain doctors firmly accuse of being a leading cause of Alzheimer's Disease.
Shiiiiiiit..... right?
Yeah but the die hard won't give a crap and sure we have all been there at some point. But, the study went further. It actually figure out that it is the standard mediation of effects via the androgen receptor that caused it. They also realised there is significant neuronal damage taking place..... wait for it......it KILLS brain cells too....
OH FUCK!
So after years of the strength gains, the slow muscle building gains, and the fat burning magic of tren
I realise something isn't right. MY brain does not work the way it did before. There are many factors for that, but when it is really off it feels the way it does on tren (the sterotypical bad effects). So... anecdotally speaking, damage has been done.
So, I cannot handle it, but it also kills brain cells and is gradually potentially causing Alzheimer's.
I'm out...... for good
There is hope though
Alzheiner's is an area where there is massive scientific interest and significant investment. Recent studies showing new proteins can clear the plaques and prevent more from forming. You might also want to take a look at this study, courtesy of Carlos Danger: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169155. This is far more accessible than the protein which is very far from being realised as any sort of treatment.
So, it's up to you, as always.
What you do is your own business and some of us are adults here on eroids too! But for me, even though there is hope down the line for some of the damage tren causes, I dont want to end up in a position where I have already forgotten about it! I also don't want to keep killing brain cells, nor do I want to feel the cognitive destruction that tren causes anymore. It accumulates with time, and retrospectively I can swear to you that it is not worth it.
References
http://www.ergo-log.com/trenbolone-may-increase-alzheimer-s-risk.html - I have the full study, if anyone wants to read it, it is eye opening, I can email it to your anon email addey, just PM me.
https://www.sciencealert.com/new-protein-injection-reverses-alzheimer-s-...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169155
EDITS
Edited to add the following link from Carlos Danger: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169155
Edited to add, from BJ: Mineral volcanic water for Alzheimer’s: https://pubmed.ncbi.nlm.nih.gov/22976072/
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After seeing my 23 and me results. having the gene related to late onset alzheimer's I have one more reason to pass. I also lucked out and scored the celiac gene and both the hemochromatosis genes.
Same here . https://www.promethease.com
Its good to be informed. Hopefully I don't develop the Alzheimer's or hemochromatosis .
Already have the celiac.
Yea, the Alzheimers elevated risk was my only level 3 warning so I am not overly concerned. I need to live that long first,lol. To my surprise I don't have many cardiac risk markers and with my family history I assumed I would.
Great to have such a range of knowledge, to make a truly informed decision.
Does use of AAS effect your Iron levels Burrr?
No iron from gear, but I had to cut back on fortified cereal.
Also quit using cast iron cookware.
I've had high ferritin levels on some bloodwork years ago, but when I addressed my celiac disease it dropped down.
Ok so presumably, a somewhat higher rbc/hemo level doesnt necessarily uptake more iron unless it is provided? Is that fair to say?
Thats really interesting. I had no idea the cookware could make a difference. That is amazing.
Not from my experience.
My high ferritin was a result of the inflammatory response of celiac.
My ferritin levels and iron saturation are in range now.
I do get some elevated RBC on cycle, but not bad, especially considering I live at high altitude.
Yeah I can remember living in Colorado many years back... always up Pikes Peak etc.
When I got back home this side of the water, I felt as if I could run forever.
I would say my blood would turn to tar overnight if I went back now!
Glad your all in range etc. sounds good now.
I probably won’t ever run it myself again. I’d seen the links to Alzheimer’s a year or so ago, and decided it wasn’t for me. I watched a grandmother go through all that. We weren’t real close, but if I can avoid it, that’s not how I want my kids to see me go
I had a few great runs on it, and a pretty fucked up run or two, and I realize I can accomplish anything I really want to do without it. There are some much less harsh alternatives that provide some amazing results, and it’s pretty easy to shed fat if you’re shooting for 350-400 grams of protein on a chicken and fish diet. But now is beef season...
Appreciate the post. Definitely a great read, and just confirms what my mind has been telling me about it for awhile now.
I thibnk I remember chatting to you about it in a forum back then a year or so ago shawn.
Yeah when you witness the worst possible outcome of that type of damage, it makes it very real when you are talking about.... well.... doing it on purpose.
Respect.
Very eye opening. Love all your research.
Really the only tren I use now is injectable mtren for prep. Tren really doesn't seem to provide me much benefit if any at all over the other compounds I use so it is just not worth the side effects for me to run a cycle of it, with the exception of the inj mtren for a about a 2-3 wk period. Brain damage is definitely one side effect I would like to avoid.
Right back at you man. Very much so
Yeah the contest prep seems to really be an area where more serious guys like yourself take benefits and really weight the risk v reward (I cannot see any real justification outside of your type of BB'er), But you raise a really interesting point... when you look to the entire combo, food, training, AAS, discipline etc.... there is no major reason to use it necessarily. You can achieve the building with other AAS, the fat loss with clever diet manipulation etc. But importantly those things can be done without the crazy downsides.
Tren is a dance with the devil and we all know it. She will sweet talk you in, then make you crazy and ravage your insides.
Couldn't have said it better Pale. Honestly, that sums it up.
"I now cannot even handle 100mg Tren E pw without succumbing to high BP, flipped lipids."
About 4 years ago I ran Tren A for about 8 weeks - I didn't like it - just made me a c*nt (or more of one maybe) and I didn't feel that I got much else out of it. Last year I ran a long cycle of Test 125mg pw and Tren E 200mg pw. I found that the moodiness/aggression was easier to control on the E. I made some good gains, got a lot of vascularity and strength. Two months after coming of it I was back in hospital with a 2D Echo-cardiogram result showing that I was slightly worse off than when I was in ICU the previous year. The only thing that I can think of that would have turned me from having a reasonably good functioning heart to being a basket case again was the Tren and possibly the strain of training heavy. That's the thing that Tren did to me - it 'encouraged' me to lift heavy if you get what I mean - I went against my Docs orders because I felt fucking strong and wanted to lift heavy.
I'm with you mate - will never touch the stuff again....great, informative post from you as always. +1
Well the training definitely does cause an issue at some level, no doubt, but the tren would definitely accelerate anything that crops up. Sorry to hear that Oz.
This is the thing, it clearly affects the frontal cortex in the brain, and thats where our exec decisions are made from. So, in the face of clear and good advice we go against it. Maybe part ego, part desire.... but all tren??
Never again man.
Exogenous testosterone is causing early brain cell death, too. However, calcium channel blockers were shown in rat or mice brain cells to negate the effect. Funny, having treatment for high blood pressure may actually be saving my brains. The debates continues, though.
Once we get outside of homeostasis, in general, we seem to break down pretty god damned quick.
I lost a part of my brain. It wasn't the end, though at the time it certainly felt that way. Better living through psychopharmacology and endocrinology in combination with a will forged from iron made a new homeostasis and a different, stronger person.
Really? What happened man?
On screen, you seem utterly focused, crystal clear and articulate well.
By the way, thanks for the compliment. No homo!
LOL - yes no homo of course!!
I am fully focused, and even when I was losing my pituitary to a tumor I was focused, which in a way made things worse because I knew something was wrong and couldn't change for the better while feeling my life had already run its course at just 34 years old. 10 years of a living death. Now I am a cocktail of prescriptions designed to replace and enhance the damaged remains. In a way, I am grateful for what happened as I doubt I would have become so driven. I am a savage and only just civil enough.
Oh my god man, I am sorry to hear that now, really.
But, I am inspired by how you have overcome it.
I respect that a hell of a lot. We could all learn from you.
I get what you mean. Gotta keep building, breaking down sucks.
I'm sure running numerous cycles of any compound over the years cannot be good for the brain and mental clarity. Test, Dbol, Anadrol. Masteron even EQ all cause you to think and feel differently so one way or another must have an impact on brain activity eventually.
Test is actually essential to the proper function of the frontal cortex. You are right, though, but I doubt it is more harmful than training which includes getting punch in head. I love boxing, and I haven't given it up, either.
Hey man if thats what you enjoy doing then keep it up - plus the extreme physical fitness levels required to do that for 12 rounds is nothing but good for you. Unbeleiveable how fit boxers have to be, never realised until I started to look into it all. Was it Norvasc out of interest they gave you for the high BP?
The endurance is what drew me to boxing, the sweet science would be hard to quit. I received training from a fighter who had 150 wins, about 100 of them were by KO. He was 73, and move like a 30 year old. He gave me a black eye for dropping my guard. Learned so much from him. Anyways, I was given Lercanidipine as a calcium channel blocker.
The fittest people in the world are those who came up through the amateur boxing ranks. Second to none if you ask me.
This is super cool to me. I just got hired in a lab that models protein expression by analyzing tertiary structures and formation. I may get assigned to amyloid beta peptide but there are others were working on. They’re looking into how it’s structure is formed and how it leads to aggregation. Eventually into how to prevent, stop, or reverse it. I don’t think my supervisor would like to kno I kno about trenbolone tho lol. Maybe keep this is my back pocket for my masters
Why keep it in your back pocket? Research is about bringing new knowledge to whatever field of endeavour is concerned. Take the idea to your supervisor as something that you have recognised is becoming a general topic of discussion across a broad range of forums and might be a worthwhile thesis topic. A thesis is supposed to contribute to the sum total of human knowledge - so it is encouraged in academia to pursue topics that have not been explored before..
I’d like to get a feel for the place a bit better before I suggest bringing in a controlled substance for experimentation. I’m not even sure this lab has correct lockbox for controlled substances since it’s in a whole different class of hazards than biological ones.
But in the future I could have a solid reputation and access to a lab with the right security and ask permission to use it. Since there is a linkage between amyloid beta and tren depending on what my supervisor thinks they may be open to asking the DEA for future research.
Dude, +'s!
There is a serious idea in there for a thesis!
very very informative read giardap !! thanks brother !!
but as for my self I wont lie I wont stop using ..is it wise or good for my health probably not ! the only downside from tren for me is acid reflux ,night sweats and loss of breath ...its no walk in the park but I managed to handle them ! I hope somewhere in the near future my addiction to tren stops and take more serious my health above gains !! this should be a sticky especially for youngsters who want to be mr o in 10 weeks !! + a million if I could
Tell me dude - do you find any food past mildly spicy a complete no go on tren? ..
tbh I dont have a tinny problem with spicy foods just the extra sweat ...It get serius with fish yogurt sweat potato....and iam not allergic to something it happens only when I use tren !!
RustyhookerNo carbs 4hrs pre bedtime and nightsweats get eliminated. Tren is a carb whore...use those carbs in your favor ;)
yeah your right on rusty !!
I enjoy the night sweats, they make me laugh waking up soaking! Its the acid reflux that does my head in...
RustyhookerThe acid burps pukey gunk....ya thats the nasty one i hate
yeah I dont mind them neither but wifey hate me for that lol !!
Never thought of that - must be awful for partners to be waking up in a load of bodybuilders cold sweat haha at first they must wonder what on earth is going on?!
I used to play the old; "I think I am coming down with something honey, sniffle sniffle"... but after the 4th or 5th month she got suspicious
Wel this is it man. We are all our own person, at the end of the day. But at least now you have the info if that day comes when your perspective changes. Information / knowledge = power
I knew couple of nasty things that tren does not the usual tren sides the more serius ones ,but thanks to you brother and your digging I have the clear picture about it !!
no worries man.
Man I feel tren ruined a couple good relationships for me that could have lasted forever.. Amazing woman but tren just messed with my head. I would think stuff was happening that wasnt, I would get jealous. Always think people are plotting on me or something. Would get anxiety sometimes too.. I feel it may have messed with my brain a little memory wise, but I smoke nug so no telling haha. Tbh I would never run Tren again but I'm sure I will 4 weeks out from shows because nothing works like it unfortunately :(
Yeah it really sees to be a staple for that final month. Well me too, same as you, I ruined 1 relationship and almost did with my current. Thankfully my woman is the best and she is way more resillient than me, whilst taking none of my sh!t.