just wanted to throw this out there. One of our sources sent me this a few weeks back when started having estro issues while running a low dose of aro
http://www.ironmagazineforums.com/anabolic-zone/180274-exemestane-underd...

Aromasin is suicidal, like it has been stated, and it also becomes stronger the more you use it. Because its suicidal, u can crash estro easily which will NOT come back unless u use higher doses of real HGH, and if u don't have that then u have to wait 1-3 wks for your body to produce more Aromatase. If u crash your Aromastase enzymes even 100mg dbol daily won't spike your estro u Tim Aromatase is circulating through your body again. Taking aromasin EOD is fine as is ED, you have to find what works for you because everyone's reaction to aromasin is slightly different. Personally, 10mg EOD is plenty enough for me. Aromasin is a very interesting drug I just wish it didn't cause so much hairloss for me lol

Careful how you interpret this study. Remember the selected age group were males ages 14-26...which are males at their peak levels of testosterone. Most of us are pumping our bodies full of test. Taking Aro with higher test showed a lower estradiol level being suppressed with both group 1 and 2.

JCEM has some of this listed right on the study on paragraph 3 of the discussion section;

The maximal suppression evoked by exemestane at the single dose of 25 mg in the present study was similar to published results in postmenopausal women, but the time course differed (24). Evans et al. (24) reported that a single 25-mg oral dose of exemestane maximally suppressed estradiol concentrations by 72% 3 d after administration, and estradiol levels returned to baseline only 8–11 d after drug administration. In the present study maximal suppression of estradiol of 62% was observed 12 h after exemestane administration and returned to baseline 3–6 d after administration. The reason for this difference is not clear, but may be related to the shorter half-life of exemestane in males, the lower exposure to exemestane, and the higher levels of the aromatase substrates androstenedione (∼1 ng/ml in young males vs. ∼0.5 ng/ml in postmenopausal women), particularly the much higher testosterone concentrations in young males than in postmenopausal women (∼700 ng/dl vs. ∼20 ng/dl, respectively) (25). This is supported by the observation that in the 10-d study in young males reported here, the suppression of estradiol is weaker (due to the very high levels of the precursor testosterone) than that of estrone (due to androstenedione levels not very different from those in postmenopausal women). A limited suppression of circulating estradiol (∼50%) has been reported in a similar study in young males treated with 1 mg daily anastrozole (7), a dose that reduces estradiol by 85% in postmenopausal women (23).

TAKE Aromasin Once daily in the AM.
That what is already known in medical use!

With the half-life in males of 8 - 9 hours, I'm now thinking to divide my daily dose into 3 doses and take it every 8 hours - 7 AM, 3 PM, and 11 PM. Thanks for the info!

i notice it says the terminal half life at being 8.9 hours , with a maximum of 12. definitely changes how ill use aro from now on. good read good find. thank you.