gqelite's picture
gqelite
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Elevated estro from hcg?

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I started taking hcg 500iu x2 week. Doctors office called and said that my estrogen was 59. Waiting on paper work to post. Is this something I should worry about or can I let it drop as I discontinue taking hcg? Thanks

MedDx's picture

When the drug is discontinued, your level will drop. Why are u taking hcg? 19-nor?

Doss's picture

There's more benefits with hcg supplementation than just what's called for with 19-nors. Every compound shuts you down. 19's are just harder on the axis. Regardless, hcg promotes a balanced, healthy axis during periods of shutdown, whether prolonged or otherwise.

To the OP:

Hcg will always raise estro levels. Your AI dose should increase when using it. You weren't using it for pct were you?

gqelite's picture

I was. The entire order of pct I had received was bunk. Thanks.

Doss's picture

Hcg during pct does not help you recover. It's an exogenous hormone and exhibits negative feed back on the hypothalamus and pituitary.

PoundForPound's picture

I've read some interesting stuff recently
by Michael Scally M.D.
His practice is totally devoted to PCT and other circumstances to rescue hypogonadism. He says that there is not one study which shows a negative feedback, or desensitization to endogenous GnRH hormones caused by hCG extant.
He has a program called Power PCT which entails the usual stuff--Clomid, Nolva, Ai--but also 2,500iu of hCG EOD for 16 days. He's also a bodybuilder who does these regimens himself.
I'm not taking one side or the other, but it's pretty interesting...

Doss's picture

First off, hcg does not correlate with GnRH nor does it stimulate its release. It simply mimics the hormone LH. As far as his statements on lack of neg feedback, all I can tell you is that the proof is in the bloodwork. Try it for yourself and don't believe everything you read.

PoundForPound's picture

Easy pal, I know everything you said. First off, don't play semantics; I know what hCG does. Most don't know that it's a mimicker so for ease of discussion, I used that term--GnRH. Try it myself? Oh yeah, anecdotal evidence is reliable, huh? And try what, triggering a down regulation of receptors? Lol!
Secondly, don't assume I haven't done hCG but that means nothing in terms of the thoughts which I tried to share with you because I thought they were interesting.

Doss's picture

No one is playing semantics brother, and don't get so defensive. You can interpret my statement however you choose, but I was in no way insinuating or suggesting to attempt a down regulation. What I suggested was to run bloodwork while administering hcg and see the results for yourself. But to attempt to use terms like GnRH and gonadatropic hormones interchangibly not only confuses the average reader but is misleading. Try to choose your words more carefully in this sort of thing bc there are too many newbs floating around that misinterpret or get led astray.

PoundForPound's picture

Fair enough.
You're right: I'd be the first to point out the importance of accuracy in such discussions but it pissed me off to have it done to me--grouchy old fucker that I can be.
Thanks

gqelite's picture

Right on. I thought it only surppressed when used for extended periods or in high doses. If you could pm me a more effective way I could have taken care of this I would appreciate it.

Doss's picture

Any exogenous hormone suppresses natty release of the same hormone. Hcg mimic LH so the body perceives it as being present. Hcg blasts prior to pct is beneficial for a prolonged, hard shutdown bc it helps shock the leydig cells in the testis to become revived. Then after the blast, your clomid and nolva stimulates the hypothalamus and pituitary to produce and release again.

Hcg during pct sends negative feedback.

PoundForPound's picture

That is definitely basic to
Physiology--homeostatic mechanisms.
I have a life science degree with heavy emphasis on physiology but it was 20 years ago. I do remember there being exceptions to that mechanism and I wonder if we can sometimes get so used to repeating these truisms that we may miss new evidence, or not have ever seen evidence for those truisms in the first place, we just impute everything with generalities we've learned with good intentions?
Again, I am by no means claiming that you're weong, I just want to study it further in light of what Dr Scally says.
Thanks!

gqelite's picture

Thank you. Yes. Disregarded all information here and ran one anyway. My entire pct wound up being bunk as well. So I was extremely shut down plus estro rebound was insane. Not fun.