OptimusWhey's picture
OptimusWhey
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aromasin vs arimidex

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im a bit confused, but is arimidex better in some way then aromasin for a basic test e cycle? because i see most people posting arimidex with there test-e cycle

tombo24's picture

how long is it healthy to stay on adex 1mg?anyone know a good source for aromasin want to give it a try

Carlos Danger's picture

It's probably not safe to be on 1mg adex period. Let alone for any length of time. .25mg eod is the preferred dose and even .5mg eod is plenty.

Carlos Danger's picture

Adex can unbind from the Aromatase enzyme once the drug is discontinued. Aromasin on the other hand binds to it permanently(Suicidal). Also Aromasin is by far better at controlling E2 which is the estrogen we as users want to control. Adex is also much harsher on lipids. Any user must already know that AAS will cause an increase in cholesterol. Well you should also know that Adex will increase it as well. That's something that concerns me but as long as you are on top of things with frequent blood tests checking lipids than it can be managed decently. It falls back to what our preference is and what we are used to. Aromatase Inhibitors come in 2 types. Type 1 and Type 2. First Type 1 AI's bind by a process called hydroxylation; this hydroxylation process produces an unbreakable covalent bond between the inhibitor and the enzyme protein. Now the enzyme is permanently blocked even after all of the inhibitor is removed and can only be resumed by new enzyme synthesis. Type 2 Inhibitors on the other hand function all the same in their ability to reduce the binding process of the enzyme and the receptor. Except once the drug is discontinued or the concentration of the drug is sparse enough it is possible for the enzyme to seperate itself from the Inhibitor and eventually will allow renewed competion between the Inhibitor and the Enzyme for the receptor site. Aromasin is a type 1 AI and once it does what it's purpose is we don't need to continue use. Letro and Adex are Type 2 Ai's and the success of those drugs are continigent on the Doses and protocol of which we use them. Once you stop them you expose yourself to an Estrogen rebound. Now having said all of that there are also many other reason to why Aromasin use is beneficial to a Bodybuilder. One is Arimidex/Anastrozole Decreases IGF-1 18% while Aromasin/Exemestane Increases IGF-1 28%. Another is Aromasin is also known to decrease estrogen between 90-95% while boosting Endogenous Testosterone by about 60%, and also help out your free to bound testosterone ratio by lowering levels of Sex Hormone Binding Globulin (SHBG), by about 20% (12)…SHBG is that nasty enzyme that binds to testosterone and renders it useless for building muscle
Here's a good link:
http://www.ironmagazineforums.com/anabolic-zone/125128-there-have-been-m...

Carlos Danger's picture

Glad to set some shit straight for u. I don't go back and forth on what you should use. Unless you are allergic to Aromasin there really is no comparison IMO.

DBG's picture

GS throwing down!! Nice read!!

Undertaker's picture

Nice read.

UKM's picture

Is it best to have both on hand at the start of your first cycle then just incase you don't respond to one?

DBG's picture

I remember reading something Perses wrote awhile back about how HIS body doesn't respond well to Aromasin, and he prefers Adex...and ever since then I have been in a CONSTANT battle with myself about which AI to use!!..lol.

I'll tell you this though...I have used Adex before and my estro levels were a problem, and that's why I am going with Aromasin this time around. Seek and destroy, LOL!!!

DBG's picture

Honestly..I have been REALLY bad about blood tests, so much so that I am not even going to mention it all! However, this time around...I am getting one pre, during, and post...no doubt. I have some other tests I am gonna have to get done like a thyroid panel too...but that's for something else, lol.

I am going for my post-PCT bloods next week...and HOPEFULLY I can start this run here soon after that...I was hoping by Oct. 28th. Everything seems to 'feel' good, but of course you can't just go with your gut for definitive reasons. I feel that my estro levels still might be a lil' high...it's weird to explain, but I can DEFINITELY feel my natty test levels are back...it's funny I get more RAGE when my natty levels kick in as opposed to when I am running gear. When I am on-cycle, really nothing in the world pisses me off...just the exact opposite OFF-cycle. Is this awkward or is this possible and do others have this condition too???

DBG's picture

So...that's what is causing my off-cycle attitude...higher than acceptable estro? Shit...I hope not, and then find out it's off the charts when I get my bloods.

Tell you something personal though...ya know what, I'll save it for PM...I don't wanna put myself out there like that on an open forum, plus I wanna stop cloggin up this thread, lol.

DBG's picture

OK...I'll PM ya later. I gotta go do something right now, lol!! I am sure you will be ON later...

I'm not an addict...LMAO!!!

mjunkie's picture

aromasin is stronger, u dont want to lower your E too much