posted Thu, 08/16/2012 - 08:46
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Arimidex vs aromasin
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Whats the difference between the 2 and what do you guys prefer?
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Whats the difference between the 2 and what do you guys prefer?
JohnnyBlackJust made the switch from adex to aromasin and never looking back. Made the switch while on cycle because i was feeling completely out of whack, sex drive sucked, had estrogen related sides up the yingyang, less than a week after making the switch its night and day.. literally feels like the beginning of my cycle i feel great!
good stuff right here thanks !
I can recommend a reputable pharmacy (Arimidex) http://mexselect.com/products/arimidex.htm?id=kulakgm I received the order and it was on time and the pills work great.
Mike no source promoting on the open forums.
cdaddy7Aromasin junkie. I used arimidex in the past and it just didn't work for me. Everybody is different in the way there bodies responds to compounds and that's y there is such varieties of med that are in the same class both take different receptor pathways to basically do the same thing. Arimidex has the better argument with the binding and cholesterol but if it don't work for u it doesn't really matter? That's y we have to learn our bodies and in cases like aromasin vs arimidex u have to use them both to find which one works for you the best. If you went to your dr and he out u on something and it wasn't workn then he would switch u. The same in this case. Does that make sense?
This answered a few questions for me! I suppose its not critical to have both on hand, but would be a good Idea. Somthing to digest
I have just finished my cycle, and I had to swap from Adex to Aromasin as I was getting gyno. high doses of Adex where not doing anything. It was my first cycle in 15 years and also the first time I was using an AI, as in the past I always went with Nolva. So I was quite dissapointed when I got the estro signs using Adex. The problem is that I will not know if my Adex was bunk or it's simply not for me (like your case). Unless I spend money on lab testing I guess I will never know. Anyway, as the Aromasin did its job and after reading more on it(thanks for your recent posts) I will be an Exemestante-Aromasin guy from now on.
Arimidex - drugs-store-online.com Good price and quality.
cdaddy7Glad I could help you in that. As more research comes out on Aromasin I think you got the pick of the litter on the AI. Keep your eye open for more good stuff including the Aromasin in the mix real soon ;)
Anonthis is easy fucking question. arimidex rebounds and aromasin doesnt. one is suicide tyoe ai other isnt aromasin all the way for me.
I had this booked marked for my self hope it helps, Anastrozole
Arimidex (Anastrozole) is what we call an aromatase inhibitor (AI). In clinical use, it8217;s used to halt the progression of Breast Cancer in women. It works by blocking the aromatase enzyme, which is responsible for the production of estrogen. In athletics and bodybuilding, it is used as an ancillary compound to be added to a cycle of Anabolic Steroids. In this respect it is also used for its estrogen reducing properties, but it has the additional benefit of increasing testosterone levels, as we8217;ll see...
Arimidex Side Effects
Many anabolic steroids aromatize (convert to estrogen via the aromatase enzyme), and this is responsible for many of the unwanted side effects found with anabolic steroid use (acne, gynocomastia, water-retention, etc...). In one study, both .5mg and 1mg doses of Arimidex were shown to decrease estrogen by roughly 50%. The 1mg/day dose also increased testosterone levels by 58% (1). In that same study, in both groups, LH and FSH also went up slightly.
Changes in testosterone and E2 concentrations in normal young men (15 22 yr old) before () and after 10 days of oral Anastrozole at 0.5 and 1 mg.(1)
This would seem to suggest that for use during a cycle, a dose of .5mgs/day would be sufficient to combat estrogen-related side effects. It is, however, important to remember that some estrogen is necessary to obtain optimal muscle growth. The lower estrogen levels provided by ´dex seems, anecdotally at least, to produce a more "hard" and "quality" look for bodybuilders who have experimented with it***8217;s use in either a cutting or bulking cycle.
I´d like to point out that the elevation in Testosterone provided by Arimidex is so large that it can be used as a "form" of testosterone replacement therapy for hypogonadal men (2). Clearly, this suggests its use in a post-cycle-therapy (as well as its previously discussed use within a cycle) to regain natural testosterone levels and full functioning of the HPTA (Hypothalamic-Testicular-Pituitary-Axis).
Literature provided by the original maker of Anastrozole (Arimidex, produced by Zeneca Pharmaceuticals) states that stable blood plasma concentrations of the compound are achieved after a mere 7 consecutive 1mg daily doses. Also, Arimidex is just over 80% effective at inhibiting aromatase (3). Thus, if you want to take it for the entire duration of a cycle of anabolic steroids, you can simply start taking it on the same day you begin your cycle. Those are some pretty good numbers, huh?
But can you use it for the entire duration of a cycle? Is it dangerous? Well, certainly reducing estrogen levels in your body is good from a body building point of view, as it reduces water-retention and the potential for gynocomastia (if there8217;s no estrogen in your body, you can8217;t get gyno, regardless of how much progesterone is floating around)(5). Luckily this stuff is very mild on blood lipids (cholesterol) and doesn8217;t affect them adversely (2), in the studies I8217;ve seen.
Arimidex and Cholestrol
As previously mentioned, those lowered estrogen levels could possibly (eventually) adversely affect your cholesterol and possibly even your immune function. I am, however, very comfortable recommending Arimidex for relatively long-term use. This should be the ancillary compound of choice for those on long and heavy cycles, especially since it also doesn***8217;t inhibit igf like some other ancillary compounds (insulin-like-growth-factor is an important component of anabolism)(4).
Aromasin
Exemestane
Aromasin (Exemestane) is a steroidal suicide aromatase inhibitor, which means that it lowers estrogen production in the body by blocking the aromatase enzyme, the enzyme responsible for estrogen systemization. (1)(2)(3)
This stuff was developed to fight breast cancer in post-menopausal women, who need a particularly aggressive therapy, and for whom first line defenses such as SERMS (Tamoxifen) have not worked. This should be our first clue in inferring that this stuff is pretty strong, or at least stronger than some of the other compounds which are used to fight breast cancer.
Aromasin and Side Effects
Aromasin averages an 85% rate of estrogen suppression (4), so it8217;s clearly a very effective agent for bodybuilders and other athletes wanting to avoid estrogen related side effects such as gyno, acne, or water-retention brought on by aromatizing steroids. Specifically, Exemestane dose this by selectively inhibiting aromatase activity in a time-dependent and irreversible manner (hence the "suicidal" portion of it8217;s name, I guess).(7)
As with most of the compounds in this class, it also causes a reasonable rise in testosterone levels (6), and as you may have guessed, this rise in testosterone means that Exemestane can also cause androgenic sides(8)(9)(10). Exemestane is very effective at both lowering estrogen (estradiol) and raising testosterone:
Estrogen and androgen plasma levels after 10 d of daily exemestane (25 or 50 mg) in healthy young males (mean ± SD; n = 9-11). To convert to System International units: estradiol, Pico moles per liter (x3.671); estrone, picomoles per liter (x3.699); androstenedione, nanomoles per liter (*0.003492); and testosterone, nanomoles per liter (x0.03467). (13)
So we can see that 25mgs is a very effective dose from that chart, right? As an added benefit, exemestane not only increases testosterone and lowers estrogen, but it also increases IGF levels (11).Additionally Worth noting is that Aromasin may possibly be less harsh on blood lipids (14)than some of the other (similar) compounds we use in the world of bodybuilding or athletics (other AI´s). It also has, at best no effect on IGF, and at worst could lower (13) it. AI´s are very tricky with regards to inconsistencies in IGF levels.
Unfortunately, you need to take Exemestane for a week to reach steady blood plasma levels of it, and exemestane has a ½ life of 27 hours (12.).
The ability of exemestane to lower estrogen levels by the aforementioned 85% makes it a very nice choice for use in any cycle where aromatizing steroids are used. In addition, since it8217;s not too harsh at all on blood lipid profiles, it8217;s a very good choice for longer cycles. It***8217;s ability to raise both testosterone levels also seem to suggest that it would be a very nice addition to a Post-Cycle-Therapy (PCT).
Well I guess I'll be the only one to say Aromasin/Extremasane is a more effecient AI. The difference is this, Adex can unbind from the Aromatase enzyme once the drug is discontinued. Aromasin on the other hand binds to it permanently(Suicidal). Also Aromasin is by far better at controlling E2 which is the estrogen we as users want to control. Adex is also much harsher on lipids. Any user must already know that AAS will cause an increase in cholesterol. Well you should also know that Adex will increase it as well. That's something that concerns me but as long as you are on top of things with frequent blood tests checking lipids than it can be managed decently. Aromasin is known to increase IGF-1 while Adex decreases it. It falls back to what our preference is and what we are used to.
Here's a good link:
http://www.ironmagazineforums.com/anabolic-zone/125128-there-have-been-m...
what do you mean by binds permanantly? you wont ever need AI again bec it will be permanantly there? can you explain?
Not exactly brotha I wish! So what a suicidal AI does is binds itself to the Aromatase Enzyme for the life of the enzyme, or until ur body wastes it. Even after the discontinued use of the medication. Meaning that enzyme will not be able to shake the AI and attach itself to a receptor after the drug is no longer in ur system. Arimidex works very well although once it has been discontinued the enzyme finds itself free of the AI and will serch out some receptors to attach itself to. Causing a possible estrogen rebound. Normally this happens at PCT time.
Very interesting. I enjoyed reading this post.
zewiBOOM!!!
so i guess the aromasin sounds like the better of the 2
Each drug reacts differently in everybody. While I love Aromasin there's a guy recently who posted that he felt horrible almost sick from the Aromasin. And others love Adex and it made me dry out so bad I lost energy and my joints and skin got so dry it sucked. So truly them both and see which ur body likes best.
so what would be a good dose on a Test Prop, Tren cycle. According to the article it says 25mg a day but i was advised 6.25 E3d. Much appreciated =)
I think the reason u were advised that was to establish a bare minimum or baseline of what dose ur body will react positively to. Always start low. Which I completely agree with. If I on the other hand were to run that dose would be covered in acne within 3 wk and so bloated I'd look all moonfaced. Dosages are different for everybody exactly like AAS doses are different for everybody. Hit me up with a FR and we can talk about this more thru PM. I don't want to jack someone else's thread brudda:-) hit me up
coo, sent you a PM
zewithere we go.. see gs i was waiting for you cause i no you love this PCt stuff. +1 from me brother.
Yessir! Honestly bro I enjoy the PCT/OCT aspect more than AAS. The good ol Adex vs Aromasin debate:-) I love it!
cdaddy7Another +1 from me brother. Nice post
Aromsin doesn't have the estro rebound like adex. Both used correctly are good
I personaly would always go with adex. I'm sure there is some good aromasin out there, but I've just heard of too many people having trouble with high estro levels while running it. It's a much newer drug than adex so it's more expensive and probably faked a lot more. I think you also have to consume a fatty meal with it for it to work properly. Some one correct me if I'm wrong, because I've never used aromasin.
zewiX2 a +1 from me..
Thanks bro!:)..... I see u took out the kitty avi, much better. Lol
zewi....