+ 20 Lets STOP the BRO SCIENCE
Before Let me tell you about my education Im a RN
I graduated from one of the top 20 Nursing school in America. An RN education includes Anatomy and physiology, Pathophysiology which this includes we learned in well detail about the endocrine system. Im writing this to stop the misconception of HCG.
Alot of forums and bobybuilders believe that HCG creates a negative feedback to the male hypothalamic pituitary gonadal axis and this is totally FALSE
HCG mimic LH and in NO WAY SHAPE OR FORM DOES LH CREATE A NEGATIVE FEEDBACK LOOP
Only Testosterone, DHT and Estrogens(Estrodoil and Oestrodoil) have a and inhibiting affect)

As you see in this image LH does not have anything to do with negative feedback loops and estrogens have a strong affect .This is why Nolvadex and clomid work so well and help us during PCT.

And we need AI because once the body see that there enough or alot of Estrogens it creates a negative feedback loop

Therefore thats why Aromasin is a wiser choice but Arimidex can work just as good only down fall is a slight rebound of short time burst of excessive E2(estrodoil)

This study below here backs up everything im typing
http://m.eje-online.org/content/155/4/513.short
This study below explains that HCG preserves our natural test production during and after exogenus Testosterone
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1478834/?page=1
So in conclusion HCG taken with and Ai to control aromatazation and in addition with Clomid and Nolvadex will make a strong PCT to regain our endogenous Testosterone production.
Now if u inject HCG alone with no Ai yes it will create a negative feedback loop because of the aromatization NOT HCG itself!!!
But i must add that we must also think about cortisol control during pct i will make another post about cortisol control during pct ive done it during my pct and i barley shrink. I only loose water weight and maybe an 1/8 inch in bicep circumference.
Anyways until next time
Happy eating Eroiders 
UPDATE: Thanx for the added knowledge of Numbhere we had a big debate and I learned that HCG suppress LH instantly http://www.ncbi.nlm.nih.gov/m/pubmed/19170708/
And suppress FSH after chronic use in the study below it took 3month for FSH to be suppreesed by HCG
BOTH FSH and LH are products of GnRH
That being said HCG does not stop GnRH instantly the 1st and most important step of the negative feedback loop. So clomid amd
Nolvadex will counter act this mechanism
http://www.ncbi.nlm.nih.gov/m/pubmed/3084535/
Also the longer we use HCG the more desentistization will occur to the LH receptors affecting the results of your PCT time
Using HCG during cycle which can be 10-15week has its pro and bigger con
Pro preserves testicular function Con Desentistize the LH receptors therefore come PCT time while clomid and nolvadex produces LH the LH will have no effect to the receptors therefore affecting Testostorone production by the testicles
If HCg used during PCT its used for a short period of time 4-5 weeks causing less desensitization and Clomid and Nolvadex will be used counteracting the LH suppression HCG can cause.
So in conclusion use this info and you decide how you wana take your ride either way we are still fucking our system up just one more than the other
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An RN education includes learning the endocrine system and endocrine disorders
We are kinda like mini doctors
So does high school human physiology. You're not a mini doctor, you're a nurse.
Tell that to the other RN in eroids
Well if they claim to be a mini doctor I will give them the same response.
You criticized me for posting the last study. However, not all the participants were given nandrolone. Yet, all had their LH suppressed from hcg.
I clicked on it and it requires a medscape login
That's odd because I don't have a medscape account and wasn't prompted for a login.
In that case thank you for posting the study so others can read for themselves.
hey man nice post!
Question for ya!
Let's say I forgot to take a PCT for example after just a Test cycle...
and it's a year later.
In order to raise natural test, fsh and LH levels, would both Nolva and Clomid be recommended. Or just Clomid since you weren't just on cycle.
Thanks!
First you should have blood work to confirm your levels, pre and post PCT. Without BW you're just guessing.If you haven't fully recovered then you should run a 4 week PCT of nolva and clomid.
Harley-DavidsonSo would you consider your standard eroids protocol of a pct regime to be best ?? Also what would be considered a good dose for hcg for this proper pct protocol ?? How often ?? And how many shots total ?? Appreciate the information regardless !! thank you !!
Clomid- 100mg/100mg/50mg/50mg
Nolv- 40mg/40mg/20mg/20mg
thats pct is world wide standard, not just eroids, its tried and tested, they are serms.
FR sent PM me
GearofWarNow THIS^^^is how karma is earned my brothers. Fantastic job and +1 from this guy. I'd give ya more if I could. Keep up the anti-bullshit posts and keep educating the uneducated!
Thank you you made LvL1 now wtf does that mean lol
Do i make more muscle gains per cycle now that iam LvL1?
Now you can give and take 1 karma point. Use it wisely!
Wish i could give u some karma. This is perfect
Give me merchandise LOL hahaha
Nice thorough explanation.getpump99 +2
Thank you MegaT883 love the mighty mouse avatar btw
getingbiginteresting post thanks
No problem fellow eroider just tryin to help
It will indirectly interfere with the hpta feedback loop. It will cause a raise in test which some will convert to e2 which will bind to the e2 receptors in the hypothalamus which as you pointed out is the STOP mechanism for the hpta and test production.
Oops my miss take u said HPTA not HTPA
Yes thats another name directly aiming at males (HP Testicular Axis)
HTPA are hormones like cortisol and norepinephrine, epinephrine and adrenal androgens
Bros confuse HTPA and HPGA all the time
But dont worry this post is to educate and stop all the confusement
In addition you are mentioning the HTPA -Hypothalamic–pituitary–adrenal axis
This includes other hormones
in AAS use we worry about the HPGA-Hypothalamic–pituitary–gonadal axis
Sir please re read my post thats why i said you must not take it alone
If you take it with clomid and nolvadex they cover the estrogen receptors confusing the body to belive there is bo estrogens present
And the Ai will prevent E2 accumilating
That's cool that you didn't sleep through class and all but back to the bro science... If you take hcg with test (preferably a prop taper ime) and then follow with a solid nolva/clomid or torem/clomid PCT, you get your shit back... Just to keep it simple for the lesser inclined in the pathophysiology of the LH and FSH function. ;)
Good post, bro. +1
We all love Bro Science <3
This is clearly directed at me lol. Well let me be the first to say you have clearly presented a strong argument to my previous statement, and I'm man enough to admit when I'm wrong. You clearly put a lot of effort into this post. Two more questions however:
1) The HcG study is from 1991, has any more informatiok come foward pertaining to it?
2) what's your stance on desensitization of the leydig cells due to Hcg overuse?
+2
LoL no it wasn't you just reminded how many times I've read it in the internet.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1478834/?page=3
On this study as linked above page 75 Biological Action at cellular level 3rd paragraph talks about receptor affinity and degradation
Yes the study is old but the simple fact that LH doesnt have a negative feedback loop still pertains to current text books as hcg mimic LH this fact will stay true
If you search other hcg studies the only thing hcg does mildly supress is FSH
But as MedDx stated clomid n nolvadex will overcome that problem
Thats why it's important not to take hcg alone
These compunds work synergisticly
Thanks for the studies bro. Once again, fantastic job, keep stuff like this coming!
Yea fosho when i have time ima talk about Testosterone:Cortisol ratio during the critical weeks of PCT
Good post, nice effort.
Hcg helps with Lh but what helps boost ur FSh ??
ArmedhMG
https://www.ncbi.nlm.nih.gov/pubmed/8263139
"hMG-hCG induced spermatogenesis after 24 months, with normal motility and quality"
Thanks!!
Gnrh too I believe, triptorelin (spell check)
Hard to find real triptorelin tho?
Even if u did the dosage needed is high
Nolva helps FSH...clomid helps LH and some FSH..
Actually they both raise LH and FSH but Nolva is more potent. 20mg of Nolva is equivalent to 150mg of clomid in raising LH and FSH in this study
http://www.ncbi.nlm.nih.gov/pubmed/640052
http://www.ncbi.nlm.nih.gov/pubmed/6128318
I live by NCBI its like the bible to life
Thank u sir =)