Uncommon Chemistry
And I'm barely functioning.
Started a moderate Primo cycle. 4th cycle, first time with Primo.
The facts:
Middle-aged, high aromatizer. My TRT clinic and an external consult both said they've never seen this before - bizarre to them, even.
Baseline (TRT 150mg + HCG 750 IU weekly CDG+DIM (to manage E2)):
Total T: 1100 ng/dL | E2: 46 pg/mL
Week 6 on cycle (Test 350mg, Primo 260mg, HCG 1000 IU weekly):
Total T: >1500 | E2: 27 pg/mL → a 60% drop!!
Test:E2 ratio: 65:1 (target 21–35:1)
How I feel:
Extreme lethargy, zero motivation, depression. Missing gym days I never would've skipped.
Backstory (for context):
Previous cycle (500mg Test + Dbol, no HCG): E2 was 102, felt incredible.
TRT alone (190mg Test + HCG): Test 985, E2 73, felt destroyed.
Same high E2, completely different results. No idea why.
Current plan:
Drop Test from 350 to 300, keep Primo and HCG the same for a few weeks.
Looking for input:
My consults agree the "backward" ratio (more Test than Primo) makes sense for me - but they're out of ideas.
Has anyone else experienced this? What worked for you?
Otherwise I'm honestly considering tapering off. This is crushing.
- Bookmark
- 0
- 0
Following up just to close this out.
10 days with test at 300 / Primo at 200 (weekly)
Dbol at 20mg daily
has me back in good shape.
Bump test to 600 and 300 primo (100mg 3x a week) and add in growth bro. You would see way better results with just test + hgh then test + primo
unseen423I'm trying to understand the question as well.
Sounds to me like Primo is not a compound that agrees with you. Why not go back to what worked and made you feel good (500 Test +Dbol, no hcg)? I know everyone swears Primo is God's gift, but maybe try something else like Masteron? Maybe DHB?
You might be right. I chose Primo over Dbol for health reasons (lipids, liver) at my age. Now I'm stuck with a cabinet full of something my body may not be able to adapt to. I'm trying to save the cycle and not waste the funds but this isn't working clearly.
So your question is why is your E2 crushed currently? Not being a smartass, just not fully understanding what the question is here?
Fair question. A few things I'm trying to figure out:
Why is my E2 crushed by 61% on only 260mg Primo? I know Primo has mild AI effects, but this seems extreme.
Has anyone else experienced being a high aromatizer and struggling to find a stable Free T:E2 ratio on moderate doses, while feeling great on high androgen loads (500mg Test + Dbol)?
How could I course correct my current cycle?
My plan is to drop Test to 300mg and cut HCG for a few weeks, but I'm open to other ideas.
unseen423Primo affects people differently. Some can take huge doses and some its a crazy AI effect at 100mg. It hit me pretty hard around 250mg, not to the point I felt bad, but it cut my E2 by 50%
Good to know I'm not alone, it sounds like Primo hit you similarly at 250mg. I'm convinced my issue is less the E2 number itself and more the Free T:E2 ratio being totally out of whack.
I hadn't considered running Dbol again, but with how much E2 headroom I have right now, maybe low dose Dbol (10-15mg) could raise E2 just enough to balance the ratio and salvage the cycle.
I don't know anything about running those 3 as a stack.
I'm a weekend warrior, not a bodybuilder. Any input?