HGH Gynecomastia Fact versus Fiction
What’s up everybody.
I’ll cut right to it. About three years ago I did an HGH cycle to treat chronic pain. Within days I noticed pain in the nipple area which lasted for a few weeks corresponding with unsightly enlargement of the breast. I more or less dealt with it for three years. I took raloxifene for 9 months with little noticeable result. The condition has continued until the present day. This week I went in for a mammogram to get a better understanding of the tissue. Lo and behold, no breast tissue showed up and so I don’t have gynecomastia technically speaking although obvious man boobs that I never dealt with prior to taking HGH.
Maybe the raloxifene absorbed all the breast tissue? In any case, it appears HGH caused in me (and maybe causes in everyone) pseudogynecomastia — enlargement of breasts causes by fat deposits/adipose tissue, NOT necessarily enlargement of the breast gland as people put out as conventional wisdom. I also noticed from myself and others known to have HGH breast enlargement (Alex Rodriguez e.g.) that HGH causes it to enlarge all around the breast not just at the site of the nipple which is where the gland is located, and there appears to be some assymetry as well.
I was considering getting gyno surgery which would have consisted of liposuction and breast tissue excision. Now it appears I won’t need the excision. There are non-surgical methods to treat excess fat deposits all around the body including pseudogynecomastia. CoolSculpting works by freezing fat cells to death and newer Trusculpt works by burning them. I’m considering lipo surgery or the non surgical methods and can update you how this goes for anyone interested.
I am making this post for two reasons, to share my experience which may debunk a lot of the broscientific nonsense surrounding gyno in general and HGH gyno in particular.
I also want to know if anyone else has dealt with gyno (or pseudogyno to be precise) potentially from HGH use and what did and did not work. I have done some research over the last few years and so I can engage with you if you have any ideas.
Let me know!
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basskiller89I've been using peptides for igf, I held a lot of water at first but never had any pain or gyno, I'ma also on an AI for estrogen
What type of gh were you using?
This is all you need to know about it - https://www.ncbi.nlm.nih.gov/books/NBK279105/
Excellent info, thanks for sharing that.
This was a good read, thanks for sharing. It seems to focus on gynecomastia (ie breast tissue) and not man boobs/pseudogyno caused by some other growth (presumably fat tissue). My mammogram showed no breast tissue, so I assume my problem is due to fat as those are the only two types of man boobs I’m aware of.
The question remains how did HGH give me man boobs with no evidence of breast tissue? One section in the publication that addresses adipose (fat) tissue may speak to the mechanism:
“Moreover, not only does total body fat increase with age, but there may be an increase in aromatase activity in the adipose tissue already present, increasing circulating estrogens even further. SHBG increases with age in men. Since SHBG binds estrogen with less affinity than testosterone, the bioavailable estradiol to bioavailable testosterone ratio may increase in the obese older male.”
I know HGH lowers SHBG but maybe it increased aromatase activity in the fat tissue already present in my chest. This is ironic because HGH generally decreases adipose tissue in the body. Any thoughts?
Raloxifene is know to work excellent for gland (https://www.ncbi.nlm.nih.gov/m/pubmed/15238910/) but I haven’t heard of it curing anyone of HGH Gyno, especially HGH Gyno like mine that doesn’t owe to gland enlargement.
No sorry I don’t other than GH raises IGF-1 and perhaps you had an abundance of IGF-1 receptors in the fatty tissue you already had - you never said what BF you had when you ran the GH? I’m not sure if you were also on any AAS but if you were then the combination of raised IGF-1 and the aas binding to the IGF-1 and androgen receptors in your fatty breast tissue as well as raised estrodial from the GH (and aas if you were taking any?) given estrodial is anabolic - especially in fatty tissue - and I believe you create a perfect environment for this tissue to grow. Even if you were not on any aas and depending on your natty testosterone and estrodial levels simply raising IGF-1 could easily have the same result. And yes I know GH is known for reducing adipose tissue but that only happens if you’re in a decent deficit and especially doing fasted cardio just after administering GH. And even then the body fights for homeostasis and BG starts to rise over time leading to increases insulin resistance which promotes fat storage of not in a deficit.
The answers are likely somewhere above and you just need to apply them to your specific situation. Hope this has helped.
I was not on an AAS. Didn’t think I needed one for Hgh. Currently that’s the most plausible explanation—the gh/igf1 combined with some other value (prolactin/progesterone/estrogen) caused the adipose tissue to enlarge.
Most important thing is what to do next. I won’t need breast tissue excision. I’m going to try a DIY coolsculpting belt in the chest area. They charge like $1,000 per session at plastic surgery clinics but the basic science of cold application burning localized fat is called cryolipolysis and based on Amazon reviews many have gotten decent results in places like the abdomen using DIY applicators.
https://m.youtube.com/watch?v=cSLaF7XgMZs
What’s your Body Fat %?
About 16% based on measurements I just did at the house. I am in decent shape. Never had problem with moobs before HGH cycle.
HGH can exacerbate existing gyno but stimulating IGF-1 receptors on the cells causing proliferation of the breast tissue. This is further amplified with high estrogen.
HGH made my existing gyno worse, the lump got a bit bigger. Didnt go away after discontinuing because it already became fibrotic and is independent of the e2 pathway
Sorry I posted my reply above to the OP here by mistake.
based on your experience HGH can cause existing breast tissue to grow and based on mine it can cause presumably the fat in the breast area to expand. I read somewhere that females have very high gh levels which could be why too much HGH in males tends to have this effect.
HGH never gave me issues and I have rarely heard anyone complain about it. You must be sensitive to the stuff in that way. I wish I had good advice for but I simply don't.
My t-levels were probably very low as I had chronic pain and wasn’t active hence why my case may have been so severe. People in good mental and physical health are less prone to complications.