Champion Of The Mind's picture
Champion Of The Mind
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+ 1 Isotretinoin

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Lately I've been reading more and more about Accutane. At first it scared the hell out of me, because I read it could make your acne worst, however I failed to read the quotations about how it only last for 3 months, if that did happen. Reading more and more; I've come to find out that this medication was developed for my in particular acne, cystic acne. I've read that dosages are dependent on weight and the severity of the condition. I wanted someone with positive experience to help shine some light on what dosage I should try and for how long; I read it's a six month "cycle"....... here is word for word what I have found to be a medium between all articles in relativity to the medication....

Dosage

10 mg capsule
The dose of isotretinoin patients receive is dependent on their weight and the severity of the condition. High-dose treatments are administered between 0.5 mg/kg/day to 2 mg/kg/day (usually at 0.5 to 1 mg/kg/day,[17] given as a single dose with food). Usually a course will last 8–10 months. A second course may be required. Efficacy appears to be related to the cumulative dose of isotretinoin taken, with a total cumulative dose over each course of 120–150 mg/kg used as a guideline.[5][6]

Nearly all patients achieve initial clearing of acne during a normal course of isotretinoin therapy. 90% of patients achieve excellent clearance of their acne after a cumulative dose of 150 mg/kg.

Lower-dosage treatments, such as 10–20 mg/day (approximately half the high dosage treatments above), can also be effective, with greatly diminished side effects.[18][19][20][21][22][23][24] However, such lower dosage courses may be associated with higher relapse rates, requiring additional courses, especially if not taken for sufficient time.[25][26][27][28][29]

Usually, a starting dose of 20 mg is taken with the largest meal of the day. After a few months, the dose is increased, e.g. to 40 mg/d. If side-effects permit, a higher dose such as 60 mg/d can be prescribed although daily dose rarely exceeds 60 mg. If 20 mg capsules are supplied, patients may take (for example) 20 mg one day, then 40 mg the next to provide an average daily dose of 30 mg/d. In most cases, isotretinoin achieves a complete clearing of acne during a standard-dose 12–16 week course. Some patients' acne will respond to a course before recurring, necessitating multiple courses of treatment.[30]

Thanks you for your help, I've come to the point where I'm ready to step up and take the risk, damn it bro I want some clear skin.. NPC's and BB's coming up....

johnmarshall12's picture

Accutane is very effective for most users. However, as you know it comes loaded with see effects. So, it's always a personal decision that you have to make. I'm sure you'll make the right call!

Immortaltech's picture

im on accutane right now, started last friday, 20mg a day only, no side effects so far, next week will bump it to 40 mg/day and a week further will see if my liver enzymes increased

Champion Of The Mind's picture

Thank you for the enlightenment bros, everyday I get more and more stoked about it, but I know how dangerous it is; believe me; I will take all the necessary precautions.

GrowMore's picture

If you do decide to go with it regular blood tests are a MUST. Also I wouldn't take any oral steroids while using Accutane (3 months before and 3 months after also).

It's no joke, it's the hardest drug I've ever used in my years.

Immortaltech's picture

bumping this old helpful thread, is taking accutane with provi will worsen the side effects? or provi is g2g

Makwa's picture

The thing with accutane is it can be real harsh on the liver, so don't want to be stressing the liver anymore by taking any methylated orals. Provi is not methylated so it should be ok in that respect but there could be other implications that I am not aware of if taking any orals with accutane.

Immortaltech's picture

Im not a big fan of orals, or any toxic steroids which effect liver enzymes, this would be the only oral im taking along with provi, i thought provi would worsen it, but then its fine i guess, will do bloodwork after few weeks to check

GrowMore's picture

Sorry mate I can’t help.

Champion Of The Mind's picture

What was your beginning dose? I'm thinking about 10mg EOD.

GrowMore's picture

I cannot help with dosages I'm afraid pal. I started on 20ED for 2 weeks then went well past that but that was under regular doctor supervision and blood tests.

Champion Of The Mind's picture

okay, I'll keep looking around, the acutal accutane website says 10mg ED to start.. so I'll keep an eye on this thread and if my accutane gets here before I can get some dose help, I'll follow the accutane website dose instructions. Thanks though bro.

sweetgame52's picture

I took Accutane after high school. Was on for roughly 6 months. Within a month I started to clear up, but was still red everywhere. I suffered from cystic acne also, they take a while to completely heal. The only issues I had was extremely chapped lips and a very dry nose causing nose bleeds. I do not remember my dosage from my first experience. My second experience was this past october through February and 10 years later. Once I started juicing my acne came back worse than ever. I didn't know where to get the isoterinion. I suffered for almost 2 years with it. If youve had horrible acne you know there is nothing worse. I've never had any issues other than the chapped lips and dry bloody noses. I started dosong at 20mg and worked up to 50 for around a month. Then tapered down to around 10mg a day for the last month. I just sorta stopped once I felt it was completely gone. Been on juice since without any flare ups at all. Personally, I love the stuff. Idk where I'd be without something that actually cleared me up. I really feel like it gets negative publicity for reasons that aren't actually there.