i20bpm's picture
i20bpm
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+ 7 Glucophage/metformin? Everything & Anything

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Glucophage/metformin
Metformin is a widespread type II diabetes drug used by those who have diabetes or are at risk of suffering from this condition, such as obese patients. In addition, it helps reduce low density lipoprotein (LDL) cholesterol and suppresses glucose production in the liver. Currently, it is listed in the World Health Organization's (WHO) list of essential medicines.

It belongs to a group of drugs called biguanides, a group of antihyperglycemic drugs. It increases the transport of blood sugar across the cell membranes into muscle cells. The action works by positively effecting cellular insulin sensitivity.

Bc of this it's had a place in bodybuilding for sometime now. But new claims suggests it has a life expanding effect as well. The link is below. http://www.medicalnewstoday.com/articles/280725.php

Now let's get to the nitty gritty. I'd like to hear from other members who have ran this with success. Is it safe, worth it? Dosages etc. I'd like to hear it all, perspectives and everything.
I've seen some old posts on this but nothing too recent so it seems like it is fine to talk about this drug in forums.

MedDx's picture

Here's some drug interactions I found in a book...Chlorthalidone, corticosteroids, diazoxide, epinephrine, ethacrynic acid, furosemide, phenytoin, thiazides and Thyroid hormones can all antagonize the hypoglycemic effects of antidiabetic agents. ETOH, anabolic steroids, guanethidine, MAO inhibitors, propanolol and the salicylate can all increase antidiabetic agents hypoglycemic agents.

i20bpm's picture

Ohh damn good find I'll have to look into the corticosteroids interaction in particular

MedDx's picture

I know Taurine is not contraindicated while using met...so incorporating it as an adjunct Rx could be beneficial...something tells me that hydration is gonna be key to making this drug work, especially with any AAS on board...