DocMcGains's picture
DocMcGains
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+ 1 Low Dose Tren Duration

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I’m presently cutting on 300 test, 240 primo, and 70 tren ace (ED injections). I’m down to 198 average from 214, feeling tighter and stronger. I started the tren (the new compound in this cycle for me) at 6mg ED, and titrated up to 10mg ED. So far, so good: no sleep disturbances, no night sweats, BP stayed the same. I plan to run bloods in a month, after about 6 weeks on this cycle to see where things stand. I was originally planning to run the tren for 8 weeks and then drop as a jumpstart to the cut, and if bloodwork comes back questionable I will drop it right away. But assuming bloodwork comes back clean, how long have folks run low to moderate dose tren before seeing their markers go sideways?

It is a classic case of “I feel great! Can’t I just stay like this??” I think the longest I would extend would be to 12 weeks rather than my initially planned 8. What do the wise minds arrayed here suggest? What have you seen or experienced in your own experiments with this compound? Thanks in advance.

DocMcGains's picture

I appreciate that- I am definitely in what was described below as the “superhero” tren honeymoon. Consensus seems to be to pull the plug at 8 weeks, regardless of bloodwork. That is likely what I’ll do, even if it means cutting the honeymoon short.

DocMcGains's picture

Get off my post, bot.

Novalentinehere's picture

If you’re not a bot you’re a douchebag for posting your introduction on this man’s thread.

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-Infidel-'s picture

bot!!! This is like the 3rd thread you posted this.... what are you trying to sell us?

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3wt's picture

You might not see your bloods ever get too concerning on that dose, but bloods don’t show the full picture. Neurotoxicity will still be rampant in the background, so will cardiac remodeling, as well as organ growth. I wouldn’t run any dose of tren for over 12-16 weeks as it’s just not worth it in the long run.

Teeeethreee's picture

If you keep on using it eventually won’t have the super duper pop you like. Save it for when you’re competing as a treat and big gun you can deploy when strength and energy is low and you wanna die lol

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DocMcGains's picture

Good to know. I'm 41 this fall, and have a loose plan to do at least one show before my 45th birthday. Until that first and last real prep, I probably ought to keep it to a minimum.

BigCoachKen's picture

At low dose, brain health would be my main concern. Ive been tempted to run the 10mg/day experiment, but ive already got blast injuries. I already "cant find" words sometimes, I dont want to be a jacked veggie

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Jockstrap's picture

If its 10mg a day you're wasting time. 75 every day you might get 6 weeks. Blood will be altered.

I've never seen good bloods on tren ran properly

Storm Ayden's picture

I personally wouldn't go offer 12 weeks. I treat tren like an oral. No more than 12 weeks. Even if bloods come back clean I just assume I got lucky.
Why ? It's probably the most neurotoxic and cardiotoxic steroids.
You may have good bloods but we cannot verify your BDNF. We have no way of testing how the tren is changing your brain chemistry.
Plus the dopamine downregulation will feel horrible once you go off the tren.

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msten_ranger's picture

100% this I tried to warn my friend recently about the post tren crash. He ignored me, ran it for 16 weeks and is struggling to get in the gym now. Tren paranoia slammed him too towards the end too.

-Infidel-'s picture

"Plus the dopamine downregulation will feel horrible once you go off the tren."

That's what i would be worried about. The dose is too low to really worry about prolactin, or serious organ problems, the problems will arise from things that cannot be measured by lab work ie) cognitive function and dopamine regulation... 20 weeks can* leave one depressed with brain fog

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DocMcGains's picture

That’s good advice and sound reasoning. The dopaminergic compounds can do weird stuff, especially coupled with the drop in positive psychological feedback from great gym performance. Those two things together drive a lot of the post-cycle slump.

-Infidel-'s picture

and you will sound like a retard trying to come up with full sentences at work, or giving presentations, or anything else that requires a little bit of critical thinking

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Petecastiglione's picture

Idk i feel way better mentally when i get off tren i never heard anyone feeling worse coming off but everyone’s different i guess

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-Infidel-'s picture

I wasn’t saying those symptoms happen coming off, I’m saying the symptoms start some time during the cycle then get progressively worse as the cycle continues.
The longer the cycle the shittier the “brain fog”.

Coming off makes me feel a lot better myself, and those symptoms slowly go away.

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Petecastiglione's picture

Ohhh okay yes that is accurate for me too. I was gonna say once I’m off ace i feel a lot better in a week or so

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-Infidel-'s picture

For sure… I never ran 20’weeks of tren, 12 was the longest and by week 11 I couldn’t wait for it to end. I pushed it just to say I could. My last tren cycle I quit at week 6 hahahah but that was due to insomnia

I was speculating that if one is having cognitive function problems in week 10 of 20, then by week 20 the users brain would probably be mush.

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Pandateston's picture

Exactly, Pete.

Most people I know actually feel relieved when they come off. The CNS stress, sleep issues, and dopaminergic adaptations that build up week after week start fading away.

What some guys miss isn’t feeling good on Tren … it’s the physique, gym performance, aggression in training, confidence, and that “superhero” phase from the beginning.

Two very different things, in my opinion

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press1's picture

I've always felt great when coming off it, felt human again and happy - the only thing that negged me out was seeing my lifts go down after a week.

Pandateston's picture

Same here, bro !

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Petecastiglione's picture

Have you ever heard of this? @Pandateston

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Pandateston's picture

@Petecastiglione … Pete, no. To be honest, never.

It’s the opposite

What I’ve seen with Tren is that it’s highly stimulating in the beginning. During those first couple of weeks, especially with acetate, a lot of guys feel like superheroes … confidence, drive, focus, libido, gym performance… everything seems elevated.

The honeymoon phase usually doesn’t last forever though. Chronic overstimulation of the dopaminergic system can lead to adaptations in the brain, including reduced receptor sensitivity and neurotransmitter signaling. Whether that’s true receptor downregulation or other CNS adaptations, the end result for many guys is the same: less reward, more irritability, less patience, more stress, worse sleep, and sometimes even a bit of anhedonia. (I personally don’t get the irritability. What hits me is the anhedonia. It can get pretty severe, especially with acetate.)

The severity varies a lot from person to person, but that’s why you’ll hear so many guys say they actually feel relieved when they come off Tren. The gains are great, but the CNS burden can be very real.

That’s been my experience, and it’s pretty consistent with what I’ve heard from a lot of long-term users as well.

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press1's picture

You have to remember a lot of these guys saying these weird things about Tren nowadays aren't actually running it at what everyone use to run being 350mg Plus per week.

Pandateston's picture

Good point, Big Press !

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-Infidel-'s picture

Ok… no one is saying that people feel worse coming off of tren. It was a miscommunication.

If coming off made people feel worse, no one would ever quit. There would just be dudes using tren like TRT.

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press1's picture

My comment wasn't aimed at you bud - more so at the guys who run 10 to 20mg per day then brag in the forums that they never get any tren sides.

-Infidel-'s picture

Yes, I’ve been over thinking shit the last couple of days. I need to get labs done and find out wtf is going on.. might be just readjusting back to schedule

Plus the gf is out of town and havnt gotten laid in like 3 weeks… im sure that has something to do woth my overthinking and analyzing everything… its getting annoying

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press1's picture

Its probably because you have been on holiday and not been in the thick of training - training keeps me feeling numb and chilled which is how I like to feel. Which is basically the opposite of how I've been the last 8 weeks since anything I can lift right now is too light to numb my CNS lol It was the HOTTEST day on record yesterday in the UK for June!! Another 3 days of it yet too and its doing my head in Lol

-Infidel-'s picture

Yea man, plus if you are not drinking enough water and staying hydrated and cool then you are fucked. Especially if the heat is fucking with sleep

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press1's picture

Ain't got much muscle on me currently bud so nothing really to hydrate LOL Seriously, its amazing how much less water intake you need when you are no longer swole LMAO

DocMcGains's picture

Helpful info. Thank you.

Storm Ayden's picture

Yeah you'll feel super empty and down. I usually use some or semax, adamax or selank to give myself a boost. However I will not be touching SSRIS forget it.

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DocMcGains's picture

TRT got me off Wellbutrin. Not an SSRI (rather an NDRI - another dopaminergic compound). Test was far more effective for a wider range of my depression symptoms, and didn’t elevate my BP.

Wildling's picture

I’m on Wellbutrin for anxiety. My brain runs like it’s turbocharged 24/7 lol.

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Storm Ayden's picture

I've never heard of NDRI, I've got some reading to do ! Test is usually more effective cause it treats more broader mental health issues.
Glad to hear you got symptom relief from test. Test is best !

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DocMcGains's picture

Yeah, it really worked wonders. Bioidenticals for the win! Credit to the one PCP I saw way back in the pre-pandemic times who was keeping up on the literature around declining testosterone and when I described symptoms (anhedonia, sexual dysfunction and general lack of desire, no drive etc.) recommended a blood test. It took six years, but he was proven right.

SSRIs were NOT for me. I had a terrible response, but Wellbutrin worked well for me for some time. But then, it did not treat the full range of symptoms. Test did. I'm now the evangelist for HRT in my peer group.

wanted's picture

10 mg aday This is new to me. Cant wait to hear your results

DocMcGains's picture

I have yet to see the improved nutrient partitioning, but the CNS stimulation is definitely there at that dose. Gym drive is excellent and strength is up. Pumps are insane. I will share pics in the full cycle write up.

-Infidel-'s picture

Do you think the improved nutrient partitioning is bs? That would be one of the main reasons why i would use low doses

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SeeOhShow's picture

Negative tren has been found to actively inhibit the de novo lipogenesis metabolic process which is what turns excess carbs/glucose floating around in your bloodstream into triglycerides.

-Infidel-'s picture

even at low doses? ie) 90-120 mg a week

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SeeOhShow's picture

From what I’ve read yes. It’s obviously dose dependent, but it’s not an on/off switch. It’ll be a sigmoid curve

-Infidel-'s picture

That makes sense

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DocMcGains's picture

This was anecdotally confirmed by Dr Dean and Vigorous Steve - they were basically the inspiration for the experiment. The claim is that improved nutrient partitioning and CNS stimulation are the two main positive effects of low dose tren. Less of the strength and crazy anabolism for which the compound is best known.

My diet right now is dialed at 250g protein, 250-300g carbs, >50g fats. It is pretty hard, though, to assess nutrient partitioning...

SeeOhShow's picture

I haven’t seen that video yet. I did watch the chase irons one where chase talked about pinning 200mg tren a day and constantly going hypo all day regardless how many carbs he ate lol. I think it was ace?

Storm Ayden's picture

200 mg of tren per day ? I would die wtf

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SeeOhShow's picture

He claims that was ran solo. Back in the day the forums were full of the dumbest advice for cycles. So that was 200mg tren a day with no test base or nothing. Actually it might have been 300 a day because at one point he said 2g a week