Revised cycle plan for April – bloods included, feedback welcome
Got pretty heavily criticized in my last thread (fair enough), so I took the feedback on board, reassessed, and put together the following.
I finished PCT late December and I’m planning to start this run in April, so there’s a solid gap off. I’m mainly posting to sanity-check where my health markers are at going in.
Recent bloodwork (this week):
Serum Androgens
Total Testosterone (Siemens): 22.9 nmol/L (8.3–29)
SHBG: 38 nmol/L (11–71)
Calculated Free Testosterone: 441.4 pmol/L (255–725)
Albumin: 47 g/L (38–50)
From my perspective these look reasonably well recovered post-PCT, but I’m open to other interpretations. I still plan to run additional labs (lipids, hematology, CMP) closer to the start date.
For context, I ran something very similar last year, and training outcomes over the cycle were:
Chest: +21 kg (+36.8%)
Shoulders: +23 kg (+44.2%)
Triceps: +12 kg (+19.7%)
Back: +14 kg (+23.7%)
Glutes: +34 kg (+56.7%)
Hamstrings: +26 kg (+43.3%)
Quads: +22 kg (+36.7%)
I’ve attached the planned cycle layout for reference. Not claiming it’s perfect — just aiming to be more conservative and structured than last time.
Constructive feedback is welcome. I’m especially interested in whether anything here looks off from a health or recovery standpoint, not hype.
| Weeks 1-16 (presc.) | Tirzepatide | 5mg weekly | ||
|---|---|---|---|---|
| Weeks 1-16 | HGH | 3.3 IU daily | ||
| Weeks 1-16 | Test E | 300mg | Pin half Mon/ half Thurs | All oils in 1 jab |
| Weeks 1-16 | Primobolan Depot | 600mg | Pin half Mon/ half Thurs | All oils in 1 jab |
| Weeks 1-16 | Masteron | 400mg | Pin half Mon/ half Thurs | All oils in 1 jab |
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Smells like a troll. Lol
Def's not a troll just trying to get solid advice. Appleguy has been incredibly helpful.
Your Estrogen is going to be Crashed and you are going to feel like shit with Primo and Mast
Was just gonna say at 300mg of test is this the “I’m dying to crash my estro stack”?
2 to 1 test to eq, mas, or eq. That cycle you posted is gonna have your e2 at 0. Im at 500 test e 250 eq and run really low e2. I run hcg and dbol to balance my e2 out. Run a 2 to 1. Then get bloods after 6 weeks is how l run.
Have you ever taken primo and do you know how it affects your e2?
This is recipe for disaster if you do not know how primo affects your e2. You should be running your test higher than the primo and figure out how much of an AI primo is to your body with bloods 4-5 weeks in. Most start with running test to primo at 1.5:1 or 2:1. The mast won’t effect your e2 so run that however you want.
It’s my understanding that primo doesn’t aromatize and isn’t a true AI — at most it may have a mild anti-estrogenic effect depending on the individual. Because of that, I’m not planning to “chase a ratio” by automatically pushing test higher than primo.
From what I’ve read and seen in bloodwork discussions, E2 levels are more about total aromatizable substrate (test dose), body comp, and individual response rather than sticking to a fixed 1.5:1 or 2:1 rule.
My plan is to start at a moderate test dose and check bloods around week 5–6 to see how E2 is actually responding before making any adjustments. Not looking to bump test just to satisfy a ratio if levels are already in range.
Open to data-based adjustments, just trying to approach it conservatively.
Let me educate you some. Primo is not an Ai and does not directly lower estrogen in such a way. What it does do is it binds to a androgen receptor displacing Testosterone from binding and turning into Estrogen. Primo does not turn to estrogen but blocks testosterone from binding and aromatizing to estrogen so over time your E2 lowers.
Primo is also antigonadotropic, your body reduces or stops its natural testosterone production and guess what? Less Test less Estrogen. There is a reason why Test should be higher than Primo.
Then on top of this you are adding in Mast so you're test is 300mg and then the other two compounds that affect estrogen are 1000mg or 1 GRAM! Disaster waiting!!!
Go ahead and run your cycle but don't come and complain that you feel like shit and your E2 is crashed.
Cheers for this - As mentioned have done something similar and felt okay - Seeing as you seem to know what you are talking about I am generally interested in what you would tweak this to look like? Would greatly appreciate the feedback!
Test 600mg, Primo 400mg, Mast 200mg, HGH 3 to 5 iu a day depending on how your body does with it.
Blood work is key, try it and test it. I do not not know exactly what all you are trying to achieve but if it was me, I would cut the mast out all together. You have Primo and HGH to build muscle.
Mast acts more like a Serm for the estrogen affect, so it basically only affects the E2 in certain tissues such as breast tissue by binding to a receptor.
If you were to do Mast would you go concurrent or towards end of cycle?
I would go concurrent and run for at least 10 weeks if I were doing mast. It's a good compound its just not very wise to have it in this cycle with Primo anyways not at those dosages. If you cut Mast you could even up the Primo a little more.
Sweet thanks much. I more or less landed on this last night after some more research. I reckon I will drop the Mast.
There is nothing conservative about doubling your dose of primo to test without knowing how the primo will affect your e2.
I will look forward to the thread in 4 weeks about why do I feel like shit. Help me.
I respect not wanting to chase ratios, that being said I do think this is risky.
Both primo and mast can have some AI effect (with variance per person)
I would have some fast aromatizing compounds on hand just in case (TNE or dbol)
Ranger3252It’s not an AI, it’s an AAS. Certain compounds will crash E period. Just as certain compounds will raise your E such as dbol etc… stop using AI (artificial intelligence) to rely upon. Use science and research such as this to understand what you’re doing. Primo will crash your estrogen as fast as EQ. You need to reevaluate your next cycle, right now it’s set up for a disaster scenario.
I swear this is that retard from the other day just with another account.
Ranger3252I think you’re absolutely correct
I'm probably the same retard - I posted and then tried to tidy things up again. Am asking for advice/help - Heaps of people telling me it's a shit cycle but not really chipping in with much in the way of help. Billybear and Appleguy (you too) have said some useful things to consider.
Isn't a gram of Primo/Mast going to nuke the fuck out of your E2 with that little test?
Ranger3252Yes
Cheers will look into it.
Responsed above
Will you be able to eat enough to gain muscle whilst running 5mg tirz per week?
Yeah dude, I go pretty light during the day (usu. protein shakes or the odd tins of tuna etc.) but my appetite peaks at night and I just go fucking hard on meat and veg!
I prefer just meat nightly. Secretly….
Picturing a man eating cold cuts in the dark lol
That's not the picture he painted for me.
By the end of it there is a picture painted.
Wish I could help. I don’t know much about primo or masteron
They were kind to me last time. I tend to avoid anything that can fuck my liver too hard. I'm trying to give up the booze for good this year though. This will probs be one my last cycles anyhow.