posted Wed, 10/04/2023 - 04:41
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+ 2 Carrier Oil
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Is there any truth to the type of carrier oil changing the half life of the product?
I see many people love MCT vs. Other Oils but is there any truth to the type of carrier oil changing the half life of the product? Ofcourse the viscosity is different but what about half life? I have seen a few people mention it but nothing substantial or any real sustantial tests done to say yea! or ney!
Example:
Test C in Castor Oil
vs.
Test C in MCT Oil
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My advice is don’t lose sleep over the small stuff. Use a carrier that agees with you and time your shots based on ester irregardless of carrier.
A million times agreed!!! We’re talking about a matter of hrs or even 1/2hrs with the carriers.
Do what works best for you and your body.
The thing is Serra's bloods show a 200ng/dL difference. He even mentioned injecting two days earlier with the test U in mct as opposed to pharma Test U in castor oil. Not even mentioning that study. So there may be something to all of this. But yea no biggie, just preference.
And half-life, what was in him already? injection site? body temp? activity level? metabolism? hydration? amount of sleep? BP? Time of day for testing? hours after last injection? etc., etc.
Those are valid questions that hopefully can be answered by him @Serrajitsu0876
Everything was the same no need to change a variable. VG shots, both 6am fasted on 8 hours of sleep etc. I even sent a sample to Jano to get it tested to get the dosage down. I’m shocked there’s still guys arguing against science. You can lead a horse to water…
The castor oil preparation had a longer half-life than TU in tea seed oil.
That’s a line from the study. You guys can continue to bicker about it but I’ll choose science over a “steroid expert or pro”.
Not buying it. Let's say the castor oil acted as a buffer (trapping the active ingredient in a "bubble"), not allowing the ester to decarbonize until a day later. What does that translate to? A virtual delay in your pin day. Meaning you're not getting what you want up front when you pinned and more on the backend. Giving the illusion of "longer half life".
In your example as a stand alone drug it wouldn't matter. When you start stacking trying to time release I can see it being a bigger issue.
Just trying to be fair that's all. I think your point is proven though. Thanks
I'm convinced but thanks man. Much appreciated. Would give you some likes but it won't let me.
Good advice but Nah lol hopefully no one is losing sleep over this because it isn't that crucial. At the end of the day mct oil does the job just as well. Just comes down to preference that's all.
I've lost a lot of sleep. Ended my cycle for now.. I just know what I like and rather not put something in my body unless I know it's what I want.
Loosing sleep? Remember Big pharma is using the same carriers. I believe you have something else going on beside carriers?
Damn what happened?
There's just certain items I don't run unless its in the formula I want or if it's from a brand that's no longer around. I guess I'm going somewhat natty and I'm ok that.
What's funny is I just ran out from this old brand I'm talking about with the goop. So I was able to A/B it against these newer labs with MCT and there's a obvious difference over and over. So if I can't find what I use to have I'm not spending money.
Brewing, and quality that’s the difference.
Good point. Not to bash UGL but lets talk straight, alot of synthesized materials are often low in purity. Could be contaminated with other chemicals, industrial solvents, heavy metals etc. Some underground laboratories do not have access to the same highly pure USP grade pharmaceutical ingredients used by Pharmaceutical companies. Now that's not to generalize all UGL's. Noticed I said some UGLs.
I think that's it. I am trying to think of individual factors to search for, hoping I find what I used to have. But the scary thing is, I haven't found the quality I was getting. Seems like everything is different now. I just ran out of that last vial of goop a few months ago so I was able to put it against this new stuff... I guess I'm not spending money on this anymore.
You sound even more stubborn than me! I think @FlemDaddyKush has some info for you. Look into it.
But yeah folks may say nonsense but I can tell a difference. Been doing this long enough
I'm gettin old and stubborn. Cholesterol rising just cuz.
And you or anyone that think that is absolutely right. We can sit up here and assume all day but lab work doesn't lie. I'd like to see labs myself. A pharmacokinetics lab study of both would be the answer.
Is BroScience and Bidenomics sort of the same thing? Lol
I thought bro science was one step above bidenomics
Kind of along the lines of "Scott Steiner math" for wrestling fans.
Haha, true.
Lol. I think so. That guy is done. Stick a fork in him. I told ya that you got my vote!
We need a man of the people
America would never allow a Black Conservative lol. I defy all odds. Remember when Biden said on the Charlamagne tha God show that "if you vote for Trump, you arent Black". So i dont know what i am. Im not Republican or Democrat just a God Fearing Conservative..
Fwiw. We really were routing for Ben Carson. He's a good man..
Yea I do remember when Biden said that.
We both use common sense in politics. I think that's what we have in common.
I keep a stock of filtered grapeseed oil, couple 20ml bottles for them 400s or 375s that bite. But to answer your question dont believe Tiktok
Not sure where you heard that except perhaps in your own thoughts.
Ester is your half life. Oil is just the carrier. Pinning properly keeps your blood levels stable.
Thanks. Its one of those where I wondered if I should be splitting my dose up of Test C more often if it is in MCT vs. Castor.
Trial and error I guess.
Pinning frequency is based on the ester not the carrier oil
Not sure on that but I do know I prefer gso, which I'm not seeing all too often these days. Primarily for the healthy skin benefits
Anything that you will likely notice......no. Once again what it says on paper doesn't have a big influence in real life. What you may notice is that caster may leave you with less pip depending on the situation. Comparing with MCT, which is assimilated very quickly and can leave just the hormone behind which may then cause some pip after a few days. That bolus of castor seems to sit there for while kind of acting as buffer, for lack of a better term, for the actual parent hormone. Ironically though, I don't like castor. Way to viscous and with all the pressure needed to get it out of the needle I end up with pip regardless because the needle ends up moving around to much. Use a larger gauge needle you say, well that causes more trauma sticking a harpoon in me too, hence pip. The Cadillac of carriers is MCT/miglyol and that is why you see a big share of the UGL and big name brands switching over to it.
Its hard to say exactly because it's controversial subject. Because a lot of people say that the ester is what controls half life and such. The difference is that mct is absorbed in hours vs castor can take days to fully absorb. So test u you would want to have in castor oil because it will extend the half life, you would not want to make test prop in castor oil cuz that kind of screws the whole fast absorbtion and faster hitting effect of the compound. Pharma uses castor and cottonseed oil because it's the most studied and cheapest oils. They don't use them because they are better. For short esters you want it to be absorbed fast so castor isn't good for that. Longer esters like test cyp and E can have a longer half life if brewed in castor oil but most places don't use.castor. the most popular oils are mct and gso.
If I could give you +3 I would. I think we are talking more of a supporting role by oils.
That test prop comment would be a good example. I'm willing to bet test prop in castor oil won't hit as fast as test prop in mct oil. If I'm wrong I'm wrong.
Like you said this is debatable in my opinion but you'd think it wouldn't be...or at least shouldn't be. I notice test undecanoate in mct oil. Now technically if it's undecanoate ester then it will have stated half life of x amount of days, that's a given. Now the question is was there a reason why pharma used castor oil instead of say, cotton seed or sesame seed oil? In my opinion castor oil was chosen for a reason. Also the release time of a steroid is based on a few factors, location of pin, type of ester and in my opinion, the viscosity of an oil which some disagree with. I just know I feel a slight difference with GSO or cottonseed oil. Been saying that for years.
Yes like you said I think they used castor for a reason on test u, the oil is.not gonna change the half life of the ester but rather it delays the onset of the ester starting to absorb, where as test u in mct will be starting to absorb in hours vs test u in castor will take days for it to be absorbed. And yeah the test prop was a good example, but a even better example is say test no ester in mct vs test no ester in castor oil. I don't think TNE in castor oil would make people feel much of anything.
I think both examples would be good. TNE and Test Prop in mct vs in castor oil. I knew some would disagree but it's worth discussing. I would like to know why did Pharma decide on castor oil as the oil for test undecanoate. Is it because it had better solvent properties or what? In my opinion it supports the ester. I remember @Ghost and myself were discussing this.
Well, you tossed my above post out the window. Oil has nothing to do with half-life as Makwa basically described. The oil carries the crystalline ester into the muscle, it's viscosity may affect how concentrated or dispersed it is in the muscle. The oil will be dispersed within hours or days, the ester can take much longer. Take a piece of hard candy and put it in the center of some soft milk chocolate. Pop it in your mouth. In a short while the chocolate has dissolved away, in a long while so has the candy. How long the candy lasts depends on how hard it is. (like an ester)
There’s actual pubmed studies showing carrier oils affect absorption rates.
Absorption kinetics are affected by the viscosity of the oily vehicle, concentration of the ester (the higher the concentration in the depot, the higher the driving diffusion force for release), the volume of the product, and the site of the injection.
Source: PMCID: PMC9006970
Can you please post this on top of first page. I figured oil viscosity was a factor. Thanks
http://cbpmedia.cbp.pitt.edu/faculty/schlatt_lab/PDF/2005J%20Med%20Prima...
Albeit this is a study on castrated monkeys, it still shows the same. Check out the chart on page 4.
This must've been a joke.... please tell me this was a joke. So all this arguing over a study on monkeys?
You got a pro bodybuilder saying it doesn't matter and use your energy elsewhere. Lol.
Idgaf.. what some study says by some schmucks in lab coats. I'm listening to the guy i wanna look like, who's where I'm trying to get PERIOD!!!!
Nah what joke you talking about? Dude is a credible member point plank. He's sent a lot of Jano tests and has done plenty of bloods. So yea what he said is solid. Oil type did indeed affect he test levels while on test U according to his bloods. I miss the dude. Solid guy