bmurphr1's picture
bmurphr1
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Why the F is cabergoline so expensive!?

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After being on Test now for several months (around 125mg weekly of cypionate), 0.25mg of anastrozole E3D, and 250 IUs of HCG EOD I've received my last lab testing results and found out that my prolactin levels have been elevated. To be completely honest, as much as I know about gear now I'm not all that surprised that I've jacked my levels up over LabCorp's threshold (it's just shy of twice the max value of prolactin in males according to their cutoff ranges). Anyways, my endo obviously wants to add cabergoline to my stack as well but looking at all of the normal pharmacies in the US as well as abroad it seems that cabergoline (as well as Casaber and all of the international versions of cabergoline) are just freaking expensive compared to other AIs and ancillary-type drugs. I'm not asking for a source for the cheapest version, because I'll be able to find that source myself, but my question is why in the hell is cabergoline so expensive? It's been out for at least 25 years now, and generics have been out for ages - not to mention the OTC price of cabergoline in other countries like India should be practically pennies on the dollar per pill I would have thought.

Personally, I hate that I have to take 3 different medications to combat the side effects of Test but that's the price I have to pay for cruising on Test permanently (I'm a TRT patient so it comes with the territory as well) but the other two ancillary drugs I've found for dirt cheap either through other sources or by getting creative and asking my doctor to write prescriptions for six months of medications all at once...since a single 30-pack of anastrozole was only $6 at a popular unlisted American mail-order pharmacy...mailed in the paper script and in 10 days had the medication in hand when the same amount from my neighborhood pharmacy would have been close to $100 USD. The other drug, bromocriptine, that also helps with prolactin levels is much harder to dial in on the correct dosages and it has a smaller side-effects curve in the sense that too much could cause more of the nasty side effects that I'm trying to avoid by using cabergoline. I'm just curious at this point why cabergoline costs so much money when other ancillaries can be found so cheap. Any insight into this one would be appreciated very much. Cheers.

bmurphr1's picture

I just found out about another drug that I haven't heard of being used for high prolactin levels before...pramipexole. I just checked online to see how much pramipexole is and prami is WAY cheaper than cabergoline. I think I might have just discovered a good alternative to cabergoline that I can actually afford. I need to do a little research into this and see how well prami works in comparison to cabergoline for high prolactin levels.

bmurphr1's picture

My endocrinologist prescribed everything except for the additional testosterone that I'm pinning...the HCG, anastrozole, and cabergoline are all prescribed by the same doctor but he's not the smartest doc in the world. He prescribed me a whopping 2mg of anastrozole per week when the dose should be 0.25-0.5mg max per week so I don't take the full amount. The HCG dosage is the exact dosage that he prescribed, and I take half of the amount of cabergoline that he prescribes. If I took everything that the doctor prescribed at the same dosages I would have absolutely no E2 and wouldn't be able to get a boner if my life depended on it. This is also the only endocrinologist that I can see right now because they are so hard to get an appointment with in my area. Lastly, he only prescribes 100mg of test. cypionate every two weeks...at those dosages it would just shut my HPTA down and keep my testosterone at my pre-TRT level of 185 ng/dl or even less...so while I wait to see another doctor I have to deal with this guy so I have to do the research myself and make sure the dosages he prescribes are right - otherwise I'd end up much worse off than I was before I even saw the doc in the first place.

Makwa's picture

He prescribed me a whopping 2mg of anastrozole per week when the dose should be 0.25-0.5mg max per week so I don't take the full amount.

Is this based off of previous bloodwork?

I take half of the amount of cabergoline that he prescribes

Why? Has bloodwork confirmed you only need half.

he only prescribes 100mg of test. cypionate every two weeks...at those dosages it would just shut my HPTA down and keep my testosterone at my pre-TRT level of 185 ng/dl or even less.

Once again, has this been confirmed through bloodwork?

bmurphr1's picture

It's all based off of previous bloodwork. The endocrinologist that I see does not specialize in TRT at all and only prescribes my testosterone because he's the only endo in my area that accepts my insurance and my primary care doctor refuses to script me any test because of my past history with substance abuse (which I can't really blame him for). I had bloodwork done before I ever started on any testosterone and my prolactin and E2 were in check and when I took 100mg of test biweekly as he prescribed my test went from 180 ng/dl to 185 ng/dl (tested on day 10 of 14) - and then told me "if this dosage of testosterone doesn't help you then we need to try something else" as if 100mg of testosterone cypionate every 14 days is the maximum dosage that can be safely taken. The only reason I was started on anastrozole is because I was starting to show some signs of gyno with the itchy nipples but no real breast development and that was when he presented me with a script for 8 tablets of anastrozole 1mg with the direction to take two whole pills weekly. It was at this point that I knew that he wasn't the smartest tool in the shed when it came to excess estrogen in men on TRT, but there's also a slight language barrier since the doctor is from Syria and he has an accent that I can't understand 100% of the time. If I had taken 2mg of anastrozole weekly as prescribed, you can imagine the ramifications especially when he hadn't even tested the current estrogen levels at that point in time. I'm not saying that I know any more than the endo does, but I do know that 2mg of anastrozole based on the most recent labs drawn at that point in time would have been hell to pay especially considering my primary care doctor about pulled his hair out of his head when I told him what my endo prescribed me. He was even the doctor that encouraged me to stick with 0.5mg weekly, because I was going to take the full dosage until I saw him the next day for my 3-month follow up appointment. When I was prescribed 0.5mg of cabergoline I checked with my PCP to make sure that it was an appropriate amount after discovering that my prolactin levels were elevated and he agreed that it was a proper dosage. When it comes to AIs and everything besides the testosterone, I usually get a second opinion but I do take more testosterone than he prescribes.

Cabergoline is expensive as hell though, even with prescription insurance here in the US...It's surprising that I can pick up 30 tabs of anastrozole for $6 but I pay the same price for a single pill of cabergoline from the pharmacy down the street. I'm in the process of looking for a cheaper alternative to it so I don't have to pay the outrageous American prices of the stuff.

irongame427's picture

Ya its expensive, and bad for ones heart. Thats why i went into my docs office and said i had restless leg syndrome and got prescribed prami. I can walk into cvs and get 30 .5mg pills a month for 5 bucks. Its stronger then caber in terms of lowering prolactin, the acute sides are worse but not harmful ( some nausea if you dont slowly taper up) But if you start low, .125mgs for a few days then go to .25mgs for a few days then up to .5mgs ed you should experience little to no nausea and you take it right before bed. And it has the benefit of stimulating the release of gh at night time.

bmurphr1's picture

RLS is when you are laying down at night and you can't lay perfectly still because you always feel the sensation that you have to move your legs around. Imagine trying to lay perfectly still in your bed falling asleep and you keep being bitten by an ant and your body just instinctively makes your legs move around to relieve the sensation...that's what RLS is. I've experienced RLS way too many nights in my lifetime, but this was when I was withdrawing from painkillers and was sweating and had insomnia from coming off all of the drugs.

PPGfreak's picture

You have a very good point. I can buy a bottle of test for less than four Caber pills lol

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bmurphr1's picture

Yeah...I can see big pharma (i.e. US) wanting to charge an arm and a leg for the stuff, but I'm in the market for some generic Indian cabergoline...I don't necessarily have to have the Casaber brand stuff to be satisfied. At the same time though I know how rampant counterfeiting is over in India and don't want to end up getting stiffed so I really need to do my homework before I decide to order some non-brand name cabergoline from an international source - as always of course.

Nice screen name by the way ;-)

bmurphr1's picture

Done...and thank you very much.