A little caution for the Juicer.
So, the other day I was sitting on the shitter reading the Journal of Biological Chemistry (What now bitch?) and I came across a study in mice that linked the sudden drop in testosterone to Parkinson's disease. I thought this was interesting. Especially because it had something to do with testosterone. I love everything testosterone related.
In this particular study they found that the sudden drop in the levels of testosterone following castration is sufficient to cause persistent Parkinson's like pathology and symptoms in male mice.
Who gives a shit right? Well you should give a shit because when you go off cycle you experience a sudden drop in testosterone similar to that of castration. Right?
This could be setting the stage for Parkinson's disease.
This to me gives cause to reflect a little and think about how careful we need to be with this stuff. Parkinson's is a pretty nasty disease and I have reason to believe that this is something that all need to consider before cycling.
Be safe, be smart, and consider everything before you make the decision to juice.
Anyone have any thoughts on this?
All my love, no homo
Edward
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My ol' man has early onset Parkinson's , neurologist has put him on high dose prami for the dopamine antagonist effect. Is this publication on pubmed, would love to check it out.
As someone noted below, the correlation of dropping test relates to dopamine levels. However, at this point there really is not definite answer to what causes parkinson's, since many people have the onset early on as 20-30 years of age.
While I highly doubt that could be a primary reason, the disease is a nasty bitch. Seen my dad go from the energetic bad ass he was his whole life to 1/4 of it in the past year...one of the reasons I decided to go into medicine in the first place was to do more research on the diseases.
When I read about the dangers of steroids, I gave up reading.
Like I said earlier it is interesting but at the same time if it were true don't you think that it would have been all over the anti-steroid crowds radar? I would bet heavy cocaine use or getting punched in the head a lot will give you a better chance at parkinsons than Test. Richard Pryor, Robin Williams and Muhammad Ali come to mind.
For those of us that have chosen to tempt fate I still believe in PCT. I see the young guys reading this and immediately thinking just stay on (TRT) but the consequences of doing that at a young age could easily be just as bad, albeit different. No, I will avoid TRT as long as I can.
Yeah, I kind of thought the same thing. I'm very pro PCT. I may delete this just because I really don't want these young guys using it as a reason to castrate themselves. But just wanted it here as something to think about.
I agree with Grimey, leave it up. Hopefully if they do get the idea they still see us saying no..
Dont delete it Ed. If someone is daft enough to use this thread to justify TRT at a young age thats just natural selection doing its thing. Its an interesting topic.
X2 if guys my age are ignorant enough to do TRT because they read this then they shouldn't have ever touched gear. People will do what they want and find any excuse to do what they want, maybe they will try and use this as an "excuse" oh well it's on them.
That's why knowing when to start you pct is imperative.
That's really scary. Almost makes the old school taper/pyramiding method seem like a good idea. Atleast you won't be dropping from 4000+Ng:/dl to 0 it could be a much more gradual drop off with a taper.
I don't know man, perhaps.. Perhaps taper down to normal levels, and then doing what you can to get the nuts kicked back on as soon as possible.
I'd be interested to hear Vike Chime in on this, to see if he's noticed Parkinsons in juicers in all the years he's been juicing.
Thats interesting But I would rather focus on the enlarging of the heart and Problems similar to that You know the thing that actually happens and kills a lot of bodybuilders at 30-40-50 years old =)
Genetics pre disposition(Hopefully used the right term LOL) is to blame for many diseases
boatriderAgree. I bet that has a lot to do with crazy GH levels and pain killers
Makes total sense on a scientific level
Testosterone goes up - Dopamine goes up.
Testosterone goes down - Dopamine goes down.
(broadly speaking)
Parkinsons is partially contributed to the degeneration of dopaminergic neurons. Dopamine acts as a neurotransmitter and is responsible for cognition and motor functions amongst others, (hence the type of symptoms experienced by sufferers).
See the link here?
(I apologise for going into science geek mode)
Lol, never apologize for going into science geek mode. That's my specialty when I'm not killing hookers.
I wonder if doing a test prop taper at the end of cycle to steadily lower levels would make any difference.
I don't know. I doubt it. there has to be that point when you cut it all off to kickstart the natty again.
boatriderMaybe the less time test iscut off the better. On another note test e levels would fall slower
I disagree. I think the goal would be to get natty back in line as fast as possible. Start cutting time off time and every cycle it will get harder and harder to recover.
boatriderThat's the prop idea. You only go 3 days with out pct.
Squished just like a fkn bug!!.............................. eat this sucka!!
Wassup big V! I was just starting to have fun with the little fella.
Hey while you are here...
You have been around the BB scene for longer than anyone I know... Have you noticed above normal Parkinson's cases in the circles?
Nah............ in Britain we dont have the same problem bro because most guys here believe in the thoughts of "if you are ON you are ON............ Why hammer the body to death by keep booting and re-booting by cycling?.... PCT is old hat.
But!... whilst i am here i will rip the lid off a can of worms thats been bugging me lately... regarding the statement we hear every day here "be the turtle! the turtle wins the race!"......... REALLY? the only race a turtle will win is a fkn turtle race!!........ lmfao!
You know what i mean! safety first blah blah blah for 20fkn years to change nothing........ Anybody with proper guidance and strict protocols can come from NOTHING to stage ready when they take onboard RACEHORSE tactics.
Any turtles here fancy a race with me?............ fuck the turtle theory inside out im sick to fuck of reading that statement.
Sorry for changing the topic im in a wicked mood tonight.... i am overly impressed with my recent choice of gear its like going back in time lol
No need to apologize. That right there is why I have always liked your posts and opinions.
Lmao. Where I come from, a turtle is when you have to shit really bad and you can't find a place to drop it and the turtle starts to peak his head out. I know for a fact that when you are turtling you aren't going to win any race unless it's to the shitter.
On a side note.... Now that I know that you hate the term "Be the turtle" I'm going to use that shit every day.
ok i have no probs with that bro.............. i have to go i have a hot chick dangling offa my sexy nerve in off topic! seeya later she is better looking than you lol
But bro, you said I was the only one!
Maybe if u would get the eriod van cleaned up. The smell of dead hookers is overwhelming
God I love the way you think. I think I'm gonna move to Britain. I wish you write more bro not trying to nut hug here but you speak the truth.
YOU my son............ are now the proud owner of some of the best gear on the fkn planet, use it well bro it will result for you........... i have actually shuttered my dosage down its thats fkn good!!
That's exactly what I wanna hear. I won't be going anywhere else from now on they're to good to me and the gear is fucking fire. I have a ton of there gear right now and I have the stong urge to hoard more.
boatriderThat's is a original thought. Lol joke
Benny BlancoYou must really like riding boats
boatriderAnother reason a prop taper should be included in every cycle including the 1st.
boatriderTo the dick that begged this. Fuck you this I a great idea
Benny BlancoWho's begging you?
boatriderLol fuck you I screwed up
Dear Dickrider,
If you are going to hijack my thread at least try to spell the easy words right. I would also appreciate it if you would complete your sentences. I don't think that I'm asking for too much here.
I realize that you are more than likely mentally challenged and I'm cool with that. However, as a mentally challenged person, sometimes it's important to know your role and shut your mouth.
All my love, no homo
Ed.
My mom has had Parkinson's for quite some time and I know quite a bit about it. Never heard the testosterone link though. Never thought about teatosterone since my mom has it, but it's interesting since Parkinson's may have a genetic link that can be passed on. I'll look into it.
That being said, Parkinson's is a nasty, debilitating disease. If there are any steps we can take to lesson our chances of getting it, they're worth investigating.
Yeah, I thought it would be something for all of us juicers to think about.
Tink22Nvm
Yea, something to think about. But unlike castration we are only low , low T for a shirt time , providing we are using proper pct meds.
my doctor actually told me something similar to this when I had my boys removed. he said that it does put me a greater risk of Parkinson's but since it does not run in my family he said the elevated risk was minimal.
Lol you mean you had a vasectomy or did you actually cut you boys off?
Cut off had testicular cancer
boatriderNever been a troll before
U deserve every bit of it u p.o.s.
Oh I see.
boatriderThe man is all frank. No beans
U dont joke on that shit!!!!!
boatriderIt was not a joke. It was fact.