+ 6 Proviron: busting the myths
Well; I did a lot of research on this fascinating product to find out that most of the broscience you hear is completely false and also the placebo effect is pretty high with people. Let's get into the details a bit shall we?
Trials
In one small scale clinical trial of depressed patients, an improvement of symptoms which included anxiety, lack of drive and desire was observed.[2] In patients with dysthymia, unipolar, and bipolar depression significant improvement was observed.[2] In this series of studies, mesterolone lead to a significant decrease in LH and testosterone levels. In another study, 100 mg mesterolone cipionate was administered twice monthly. With regards to plasma T levels, there was no difference between the treated vs untreated group, and baseline LH levels were minimally affected.[3]
Mesterolone is the chemical name for Proviron. It is a very interesting anabolic though it's use in bodybuilding has very little value. The most common reason to even consider including it in your stack is for anti-estrogenic activity. Before the use of SERMs like Clomid and Nolvadex, this product was beneficial.
An amount of AAS slightly over the amount that would be manageable without Proviron became tolerable with it. However, the effect is indeed very marginal, and much better anti-e's exist.
The most common reason this is used is to "boost" your libido. It is true that when added to normal androgen, it does have an androgenic effect that improves libido. Bear in mind that AAS has the same ability. In a cycle, adding Proviron accomplishes nothing. Such as in the case of Deca which may affect libido, Proviron provides no greater help against that than do various other AAS.
One of the interesting things about Proviron is that while it lowers shbg; it is virtually useless for building muscle.
Contrary to common belief, Proviron is inhibitory of the HPTA. Using it during the recovery phase as part of post-cycle therapy is counterproductive. Occasional recreational use presents no problem.
Proviron sometimes is used in female bodybuilding, but it almost undoubtedly the worst ratio of anabolic effect to virilizing effect of any anabolic in use. The value is in fat loss and “hardening,” but obviously there are better choices. Most of that is from anti-e effect, which Nolvadex can accomplish. And for an androgen component, there are better choices, such as Primobolan.
Proviron is not hepatotoxic, as it is not 17-alkylated.
Tablets are typically 25 mg, and taken one or two at a time. Amounts greater than this have no further effect on improving libido off-cycle.
So there you have it. Placebo effect while using this product is very strong in people; it's amazing what your brain can do when you convince it. More reading can be found here. So many sites and (sources) glamorize this product and to be honest I think its only to sell it. I fell victim to the placebo effect myself. The more you know the better you can prepare for what's ahead of you. I want you to dig deep and read some of the studies.
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You might have missed the point a little.
Lol. Yeah? Enlighten me.
Proviron takes a week to 10 days days to reach blood concentration according to my Endo so after 3 days you feel a difference then tell me again about placebo. That's what I meant.
The active life of proviron is 12 hours. As an oral drug which is released in to your system starting immediately...what exactly are you thinking 10 days will change about the blood concentration? It has a 12 hour terminal half life as stated by the Bayer brand themselves. That's like saying dbol builds up in your blood day after day. If that was the case you would end up with blood levels far too high.
If what you are saying is that it takes about 10 days for you to have a noticeable effect than you are in fact admitting that the drug has a noticeable effect and the placebo wouldn't make sence.
Read through all the posts please. Anadrol has an active life of 8 hours but that does not mean it goes to work immediately in 8 hours. Blood concentration is key here. Like all orals. And even Injectables. I'm not trying to turn this into a pissing match between you or anyone else; I'm trying to educate like 90% of my last posts. Maybe my Endo is an idiot and has no idea what he is talking about; but then again this is his specialty and I can only hope he knows a little about what he prescribes.
And yes....anadrol does go to work immediately. You just may not notice it for a few days. A lot of people will start to retain water on day 1! Obviously something is making that happen.
Endos are not trained for even one day in the things that we do. I understand a post for conversation but orals and injectables are very different. Orals do start to work immediately. Maybe you can't see it on day one but it is attaching to receptors and beginning the processes. Blood concentrations of Proviron reach maximum in like 1 hour. Injectables would be much different unless they are no ester.
Have you used pharm grade before? I've never used it before my self but a lot of people including many vets on this site swear by it, and there very adamant about how much different pharm grade is then stuff put out by the ugls.
About it being usless for muscle building , well there's no doubt that by itself lots gonna gonna build muscle, but it's proven to help free up testostrone bound to shbg which is extremely benifical. Free testosterone is the only thing that's benifical for building muscle, so the more you can free up the better.
I have used both bayer and prescribed by my doctor. The shbg lowering effect is so minimal that it is almost useless. You are better off taking Tbol or even Anavar if that is what you are after. A lot of people will swear by it; but they are using it in a cycle or stack that already provides the same effect but to a greater degree. Nolvadex works better at increasing your free test and libido then proviron; my Doctor told me the same thing. I met with him on friday to talk about how things were going with my therapy and we talked about it. He prescribed me Nolva even though I am on trt and I grilled him on why Nolva instead of proviron. I wish I never did after listening to him ramble for almost 30 minutes. I lost my drive and I was taking proviron. I started taking the Nolva and it is starting to get better. 10mg a day he said for a week then drop to 10mg for another week and then take a week off. rinse and repeat. As far as rebound my E2 has always stayed consistent and never reached critical even on a heavy cycle....but I use adex @.25 e2d on those times.