Extreme PIP first injection Test E 300
UPDATE: drew .85 ml of test e 300 for second pin in opposite glute. Ran syringe under hot water for a minute or two. Injected slowly ~ 1 min. Swelling is much more localized as compared with first pin which is still swollen half way down my leg. I have 3 days until that side is up to bat again so hopefully it’s good to go by then. Trained legs yesterday hopped up on some OTC pain meds and had a good workout. This second pin felt as I was expecting injecting virgin muscle to feel, painful but manageable, I think it came down to technique on the first one and maybe a slight reaction to the gear. I’m going to stick it out with this lab since I have 8 vials and hope for the best. Bloodwork week 4. --
First cycle and injecting into virgin muscle. One pin down and the PIP has been rough. Reliable source but I have been told they dose high. Planning on running 500/wk for course of cycle. First shot consisted of 250 mg into glute. I definitely injected too fast I’d say ~ 10 seconds max. I plan to heat the test next time around and maybe split the dose between my delt and quad just to see if that does anything. If that doesn’t work I was thinking of diluting the injections with GSO. Currently I have had flu like symptoms for 3 days and extreme tenderness( hard to walk without ibuprofen). Any other suggestions would be much appreciated.
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UPDATE 2
GSO dilution 1:1 seems to do the trick . PIP much more manageable. Decreased dose per injection .5 mL of Test E 300 per pin. Now pinning 3x a week with diluted dose. So far so good.
I wouldn’t pin that other glute again yet. Need more locations so more recovery. Hit VG’s, lats, delts or quads as last resort. For me VG is best site to pin along with glutes
I should have been more clear. I’ve only been doing VG injections but the swelling has moved into the glute on one side and up my back on the other. It’s a damn ordeal. I’m going to split this weeks 500mg in to 3 different injections and hope the reduced volume makes it more manageable until my GSO shows up.
That sounds extreme. Do you have test from another source to try just to make sure it’s not that particular brand that’s messing you up?
Same thing happened to me. Some brands did more than others, but even at about 2 years in I’d still get pip most of the time. For me personally what got rid of it was first warming the gear up a bit before injection. Second, was actually switching esters. 90% of time no matter what I did or how careful or whatever I was, Test E would ALWAYS give me pip for example, when I switched to test C…Never again no matter the brand. I’ve been told the two uses different carrier oils in most cases and just happen to respond better to one over the other.
Did your PIP get more manageable the more you used the test E or did you switch to Cyp pretty early?
I always had some pip to varying degree no matter what Enanthate I used or length of time. Some did better than others, but for me, nothing ever really made it go away. I switched to C about 2 years in, give or take a few months. I was just dead set on using E for whatever reason. C has been a game changer for me personally.
you're officially in the "My ass hurts so bad I can’t sit straight" phase of your first cycle , congratulations! You're not dying, you're just learning.
Here's What Happened:
Test E 300 = high mg per ml = thick oil + more solvents
First time in virgin muscle, injected way too fast
Probably not deep enough or smooth enough
Combine all that---- You just pinned a chemical chili pepper into your glute. PIP (Post Injection Pain) is expected, but this sounds like you did the full buffet.
How to Fix It:
1. Slow down
Your injection should take 60-90 seconds, not 10. That oil needs time to disperse.
Rushing it is how you create an oil pocket and piss your muscle off.
Warm the gear
Running the syringe under hot water = solid move. You did right there. Thinner oil = easier flow = less trauma.
Massage the site
After pinning, massage it like you're trying to bribe the muscle to cooperate. Then walk. Don’t go pin-and-plop on the couch.
Alternate sites
Quads are hit or miss — some love it, some feel like they got sniped. Delts, Better. Glutes, Classic. Rotate them. Give your tissue time to recover.
Split the dose
Injecting 250mg in one shot of 300mg/ml gear is a spicy meatball. Try splitting it to 125mg in two sites if needed.
GSO cut
Cutting with Grapeseed Oil (GSO) is fine — just make sure it's sterile, not from Whole Foods. You can do 1:1 and bring the mg/ml down to something your glutes don’t consider an act of war.
Welcome to the “Test Flu.” Your immune system thinks you're under attack — you're not. It's usually gone by Week 2. Keep training. Hydrate. Ibuprofen if needed.
Real Talk: You're on your first cycle and already pinning Test E 300?
Bro… that’s not beginner-friendly gear. Most labs dose Test E at 250mg/ml for a reason. Anything over that means more solvents (like benzyl alcohol), more injection volume, and more pain , especially for first-timers.
If you're gonna keep running it, fine. But don’t be shocked if every pin feels like punishment for skipping leg day.
Do you think I may get more used to it or does it sound like a reaction to the ingredients to you. Like I said I have 8 vials of the stuff so it will kind of suck if I have to reorder from a different lab. I received 100 dollars of store credit since they sent me the wrong gear…… I ordered 10 vials of 250 test E and received 9 vials of 300 test E from a different lab. Wasn’t too concerned until this PIP. Thanks for the thorough response !
Totally get it, and yeah, you might adapt slightly as your muscles get less “virgin” to oil. But let’s be real: 300mg/ml Test E is spicy gear, and most guys don’t magically stop feeling that post-pin haymaker just because it’s week 4. What you’re probably reacting to is the solvent load, too much BA or BB, which is common in overdosed gear. That’s not something your body “gets used to,” it’s just tolerating chemical warfare better.
You got sent a hot batch, basically. Not your fault. But:
You’ve got options:
Cut it 1:1 with sterile GSO and bring that 300mg/ml down to a smoother 150mg/ml. That'll save your glutes and stretch the vials. Win-win.
Split the shots into 2x per week, smaller volumes in better sites (delts, glutes, even VG if you're confident).
Pin slower give that oil time to disperse. Literally count to 90.
Warm every shot, every time. Warm oil = thinner oil = less trauma.
Also, props for not rage-refunding when they botched the order. Most would’ve lost it. I would have!!!
You’re not doomed, you’ve just got eight vials you need to take slow with and more prep that's all. So warm it and split it into two shots a week or 3 to get closer to that 500mg a week so 450mg, just take your time.
I went ahead and ordered some USP grade filtered GSO and plan to dilute 1:1 the GSO will be arriving in 5 days so my plan is to just pin 3 times this week at a decreased volume to hopefully minimize PIP. Once I can dilute I will still stick with the 3 pin per week schedule to accommodate the increased volume needed to get close to my planned 500 mg per week. My only question is how do you mix the solution in syringe? I assume you just give it a few spins and twirls, heat it up call it a day? Again, thanks for the help!
You’re doing it right by ordering USP-grade filtered Grapeseed Oil. Now let’s break down how to mix and inject with zero PIP and max effectiveness.
Step-by-Step Mixing & Drawing Technique
Draw the GSO first
Use a clean syringe, draw your sterile GSO (e.g. 1ml) from a sealed bottle
Draw the Test E second
Pull your gear (e.g. 1ml of 300mg/ml Test E) into the same syringe
Total volume = 2ml , dose now at , 150mg/ml
Swap the needle
Use a small 25G or 27G needle for actual injection
Keeps the oil flow smoother and injection less painful
Mix it gently
Roll the capped syringe between your palms for 30 to 60 seconds to mix evenly
Do NOT shake!!!!!!!!!! shaking introduces bubbles and irritates tissue
Warm it before pinning
Place the capped syringe in a warm water cup or between your hands
Warm oil flows easier and cuts down on PIP
Pin slow
Goal: 60 to 90 seconds to inject 2ml
After full injection, wait 10 seconds before pulling needle out
Massage the site
Gently massage the injection area for 30 seconds to disperse oil and reduce knots
Resource You Can Watch
“How to: Mix/Dilute a Vial” , clear tutorial that demonstrates the correct way to mix oil and inject hormone solutions. Great visual reference for beginners and veterans alike.
https://www.youtube.com/watch?v=EuxuO6aqHo8
Guide to Diluting Testosterone 250mg/mL to 50mg/mL
https://www.reddit.com/r/TRT_females/comments/1f6a70y/guide_to_diluting_...
You are extremely helpful, It’s much appreciated. Someone give this man a raise! I’ll keep you updated on the adventure.
Does heating the oil effect it at all?
No, if you're thinking it'll break the compound or something like that, you're overthinking it. Heating the oil won’t damage anything. You're just bringing it closer to body temp. That means better absorption, less pain, and smoother muscle adaptation. Simple.
Could be EO and u just react bad to it. Can just be the b.a. only way to know is try another lab. And know what's in it.
The box reads 300mg test enanthate, benzoate 0.3 ml, benzyl alcohol added as preservative, 9.45 mg MCT. If you were having a reaction to this particular blend what would you personally look for for your next lab?
300mg is a tad higher in concentration than 250 which CAN play a part. Some people don’t respond as well to different carrier oils. With that said, my guess is it’s virgin muscle. My first pin (delt) felt like I got legit shot in the shoulder. I don’t really know the science behind it but it def is a real thing anecdotally
Yeah I’ve got a sore donk for sure. The pain I can suffer through the swelling down the leg is not cool.
Nice username, lmao
lol, that’s right
That type of muscle tissue will not grow with peds!!!
Naysayer!
If it keeps happening stop use and go to a different source. It can be the type of oil they use. I cannot use the brand that has a lizard that shoots fire because every time it would feel like fire shot into my muscles and I would be so sore for days. I switched and have not had an issue since then.
I gave it another go tonight in the other glute, same dose, warmed the oil this time and injected at a slow rate. I have low hopes but fingers crossed. If it comes back (the pip) the same way I think I will try to dilute first then if that still doesn’t do it switch it up sources. Ibuprofen does the trick but popping 800 mg x 3 a day seems bad.
I would try to avoid ibuprofen and other nsaids on cycle. It’s been shown to negatively affect protein synthesis, ie muscle growth. Use tylonel instead.
It will be like this for at least your first 2 cycles, as you have already stated its Virgin muscle and has never been injected with synthetic testosterone before or any other compounds for that matter. All part of the fun of running steroids. Its not as easy as simply injecting for a blissful 4 weeks and then all of a sudden you have gained 30lb's of muscle and you can call yourself an 'Online Steroid Influencer' Lol
I’m just trying to be able to regain leg function to be honest.
Ranger3252Virgin muscle, wait until you pin your quads for the first time. Get that pimp walk on! I’ve been pinning for over a decade and was using this EQ test 400 mix and I felt like it was my first pin Every-time I injected. It was solid gear just highly concentrated. 300 mg per ML isn’t anything crazy. You will get use to it. Cut it with something less concentrated that you have on hand.
I was thinking of ordering some GSO and giving that a shot. Next pin is tonight and I’m not looking forward to it. My supplier sent me the wrong brand and concentration but I decided to go with it after a little research. The brand is B****** and sometimes the B looks like a D.
Ranger3252It will get better we all went through it. Honestly with virgin muscle you just need to stay the course. Now you could be in my situation and have so much scar tissue I can’t even get a flu shot at work because the nurse can’t inject through the scar tissue lol, always takes them a few tries.
After getting Bronchitis this year for the first ever time I am never missing that Flu vaccine again!!
Ranger3252That’s why I have the nurse keep trying lol. I can’t get sick and not be in the gym. I swear some of these normal ailments are getting worse since Covid vaccines.
It gets easier over time and less painful. However, you said you might split it between delt and quad. I definitely wouldn't pin quads if you're trying to stay away from pip. Some people like quads, but I personally dont. It can be quite painful. Glutes and delts for me.
Heating in hot water, heating pad, hot shower first, none of them things worked for me. Grab a bottle of something extra you have and mix .5ml in with the test or go online and order some gso and mix in .5ml. pull plunger fully down and roll, do not shake syringe and inject every single time PIP free. Use .5ml of tren, eq, primo, deca or whatever you have and you get double benefit
18ga draw ruins stoppers and can get bitz into injection oil.
Whats the concentration?? Mg per ml
Uh oh. Same as irongame, I got them from trt doc and then bought like 200 of them... I haven't had any problems yet but maybe I should ditch em. What do you use to draw? 20ga?
I use a 23G to draw and 25G to inject with no issues.
Theres online sites with eaze. Like 35bucks per 100 big pins. Or 20 for 100 slin pins. I draw and pin. I just never got into switching pins. Its together and sterile so i go that route. Nothing wrong with switching for sharper pin.
https://www.eroids.com/forums/general/general-talk/needles-and-barrels
First cycle pip is kinda normal. After you get your personal knowledge down...technique etc....its easier
300 mg/ ml
It sure does. My TRT doc prescribed me 18g harpoons to draw. Only ended up using them a time or two and it ruined the stopper and wasted over half a 10ml vial of test.
Make sure you wipe the vial top and your injection site with alcohol swab and let dry first. Make sure you pull back on plunger before pushing oil in, to make sure no blood comes out, means you went thru vein, if so need to start over with fresh everything. Heat oil (like you said) and inject very slow. Dunno how long everyone else spends pushing oil in but about 90 seconds for me. What gauge needles are you using? I use 18ga to draw and 22ga to pin. i heat the oil with the draw needle and cap on and then switch to the 22ga so no water contamination. ---- but also you say this is your 1st cycle/1st pin and doing 500 test/week. That's a LOT for a first cycle. Hopefully some of the pros here can chime in, but you should be going for the lowest effective dose and in any event be titrating up to a dose that high. also you didn't say anything about blood work or any other plans for your cycle.
I have 18ga to draw and 1” 25 to pin.
What is your preferred heating method?
Personally I load up my vial with my draw needle, put the cap back on it (luer lock) and then heat it under hot water, then I wipe it dry, change to the 22ga, push some oil up to push the air out of the fresh needle and then pin. Not sure if that's the right way or if doogie howser would approve, but I went from getting PIP like you to zero PIP. You should definitely reach out to some ppl on here about your cycle plan and blood work etc. I've never run a big boy cycle, just high end trt doses and a little mast. I am not qualified to give you advice on your cycle dosing, but it does sound a little poorly planned and dosed pretty high. @Jockstrap @irongame427 @press1 come to mind about guys that would know
A candle/coffee mug warmer works well for heating the vials, too. Like 5 minutes on there picking it up and swishing it around gently a few times and you're golden.
@Milfpounder the ricebags for sore muscles is better for warming. Water of any type has possibility of microbes. Agree it sounds like high mg gear
Oh hell ya stopping by the store immediately after work for those. Thanks man!!!
I draw with a 21 or 22g. Even a 23 if that’s all I got. 18g is too big and will damage the rubber stopper on the vial. For injecting the biggest I ever pin with is a 25g. 22 is way too big. does too much damage to the muscle. I use a 25g 1 inch for glutes, only because 27 or 28g 3/4 are really hard to find. 27-28g 5/8 for delts and quads. Need to be relatively lean to use a 5/8ths.
I don’t heat anymore. Used to when I first started. It’s been so long it’s hard to remember but I think I heated the syringe with warm tap water. Don’t get it on the needle though or it will no longer be sterile. Heating pad it’s probably a more sterile method.
So just trial and error for the PIP? Do you suggest giving the other injection sites a shot or just assume the new muscle is going to hurt while my body adjusts?
The first time you shoot a muscle it’s going to hurt. I distinctly remember that every time I tried a new injection site. So if you put that stuff in your quads, you’re really not going to be able to walk lol. And if you put it in your delts you’re not going to be able to move your arm for a while. Those two spots for most people are worse than glutes in terms of pip.
Given what you’re doing you can basically do just glutes and since you’re injecting twice a week each glute will have a full week before it’s time to use it again. Which should be enough time for the Pip to completely subside. The Pip should be less and less with each injection as your muscle gets used to it. Assuming it’s not really high pip gear. Someone new to this will get pip from the smoothest gear in the world that doesn’t give an experienced user any pip. But some there’s some formulations that will cause pip regardless of experience. You may have some of that gear. Or it’s just because you’re new to this. My last bottle of test C from the local compounding pharmacy for TRT gave me PIP every single shot. And these are tiny shots too. And I been doing this a long time. But not bad pip at all.