posted Fri, 01/05/2024 - 23:28
273
+ 3 Yk11 Induces Oxidative Stress and Dysregulates Mitochondrial Function
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Yep, I'm not taking this ever again....
https://www.sciencedirect.com/science/article/abs/pii/S096007602300119X
From the article - "The administration of YK11 resulted in alterations in the endogenous antioxidant system, promoting increased oxidative stress and proteotoxic effects, impairing all mitochondrial function markers in the hippocampus."
I don't know exactly what that means in terms of effects, but I know it isn't good. Yikes!
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Have you ever tried LGD 4033 mate?
Acid methyl ester
Neurological,liver,heart damage
No thanks
Doesn’t sound good whatever it means
Yeah, I'd been getting good results but no thank you! Just judging from context clues, I know increased oxidative stress can reduce the effectiveness of antioxidants, which help control free radicals that cause cancer. So that's bad.
And the mitochondria as we all know from school is the powerhouse of the cell. Probably a good idea to keep the power supply to your hippocampus working properly. Hippocampus is involved in learning, memory, and emotion. Guessing it can have negative impacts on those things.
I will just stick to my test, deca and HGH I guess!
Sounds like you're knowledgeable about these things just like I am. Yes my brother I would definitely stay away from this stuff. Alot of these compounds are half way researched if indeed there is any research. Nah I'll pass. Wise decision my man. Disruption of mitochondria...not good. @Rosschestzip something always told me to stay away.
Ya I’ve always felt uneasy about all of those sarms(basically research chemicals). We know the risks of the old stuff and how to deal with the negative stuff but it’s a whole new set of issues with the new stuff. I feel the same way with a lot of things like vaping vs cigs, and heroin vs fentanyl. We know what cigarettes and heroin do and how to treat the bad stuff from it but all these new crazy chemicals are a whole new beast. The evil you know is better then evil you don’t know
I couldn't of said it any better. I feel the same way. I always had a bad feeling about sarms.
Yes I believe your right about oxidative stress can lead to cancer but if I remember correctly I think it also is speeding up cellular aging, or just aging in general. So to me this is basically saying yk-11 will make you old and grey, and fuck up your organs and could give you cancer? But the problem with studies like these, to me, is that there’s no real quantifying the risk. We all know there’s some risk involved with a lot of the stuff we take but my question is how bad is it. Is it like smoking cigarettes, meth and drinking Jäegermeister all night bad or is it like occasionally eating McDonald’s bad? BUT the fact that it’s a fairly new substance plus this study means I’ll more then likely be staying away from it. The tried and true stuff works for me
I've been looking into this sarm quite a bit. Good info.