posted Wed, 09/28/2011 - 21:34
1949
Splitting Your HGH Dose
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I'm getting ready to start my first round of GH pretty soon, and I had a question about how to dose it. My guess is I'll be sticking to around 4iu/day, so is it better to hit 2iu 2x per day, or just hit 4iu right before bed?
I know people who do things like hit half their dose before bed, then wake up in the middle of the night to pin the other half. Just wondering if there is any benefit to a split like that.
Thanks!
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I would actually recommend splitting the dose into 4 x 1iu shots. Numerous studies (which have been conducted in rats and humans)have shown that a pulsatile pattern of GH delivery is what the body responds to best. Delivery method of the HGH is also a factor, with sub-cutaneous being the worst way to administer it. Intra-muscular is slightly better as it releases the pulse more quickly and clears a little faster before starting the next pulse. I.V. administration has proven to be best as it releases and clears the pulse quickest, enabling you to administer a pulse of HGH every 2-3 hours. Using HGH this way has been shown to be roughly 3x more effective. So instead of getting 4iu of HGH, it would be the equivalent of 12iu. Pulsation has also been shown to be safer as it mimics the body's own endogenous GH secretion.
http://ajpendo.physiology.org/content/283/5/E1008.full
Be done with all injections at least 6 hours before bed
Just take it all in the morning!
I have heard many say to take it all right before bed to avoid the lethargic feeling during the day - what's your feeling on that?
tread-mI've never had a lethargic feeling on hgh?? As to at bed, for men you pulse hgh at night and using growth does not fully shut you down. However, popping at bed time could suppress any natty pulse so I'm a mid day guy myself. For women, they pulse awake during the day so a pop at bed time makes sense to me.