+ 5 Higher dose HGH and it’s effect on blood glucose levels
So over the past few weeks I’ve spoke with a few guys about hgh’s effect on blood sugar. It’s kind of accepted that hgh can cause higher blood sugar levels. The way I understand that this happens is that the hgh reduces the effect of insulin therefore making it harder for your body to break down sugars and leaving more sugar in your blood stream. BUT igf-1 has been shown to basically do the opposite and lower blood glucose and increase insulin sensitivity.
When I would take an average dose of hgh (3ius) daily for a period of time, my blood glucose levels upon waking would increase, on average, by about ten points. (Started-93, on hgh-103). Than a few months later us was using higher doses(8ius) and I would occasionally notice that sometimes after a large dose I’d feel weak and almost like a mild hypoglycemic feeling, which is technically the opposite of what I’d expect to feel.
So now I was confused and spoke with some guys and some had experienced this same thing. The basic explanation that was agreed upon was hgh causes insulin resistance and igf-1 causes insulin sensitivity, when taken in a larger dose your getting more of that igf-1 conversion so more insulin sensitivity. Yesterday I decided to do a little experiment and did 7ius in one injection and measured my blood sugar to see what happens. Here it is:
6:30 blood sugar - 141
6:30 inj. 7ius subcutaneous
6:40 blood sugar - 140
6:50 blood sugar - 146
7:00 blood sugar - 116
7:15 blood sugar - 112
I think the reason I didn’t get that mild hypoglycemic feeling was because my blood sugar was so high to start. If I had started at 110 and dropped 30 points I wouldn’t have been feeling as great.
This was just a really simple and quick test, and this is just how MY body reacts to hgh so yours could be entirely different. I’ll keep y’all posted with anymore data I gather as I test this and also would like to figure out for 100% certainty the relationship between liver health and hgh, so any data I gather on that I’ll post as well. And if my interpretation of how hgh actually raises blood sugars and how igf can lower it is incorrect, please enlighten me below or msg or whatever
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I’ve been on growth for 7 months now, between 4-6ius and my last two fasted blood tests put my glucose at 77 and 78mg/dL respectively.
For some reason Tren is what really messes with my glucose levels, every time I’m on my fasted glucose is 101 and I experience episodes of going hypo on occasion. Although it’s been well over a year now since I have used it, it’s something that has consistently happened over the last decade of using it.
Is your fasting BG really 141? Gotta get that under control. Many options: diet, cardio, lifestyle, drugs, et cetera
Lol no that’s insane. It’s not fasted. That would be like type 2 diabetic. Well not really, but at the very least pre diabetic. That’s was after eating a snack and then what really made it so high was drinking a Gatorade. My problem is actually my blood sugar going too low. I have a hard time keeping it over a 100 without just eating pure sugar. I was actually shocked it was that high when I started this, but figured that was good time to try this just to see if it tanked or what.
Wish I knew more to weigh in on this but I don't. It has me really interested though. Appreciate the write up and look forward to what others have to say.
Thanks bud. Just keep in mind if your gunna be using hgh, these results aren’t typical for everyone, I seem to be having some type of sensitivity to the glucose changes, more than the average person. I’m trying to get to the bottom of why I’m effected this way. It could be the hgh, my liver, my pancreas, my diet or just simply genetic. I’ll figure it out someday so stay tuned!!
I actually did just start a week using GH. That was a big reason why this caught my eye and had me interested. I've done research on it and read prob quite a few hours worth of information on forums and medical stuff on Google. This is another to add to the list now. Really anything on exogenous hormones and reactions they have on everyone catches my interest. I've been like that since I was a kid with anything that's put into our bodies (healthy and unhealthy) and the effects it has. Almost like every action has a reaction scenario lol. I'm going way off topic but hopefully everything health wise liver, pancreas, etc. are all good with you and figure an answer out soon.
I’m the same way man! I love pharmacology and all that kinda of stufff, I really wish I were to school for something related to it. Even when I was big into drugs I was researching how the drugs worked and combinations and how they worked on receptors and everything. It’s just all so intriguing to me
Lol dude I've thought the same thing even when I was into drugs. I love pharmacology too. Wish I didn't like taking them as much as I did. I use to deliver for a pharmacy and it was a mess but I also thought I would be an awesome pharmacist lol. So I kinda took a note of what you did and this is what I got.
10:27am-61ng
3.3iu hgh
10:37am-47ng
10:47am-54ng
10:57am-70ng
11:07am-72ng
11:17am-74ng
I ate 7 eggs and 2 slices of toast and 20min later it was 85ng
I think I have low blood sugar and explains why my mornings have been so off for awhile now. Can't get my thoughts together and dropping shit first thing and for a bit after I wake up.
That’s crazy we had complete opposites. Mine went up a tiny bit and then dropped. Yours went down a tiny bit and then went up.
Now yours is the response I think most people have, in that it raises it, but I’m just baffled why mine tanks!!! So it seems like igf-1 is what causes the drop but hgh itself cause the raise. So for some reason maybe I’m converting more of my gh to igf-1??? Or it could just be 100% dose related. I gotta get my blood work done and test my igf-1 levels and liver markers. I wish I was a millionaire, I’d be doing bloodwork everyday lol. I don’t really have the cash to pay for the test right now, so I’ll have to wait like two weeks unless I can find a way to get my insurance to pay. I’ll tell them I think I’m shrinking and need my gh levels tested to make sure I didnt catch dwarfism lol
Lol that might work. I tried getting my doctor to do it and he said they don't really test that unless it's for short stature or for some other medical reason that may be related to igf-1. He actually said bodybuilders too. I was surprised when he said that. Then he went on the whole steroid rant and how they're terrible for you. I haven't told him that I have taken anything. Think he's suspicious though. Had a male hormone panel done and the cap was like 1600 I believe and I maxed it out. I told him I was trying SARMs and maybe that's why. I said it "legal". Idk if he bought it though lmao. The liver markers might be something and has me interested my AST and ALT were pretty high back in early March. I'm thinking about get the CMP done myself because he won't do one so soon again. It's like $40-$50 on Ultra labs. I like to check my markers every couple months when I'm running then when I cruise I kinda fall back. What do you believe the liver markers are doing? High markers mean igf-1 goes down and normal markers raise igf-1?
It’s a theory I had, I’m sure I’m not the only one to ever see the relationship but there’s zero data on it anywhere. Anyways, when your body naturally releases gh the liver responses by excreting igf-1. So I was using a good amount of gh and wasn’t having any side effects I usually have, at the time I knew my liver was all fucked up, I had been gobbling up orals for a few months. So I figured if the liver can mess up natural release why wouldn’t it effect the release when taking exogenous hgh. I hadn’t confirmed it with my own blood work yet but another guy on the forum was testing his igf-1 level and basic metabolic panel fairly regularly while trying to test a certain sources hgh and of off his blood work I was basically able to confirm that if your liver markers are elevated your igf-1 levels will most likely be lower. As his liver enzymes came down, his igf-1 level increased while on the same dose and same source of hgh. Now this isn’t concrete proof because it’s just one person but if I can confirm it with mine and maybe one others, I’ll be pretty satisfied that it does in fact effect it.
After, I should write something up documenting it, or have someone else more intelligent and better spoken do it lol. Because as of right now there’s zero info on it on the internet. And forums we post here show up on google searches so if someone was looking for that info they could find it, if one of us wrote it up on here
It actually sounds pretty logical in theory that if your liver isn't functioning right that your igf-1 will be lower. My ALT and AST were pretty high in March and when I just got my baseline results my igf-1 is 79 which according to another member and the article he sent that im not even in the 5 percentile. So I wonder if my liver was functioning fully if I would have been in normal range which according to the article is like 90 something. Really interested into see what you develop on this between you and the other member getting tested regularly. Who knows it might actually turn into a write up some where along the line. Its a really good idea to keep notes and track of everything and see what comes of it.
The science I’ve seen is the insulin sensitivity you gain from the igf is very short lived. The constant resistance increase with poor diet/meal timing is what will fuck up your blood glucose. I’m running 6IU/day and my fasting glucose is ~80+/-3. HGH takes real commitment to the cause. I don’t eat anything 2 hours before/after my pin. Morning pin is fasted, then I work out for 1hr, then shower and get ready/make food and it’s now been 2 hours since my pin. I stop eating at 1900. Pin at 2100. Asleep by 2200. Have a solid eating window from 0700-1900.
People who get fasting or postprandial hyperglycemia on GH should definitely consider strategies to control it. Not good long-term. Many options.
You don’t feel awful at 80? When I’m at 80 within like an hour, I’ll start feeling pretty weak, and if I do any type of exercise at 80 I’m screwed. And are you waking up at 80, not eating, taking pin, then training ? Or are you eating first then waiting two hours to pin then training?
Waking up at 80, pinning, then working out. AM is fasted cardio. Lift in the afternoon. Post pin in the morning I’ve dropped as low as 65 lol. 70 is normal range still. You shouldn’t feel hypoglycemic at 80 unless your body is used to a hyperglycemic state I suppose
If you have good HGH 3iu is all you should ever need and it should always be near perfect levels of blood sugar. That's real HGH designer peptide. Not random bloat molecules lmao.
If it a not supposed to effect blood sugar levels then why is insulin considered almost necessary when running higher doses? And why are you cautioned to keep an eye on blood sugar levels, insulin sensitivity and monitor for diabetes, if there’s no effect?
I pretty much have had the same experience with it as you have. I had blood work done on Tuesday. Monday night at 9:45 at eating a chicken breast and a glass of milk. Blood work had gotten delayed as it was the wrong requisition, so it was drawn about 1 PM Tuesday. Blood glucose was just out of range at 101. . I feel that hypo feeling you’re talking about if I go too long without eating especially to start the day.
About a year ago when I was not on HGH a rheumatologist ordered bloodwork for me about 90 minutes after I polished off a Culver’s double deluxe, small fry and two root beers. My blood glucose level was only 61. Clearly it has an effect. Also, my experience with the long HGH products was bad . I would recommend everyone steer clear of them as is wholly unnatural to have a constantly elevated HGH level. My second. vial in on a long product I started to feel like dog crap. I grabbed a latte from McDonald’s, drank it, and felt like crap. At first I thought they probably just need to clean their machine and it made me sick. But then it happened again. So leaving Costco one day at the food court I decided to drink a Pepsi and a half to test it out that sugar was the problem. I felt extremely weak, sick to my stomach and lightheaded. I was also sweating. I’m pretty sure it was making me insulin resistant. Before the recent bloodwork, I was taking 3.6 IUs from a Geno pin EOD since I am not on cycle or anything and to get it to last but also use it up before 3 weeks of reconstitution. To save money and the effects of EOD use are well documented. If I was on cycle or not short HGH and money I would be using daily.
I’m a little confused, the effects are well documented of EOD but you’d be doing daily? So are you saying there’s benefits to doing it EOD documented , or negative effects documented?
Also just FYI I read a study about how PM dosing should increased gh serum levels and also decreased effect on blood sugar issues, so definitely big benefit in evening/nighttime dosing
Yes that is usually when I dose in the hope that I will sleep a little better. But sometimes I do it before cardio on an empty stomach earlier in the day hoping to burn off a little more BF.
Positive effects documented. One Japanese study I had read and one South Korean. Showing the effects might be better with the same overall amount but EOD. Dugouts probably good for non Asians too
Is it the large dose at one time that is the cause or is it the time between injections, or do you know what the reasoning is?
I would speculate it is the larger dose at one time.