ChemDawg2000's picture
ChemDawg2000
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+ 1 Can injectable BPC157 &TB500 be used nasally?

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Recently I was diagnosed with a herniated/compressed L5/S1 along with a tear in my right hip labrum. I’ve used both BPC157 & TB500 in the past after an arthroscopic meniscus repair with great results. Nothing insane but I did feel as though I healed at a faster rate. My only evidence of this is the fact that I had the same surgery on the opposite knee a few years prior but didn’t use any peptides. Just felt like an uphill battle during rehab and recovery. Crazy considering I was 21 when I had that surgery. But I digress…

Since I’m in this situation again and might need surgery, I was considering branching out and trying the nasal, oral and transdermal versions. I will most likely use a combo of all 3 in order to forego pinning this time around. I’m hoping combining all 3 with produce similar results to pinning sub q.

My main question is if I can nasally spray reconstituted peptides that you would normally pin? I’ve seen pre made nasal sprays online with little to no reviews. I may take the leap and buy premade nasal spray, but before I do, I was wondering if anyone on here had any experience experimenting with nasal peptides, or using normal injectable peptides nasally? In theory this should work considering you can squirt BPC157 directly into your mouth but don’t want to waste my time. If anyone else has experience with this or advice please don’t hesitate. Open to any and all suggestions!

When I figure out if I need surgery or not I will repost my final protocol and update accordingly.

UPDATE:

Got word back from the Doc. Tear is minor enough where I can probably get by on some PT, so I doubt I’ll try the non-injectable trifecta I listed above considering the price. Going to try using a double dose of a topical version from relatively reputable source (hasn’t done me wrong yet). Also going to grab an oral BPC157 since I found one that isn’t crazy expensive. I’ve definitely gotten some weak stuff from this source in the past though. Going to double dose those as well just in case. Regimen will be ingest/apply once in AM and once in PM. Going to skip the nasal spray route since the reviews aren’t too good yet, and all premade sources look sketch. Will report back when I start the regimen.

Not expecting magic here. Just going to share if these alternate methods of administration can speed up the recovery process (which is slated for another 4-6 weeks). Last time something similar happened I was down and out for 8 weeks. Hopefully this time around we can shave some time off my recovery.

*As a disclaimer, I take very long to recover and my system is very sensitive to any and all substances, but I do tend to build up a tolerance quickly. So if there is any effect at all, it should be noticeable at first. To mitigate this I’m going to megadose it a shorter time frame to see if anything comes from it.

strongman's picture

Any of you guys that have a herniated disc or ruptured disc or bulging disc you need to absolutely try “McKenzie method“

I’ve ruptured L4 and L5, and had numbness all down the leg. Also foot drop, which is the worst symptom. I made a full recovery by doing the McKenzie method. It’s too much to explain but there’s plenty of physical therapist that can show you how to properly do this on YouTube. Look up Bob and Brad on YouTube for the McKenzie method And ignore the intro song. It is so cringe lol.

Also, for any of you guys suffering from sciatica, you must understand that squats and deadlifts should be eliminated for the long term. If the disc is actually ruptured, you’re just going to squeeze more nucleus out of the disk every time you load that bar on your back to do a squat, or perform a dead lift.

Doing planks daily with McKenzie method will absolutely correct your herniated disc. It took me several months of doing this and eventually I will made a 100% recovery. It’s been about 5 years now and still feeling great no nerve damage no sciatica nothing.

In a promo × 1
kcidnwoymtaenaci0y187's picture

Glad to hear you don’t need surgery!!

I’ve been holding off on L4L5 back surgery for 4 years now. “Self-medicating” with PEDs to get by, you know??

I’ve been experiencing noticeable muscle atrophy lately. Going in for annual MRI next month.

Hopefully — best case scenario — my specialist will prescribe me pharma grade PEDs!!!

Can I get a ‘Whoa Bundy’?

Makwa's picture

Best to stick with injections.

ChemDawg2000's picture

Yea I know it won’t heal the ligament. Was hoping to take them after surgery to accelerate the recovery process. Trust me, if I had the paper I’d already be on a flight to Brazil for Stem Cells. Have you had any experience with PRP injections?

UncleYoked's picture

BPC, maybe. TB500, I doubt it. With BPC it's a bit of a different peptide with decent bioavailability and it's not super delicate, it can be taken orally but it's not likely going to hit ligaments and muscles as well doing that, if you have stomach damage, then I'd say oral and inj are the way to go. For recovery from surgery, I would personally stick to pinning, anywhere sub q if you can't or don't feel comfortable with site inj.

kcidnwoymtaenaci0y187's picture

My, how times have changed in 2023! People are now using The Wolverine Stack “nasally” ???

But as with most meds….
SNORTING vs INJECTING vs SMOKING vs DIGESTING…
I believe injecting is usually the way to go.

I do not condone any of these actions EVER

Nattyboomba's picture

You can freebase BPC?

kcidnwoymtaenaci0y187's picture

Shooosh!! Don’t give ‘em any more nutty ideas!

UncleYoked's picture

i do

Drexyl's picture

It’s the ether that gives it that nice sizzle.

kcidnwoymtaenaci0y187's picture

BoLo,

I’m an old man now. Trying to set an example for these PED-sniffing kids, you know?

Meanwhile — poppin’ DROL; using 420 all day; and injecting Growth 2x a day

FlemDaddyKush's picture

It depends on the chemical weight. Once it's over a certain weight/mass it can't be absorbed nasally. I forget the exact.number. they discuss this alot online when people ask about whether nasal tesamorelin or sermorelin works and people describe how they are over a certain mass so it can't be absorbed. If you do research you will be able to find your answer. I've only really heard of some people having success with nasal mt2 and it's.not a lot of people saying yes. Bottom line I would just stick with the injectable.

ChemDawg2000's picture

Interesting, didn’t even consider the mass being an issue. I’ll do a bit more digging on the subject. Thanks for the direction!

ChemDawg2000's picture

I’m aware of the negative reviews for premade nasal sprays, which is what lead me to start this topic… Was hoping reconstituting the powder version may work in a similar manner as oral by absorbing through the mucus membrane of the nose. Some brief research stated you can ORALLY take INJECTABLE peptides like BPC157 for gut healing and systemic healing after reconstituting. Thanks for capitalizing a few words man, but I’m looking for advice from people who can give a scientific explanation as to why it won’t work.

kcidnwoymtaenaci0y187's picture

Chem,

What on God’s green Earth made you decide to absorb peptides “through the mucus membrane”???

ChemDawg2000's picture

Haven’t taken the leap yet. Weirdest thing I’ve experimented with in that realm was a topical patch (which was shit) and a topical cream which seemed to accelerate healing but could have been placebo. Wondering if it was even plausible before I start huffing hella BAC water & peptide powders and end up with a sinus infection. Just wondering if anyone has tried it considering they sell premade nasal sprays and there’s been a tiny bit of research on the subject.

kcidnwoymtaenaci0y187's picture

Again…

Injecting > Snorting

Nattyboomba's picture

I have seen a few guides as to how some peptides like PT-141 & I believe BPC-157 can be reconstituted & made nasal friendly, but I don’t have any links or direct experience doing so. I’ll take a look around and see what I can find. I’m curious about this myself. I wonder if since BPC-157 is mostly locally effective - if it would assist in healing the knee or if the healing property would be mostly had in the nasal cavities where it’s absorbed, and never make it as far as the knee. I’ll look into this

ChemDawg2000's picture

I was thinking there might be a way to reconstitute in a manner that would dilute it enough but at the end of the day I’m
no chemist. Hoping it would be as simple as diluting or enough with enough BAC water, but sounds like wishful thinking.

During my last bout with BPC 157 I pinned sub q in my stomach instead of directly at knee and it still seemed to work fine. I know local is best but I was too squeamish shoving a needle near my sutures. Even though the proximity was close to the injury I did still feel overall systemic effect, but I wonder if you’re right about it just healing the shit out of my sinuses if I use it nasally.

I’ll look into ways to reduce the mass of them or of its even possible. Thanks for the insight!

Drexyl's picture

It may be a legitimate option though…

Nattyboomba's picture

Suppositories work in the same way nasal insulflation works; via mucous membranes. There is just many more in your butthole, so when plugging things, it’s absorbed a lot faster than intranasally. So if we solve the nasal route, we can safely say you can boof it, too.

ChemDawg2000's picture

Agreed, in theory it would work better than nasally, but I’m going for easy admin. Doubt I’ll be able to “back-load” a boof after hip surgery lol

ChemDawg2000's picture

Thanks for the link, but why not share that to begin with? What’s with the attitude man?

ChemDawg2000's picture

You right, you right... Looks like the prednisone my doc gave me might be fuckin w/ my hormones more than I thought. Looks like it’s time to up the aromatase inhibitors hahaha