Liquid Steel's picture
Liquid Steel
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Anti inflamotories, screw the spelling

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Has any ever heard that anti-inflamotories can cause loss of muscle growth?

oversteerisbest's picture

Sorry to bump a dead thread, but I found this by searching, and so others probably will too. NSAIDS can inhibit protein synthesis in high enough doses, which will inhibit your muscle growth. However, training through an injury without taking the steps to fix it (not surpress the pain and keep training dummies) will cut your cycle short which WILL inhibit muscle growth. Whats the rest of your cycle worth to you?

LOKI 1's picture

I believe i read this awhile back stating nsaids inhibit muscle growth with short term use. Then another group did a study with long term use of nsaids and the group actually gained more muscle than the group that didnt use nsaids. So the consensus was if you use em stay on them. Their was alot to be debated tho. Age of groups was one compared to the study you referenced.

jprizzle's picture

I have read this somewhere awhile ago. The article said they do inhibit muscle growth. Don't remember the page

10000ngdl's picture

NSAIDS kill more than 16,000 people in the US alone each year.
You take a whole bottle of asprin and you are dead, take a whole bottle of dbol and you get a stomach ach

homebrewed's picture

I have heard about Nsaids hurting muscle growth. I take them by the handful and have never had a problem building muscle. I call bro-science on that one. Oh and kimmi11...AIDS (ass injected death serum) will for sure hinder muscle growth. Thought you should now. ;} I kid.. EDIT: I JUST REALIZED I BROUGHT ONE BACK FROM THE GRAVE. Sorry guys.

homebrewed's picture

Now that I have had a minute to re-think it..Maybe it differs from person to person?? Who knows.

kodiakGRRL's picture

lol and I tell you the same thing I said many weeks ago.. anti-inlfamitories interfere with muscle regeneration and recovery. you shouldn't take them if you don't really need them AND they can cause bleeding in your stomach which leads to blood loss and very serious health risks like heart attacks and death ..

Liquid Steel's picture

Do u think that Vicodin if used for all the wrong reasons could cause someone to age quicker than normal? I swear I have a friend who pops these like tic tacs and she's lookin older and older! She jus may need to find the fountain of youth b4 30 if she don't chill on these pills!

kodiakGRRL's picture

EVERY time you place a "medication" in your body, you are injesting poison. there is no way around it and if you have a good internist he/she would confirm it. NOTHING in excess is good for you. (even sex) lmao..

kimmi11's picture

Are there any people that are against same sex marriage that aren't religious? I doubt it. Knight Ender Edited to delete unnecessary inflamotory paragraph.same minority that the holders of 'traditional values' usually try to screw over.
screws

homebrewed's picture

O_o WTF?

Liquid Steel's picture

X2 WTF lol

10000ngdl's picture

there is a link in that post probably spam.
Bad ass bike by the way I have an K7 gixxer 1000
wanna race?

Liquid Steel's picture

Man post some pics bro! I luv sport bikes! Ya lets run emm! Thats 1 bike I have never ridden is. Gixxxer 1000' how u like it? I had a 1997 gixxer 750 was a sweet bike!

dudsy's picture

Bloody hope not, I take a fair few celebrex.

DBG's picture

Never heard this...although I did read some stuff before about OTC pain killer/NSAIDS having funny reactions with orals. As far as my joints hurting on cycle, I just deal with it.

Bitch-Tit's picture

check this out:
Why Pain Killers Can Stop Muscle Growth Dead in Its Tracks
Marc Jennings

Posted on 05.2.11 Body Basics 0 Comments

Editor’s Note: Are you suffering from pain and soreness after your workouts and popping pain killers for relief? You might want to think twice about using pain killers after reading this article!

Over-the-counter pain killers (such as ibuprofen) are a popular way to ease the pain and soreness that manifests itself 24-48 hours after a tough workout. However, what most people don’t realize is that high doses of these pain killers can “blunt” the normal rise in protein synthesis that occurs after exercise. In other words, while they can control the pain, regular use of these pain killers could put the brakes on muscle growth. Pain killers Protein synthesis is one important factor controlling the rate of muscle growth. In simple terms, your muscles grow larger when protein synthesis is greater than protein breakdown. Think of your muscles like a bath. Water coming into the bath is known as protein synthesis. Water leaving the bath is known as protein breakdown. When there’s more water coming into the bath than there is going out, you’ll end up with bigger muscles. One of the ways that pain killers such as ibuprofen work is to suppress the synthesis of substances known as prostaglandins. However, these very same prostaglandins also have a profound effect on muscle growth. Some evidence linking prostaglandins to a reduced rate of protein synthesis comes from a trial published in the Journal of Clinical Endocrinology and Metabolism. A group of male subjects with an average age of 25 were assigned to one of three groups. All groups performed 10-14 sets of 10 eccentric repetitions for the muscles on the front of the thigh.

After completing the workout, group one received the maximal over-the-counter dose of ibuprofen (1200 milligrams daily).
Group two was given acetaminophen (4000 milligrams daily).
The third group received a placebo (a “dummy” supplement) that contained no active ingredients.

When muscle samples were analyzed 24 hours after exercise, levels of a prostaglandin called PGF2 increased by an average of 77% in the group using the placebo. This represents the normal response to exercise. However, PGF2 levels dropped by 1% and 14% in the ibuprofen and acetaminophen groups respectively. Of course, this was only a short-term study. The extent to which the prolonged use of pain killers affects muscle growth over a period of several weeks or months is open to debate. However, while the occasional use of pain killers isn’t likely to cause a problem, they’re certainly not something you should use too often. If you do want to avoid feeling sore after exercise, the best way is simply to ease your way into a new training program gradually.

Read other articles by Christian Finn

original link is here: http://mens-total-fitness.com/pain-killers.html

kevin777's picture

I have read that nsaids can inhibit muscle growth.

Beachbdygrl's picture

I've never heard that. They aren't great for your stomach, but that's the only thing I've heard. This is interesting. Where did you hear this? I really want to look into it.

Liquid Steel's picture

A guy at the gym told me that, i have never heard that!

Liquid Steel's picture

I was thinkin thats why i didnt place in the EBC!! Lmao ok maybe not!