posted Fri, 09/25/2026 - 14:35
316
Ozempic etc causing blindness
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We are here to keep each other safe but this is open to real world scrutiny. We're as the glp 1s are causing gastro pareisisis....paralysis is the stomach permanently....the claims of blindness are piling up.
Discuss....?
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RestDayHeroI think both are worth talking about but “permanent stomach paralysis” is probably getting ahead of the evidence. GLP1s definitely slow gastric emptying and there are real gastroparesis cases but that doesnt mean everyone who gets it is permanently damaged.
The eye stuff is more interesting imo. There are now several studies showing a possible NAION signal with semaglutide, although the absolute numbers are still pretty low and not every study agrees.
So yeah I wouldnt dismiss either issue but I also wouldnt turn reported cases into “GLP1s cause permanent paralysis and blindness” yet. We need better long term data.
The data these claims are based on is garbage. Diabetes, high blood pressure, sleep apnea, and age are all major risk factors for this type of vision loss. People prescribed semaglutide tend to have more of these problems to begin with. GLPs are miracle drugs for obese people and people who generally struggle to lose body fat. The net positives outweigh any potential negatives and it isn’t close.
It will be interesting considering all the hidden proofs coming out on mrna. Anything with massive monetary gain brings speculation.
As someone who's on a low dose reta I'd like to request an eroids update to put the forums in braille please.
That would surely suck. Build up muscle to have chick's stare but ya can't see them. Lol!
I guess you won't see your own gut either haha
Hahahahaha!!!! Great thinking!!!
Novo Nordisk and Eli Lilly have put out these statements. “58 Million patient years” LMFAO
The respective positions and rebuttals put forth by these big pharma companies include:
Novo Nordisk (Ozempic & Wegovy)Rebuttal Statement: Novo Nordisk has explicitly stated that the personal injury lawsuits filed against them are "without merit" and that they are "vigorously defending" themselves against the claims.Data Defense: A spokesperson for Novo Nordisk highlighted that semaglutide has a "well-established safety profile, supported by robust clinical development programs, with exposure from post-marketing use of over 58 million patient-years".Lack of Causality: The company points to a large, company-funded study analyzing randomized controlled trials of their GLP-1 medications, which found no increased risk of patients developing NAION. Their medical teams have maintained that data from internal assessments does not suggest a causal relationship.Eli Lilly (Mounjaro, Zepbound, & Trulicity)Rebuttal Statement: Eli Lilly has taken a more reserved but protective stance, stating that "patient safety" is its "top priority". While they have declined to comment extensively on active litigation, they state they will "continue to review data, including any data regarding ophthalmic issues."Legal and Clinical Argument: In court filings, Eli Lilly has asserted that current medical studies do not prove GLP-1 medications cause the condition. They maintain that their drugs are entirely safe and effective when used as directed.
Yes they're gonna fight for their pile of gold. Im wondering how long til courts evidence comes. Will be interesting!
This happens often with new drugs. Nobody knows the long term effects until long term comes. This is the reason I never jumped on the GLP train. There is still very little data.
That said, Im curious if other health markers may push certain populations to this issue. Like how many of these blindness case are among a healthy(ish) gym going group, vs fat lazy fucks that havent changed anything about their lifestyle apart from the GLP.
EDIT: I just want to add something. I know many people in this community use GLP drugs. But are they really that necessary? Dudes have been getting jacked and shredded for decades without them. Yall dont need that shit. I know its a bit hypocritical considering all the other stuff I (we) are using, and probably a very unpopular opinion, but I had to say it. And I respect if you disagree, but I havent and will never touch them.
Im with you, I wanna see more research before I start pinning that stuff. Ill stick with the basics.
The shit work amazingly tho... its crazy how ripped people are today vs 10/20/30 yesrs ago.
There's actually already a 20 year history of safety data for the class. Semaglutide was approved in 2017, but the first GLP1 was approved in 2005. As with any drug, some people will get very severe reactions. Statistically though GLP1's are some of the most well tolerated drugs in all of modern medicine.
We also watch how safe mrna was...right?! Until it hit court in europe and pfizer people admitted on purpose..... covid goes back to 1965.
Im curious where it goes.
Gastropariesis is no joke. Blindness...ouch
https://pmc.ncbi.nlm.nih.gov/articles/PMC11790292/
https://www.drugs.com/medical-answers/what-long-term-side-effects-ozempi...
Agree! Per research it appears as if its aimed towards diabetics. But considering the modern fda and newer to market. On point!
We are gonna have to wait and see how the evidence shows, and what Big Pharma's defense against the claims is, but im personally already decided.