+ 3 A Little Abstract for EQ Lovers
https://www.ncbi.nlm.nih.gov/pubmed/29148625
The link provided only contains an abstract of the full study; nevertheless, its conclusion is that Boldenone might be more deleterious to the kidneys than a variety of other commonly used AAS, three of which were measured and compared in human participants: testosterone, nandrolone decanoate, and methandrostenolone. Although I am no scientist, I think further studies are needed before arriving to the same conclusion as the researchers who published this study. It is known, for example, that elevated creatinine levels render a false positive on kidney function tests; perhaps this study's results are indicative of just that, and I found another peer-reviewed article corroborating that hypothesis (see https://academic.oup.com/ndt/article/26/2/744/1895343). Still, it doesn't quite explain increased thickness of renal parenchyma, nor the increase in renal volume, as remarked by Kantarci, Punduk, Senarslan, & Dirik.
Can anyone else chime in? I'd love to get to the bottom of this.
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Dehydration can also lead to false positives on creatinine levels which is why patients who take fasted blood tests show high levels.
Great point!
RustyhookerTheres multiple causes. High protein diets skew readings.
https://www.mayoclinic.org/tests-procedures/creatinine-test/about/pac-20...
Great information!
Truth is it’s not a surprise.EQ is known to raise RBC,hemocrit,and blood pressure to an extent as well as fibrinogen.These increases put pressure on the kidneys and the left ventricle of the heart.This is why bleeding is so important,especially on EQ.
Unfortunately, this is an example of why you should never simply surf abstracts. The methods are unclear as to whether group 2 gives individual compounds usage across the cohort, or the combo of 3 in every individual as a cycle. With a combination, it is impossible to conclude what caused certain issues. It is also impossible to understand whether compounds were used individually, heightening a lack of clarity on whether any specific conclusion can be drawn about EQ. Furthermore, we have no details of the diet invoked across the 3 groups and perhaps critically; this could indicate a lack of controls where a 4th control group could have been nosteroids+normal protein, versus; nosteroids+high protein.
I tried to get a hold of the full article across the sources I have, but can't. I have requested it from the authors, but it'd be unusual to get it that way.
It looks like a really interesting study.If I get a hold of it I will let you know. +'s for thoughts.
Unfortunately, I was also unable to access the full article. I typically don't cite mere abstracts, but given that research is so limited on the topic of AAS use by bodybuilders, I couldn't pass it up. I have asked many of the questions you have, and I am itching to get my hands on the full study to see what types of controls were implemented, if any, to gain a more comprehensive understanding of all the variables involved that contributed to the different outcome for group 2.
As an aside, the second (full-text) article I cited explains the elevation in kidney values; still, it doesn't quite satiate my intrigue about the first article I posted.
I'd be interested to see that..
You're not the only one! I hope someone is able to share the full article with the Eroids community.
My egfr readings always come back bad but I've had the actual urine test and everything was gtg. The important thing to remember is the e stands for estimated. The 24 hour urine test is the only correlation t way to measure that. +2