posted Tue, 10/11/2016 - 01:05
2987
+ 1 help: low igf-1 on 10iu hgh per day
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I want to know if there is some explanation to my low level of igf-1.
Iam on hgh at 10ui per day, split morning and after train, for more than 5 months.
My serum level is around 35, that it is ok, but my igf-1 is around 230.
I do not take any antiestrogens or AI.
My liver values are normal.
what can i do? Can be this normal???
Thanks! !!!
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Very strange. I also agree the best course of action would be to take some time off then re-start at a lower dose and test IGF again. Good luck brother and keep us updated.
FR sent
I use somastin.
strong side effects.
No fat loss because i use slin too .
lot of pain in wrist. Tingling in fingers.
I need sleep a lot.
I know is legit. Second bloodwork i did with 15iu was more than 70 in serum.
But igf is low...
Have you used other HGH brands? If so, can you give us some info on the IGF1 results with those? That would help (comparison)
No. Sorry ...
I did 3 times with this brand.
the first was 310 with 10ui
The second was about 230 with 15iu. ...
310 seems low for 10ius
When HGH is prescribed for Growth Hormone Deficiency (Adult/Adolescent) IGF1 is monitored for protein immunogenicity or tolerance (low to no change in IGF1)
Such a high dose for 5+ months....sometimes more doesn't mean better
As long as you are a healthy individual (no liver issues) you might try to come off completely for 1-2 weeks then "restart" with a normal dose (3-5ius SubQ a.m.)
Do another IGF1 and see where you stand
The GH is legit (elevated GH Serum)
Maybe Karl can chime in with some info also
Karl is intrigued himself ;)
As the customer reported, and as all GH serum tests show the GH is working, and working properly, the IGF1 serum results really depends as we all know on multiple factors, and in general are very individual, just as you said boss.
What may have explained this is that the customer is using Somedin (IGF1)
Now the member have inquired as well as I and he saw a reference which may explain this phenomenon -
Searching info about igf'1and gh i found this.
Copy and paste :
Studies show that the use of igf-1 lr3 in combination with exogenous GH actually reduces the total area under the curve in regards to the amount of IGF-1 produced. In other words, lr3 will decrease the amount of igf-1 produced by GH administration.
We are actually conducting some similar experiement on professionalmuscle.com on the GH testing thread, I actually mentioned your work there
I'll keep u guys posted
Definitely keep me updated Karl
I've got that new round of SOMEDIN Lr3 (which I really like)
I'd really like to here about 'real world' results - blood work, etc (GH + IGF1 lR3)
Thank You
(He also mentioned using Slin. I have no experience with it.....but just another added element to his protocol)
I will Stop for 2 weeks.
And why subq?
I always take my gh IM.
I think it is absorbed better than subq.
thanks! !
You might want to rethink Sq vs IM - this study is about kids - sure, but I believe the results are still applicable to your/our use of HGH.
https://www.ncbi.nlm.nih.gov/pubmed/3197659
Did it mean that is better SC than IM???
More growth promoting effect, says the article with SC?
Iam confused now...
Actually the abstract states that there was little difference in IGF-1 blood plasma levels between IM and SC...but the researchers found that every day injections were far more effective than other regimens.So I guess that it might not really answer your question. I did read some research that discussed long term effects of IM and SC (again on children) that concluded that SC injections had better long term growth effects. I did a quick search but couldn't find it - however, I am sure that if you are interested, a few Google searches will locate the article.
I opened a post asking for this question : im vs SC?
"IM has a higher absorption rate, 70%, as opposed to 50% with sub Q. IM has a faster clearance rate.
But, subQ has longer igf1 elevation, upto 24 hours."
I will try sc and split in more times.
I stopped more than 15days and will start soon.
I will post blood work.
"split in more times"
What do you mean by that?
Also, you are better off trying a different brand (PHARMA) and then pulling an IGF1
The problem could be you and not the product itself (I've seem this quite a few times)
If legit PHARMA doesn't elevate your IGF1 then you'll know (you keep pulling IGF1 on the same product with the same result.....wasting your time and $)
Injecting IM or SQ is not going to help elevate your IGF1
(Doc recommends SubQ)
For example if I take 10iu per day split in 4times along the day.
Sorry for my english.
yes, i know my hgh works. The problem is mine.
the conversión of hgh to igf-1
there are people with 3ui have 500 of igf and another with 10 no more than 400.
I stopped 2 weeks and will start now and see levels.
Ok
I understand now
doing the multiple split dose protocol (more than 2) usually didn't elevate IGF1 levels better than one early a.m. dose. (Multiple dosing would be more like a replacement dose Vs supplement dosing)
Hope the next results are better.......but....I don't see it changing from your previous results unfortunately :(
saffiredid you solve why you got that low igf?
No still. ..
I had stopped for 15days, and now i going to start another time and see results
That sounds weird to me. My numbers are better than that and I run 2iu morning and 2iu at night
that is really weird dude. What do you feel?? Have you lost fat? Which brand are you using if you can mention it?
Somastin .
I know that it is good because the hgh serum is high, but my igf-1 results are extrange.
No medication, no AI or antiestrogens...
No fat loss but lot of sides