17aa messing with binding proteins of CBG.. well it could get complicated from that aspect but from observation dbol makes people hungry some dont, eq does that too,,,but var is proven shown to interact with GR (cortisol receptor) so it will block it like SERM blocks E at ER. plus faster uptake of T3 makes VAR such a wonderful 'cutting' drug (lowered cort, faster metablism, and anabolic). but if youve taken cortisol before for allergy or have seen people takeing high dose cortisol for rash wahtever, they are ALWAYS hungry, cortisol regulates blood glucose, so those people have too much cort have reduced their insulin sensitivty and hyperglycemic and yet still hungry cuz they are so f'd up,,,so they get fat bloated and ravenous.....so IF VAR does opposite of that, then makes sense people lose appetite,,,possibly might run into cortisol deficiency too (sleepy etc)

tren does something whaky to your thyroid and adrenals too and sounds liek deca increases cortisol (joint improvement)...im thinking about doing blood work later in the future just to prove it...later in the future LOL