+ 5 AAS and Blood Pressure
After a few conversations about cycles and how various compounds can affect BP, I wanted to wrap my mind completely around the topic. Because AAS is such a controlled group of substances, scientific studies are not readily available to us. I spent a lil time digging in the textbooks and online and I was able to compile a few facts to explain the physiological effects of AAS in regards to blood pressure.
Some medical texts suggest that the blood pressure response to AAS is due to sodium-retention properties. The high doses of AAS will inhibit a particular enzyme (hydroxylase), which in turn leads to increased levels of a corticosteroid that inevitably causes sodium and water retention. Further adding to this is the fact that sodium is hydrophilic – meaning it loves water. When sodium moves in the body, water follows. Because the excessive sodium subsequently adds more water to the blood, the volume of liquids and solutes in the blood stream consequently yields increased pressure. Kind of like opening the faucet valve wide open on a garden hose – the more water entering that hose, the greater the pressure.
A newer study suggests another reason for elevated BP. In this study researchers studied the effects of AAS on the release of sympathetic hormones such as epinephrine and norepinephrine. These hormones cause contractions of the smooth muscles of the blood vessels, and chronically elevated levels can cause elevated BP due to tightened blood vessels.
The final factor worth considering is that of cholesterol. It is a fact that some compounds cause increases in LDL levels (bad cholesterol) and decreases in HDL levels (good cholesterol). LDLs have been directly linked to hypertension, whereas HDLs have been proven to lower BP and reduces the risks. Persons with higher body fat percentages are at an even greater risk.
So, now the question may arise as to how to counter these effects. Some may say that a diuretic will keep the water off, so just add that to the cycle. Thing about diuretics is that they cause the body to excrete not only fluids but other minerals and electrolytes as well. This leads to imbalances and a host of adverse effects. Maintaining a fluid balance is the best defense against these adverse effects. Do not use diuretics unless you know what you’re doing.
As for the sympathetic hormones activities, nitric oxide supplements can aide in counteracting them, but only to a short-lived extent. Once again, balance is key – good diet, proper exercise, flexibility, and appropriate recovery. Resistance, aerobic, and flexibility exercises will all increase blood flow to the muscles, which will help counteract the sympathetic hormones’ activity.
Cholesterol… Higher body fat will increase the levels of LDL on its own. Focusing on lowering that body fat to a safe range prior to the use of AAS will be extremely beneficial. Outside of this, certain aspects of the diet can affect cholesterol levels in a positive way. Fiber has been shown to lower LDLs and increase HDLs. Likewise, regular exercise has been shown to increase HDL levels. Once again, balance is key.
References:
http://www.ironmanmagazine.com/steroids-and-blood-pressure/
http://en.wikipedia.org/wiki/Anabolic_steroid
Understanding Nutrition, 10th Edition by Ellie Whitney / Sharon Rady Rolfes
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Good read brother! Something that a lot overlook is the connection between "roid rage" or just irritability/aggression and high blood pressure. I firmly believe that roid rage is a myth. There are definitely some compounds that will assist with increased,CONTROLLED aggression (for training) but uncontrollable rage or aggression I believe is a direct result of high BP. This was suggested to me about a year ago and I tested this theory. Sure enough, when I would feel easily irritated and frankly "Pissed off", I checked my bp and what'd ya know! Yup, high blood pressure. Good post bro! +1
AnonThank you sir. I agree with you 100% on this point. I think a lot of this cause/effect is due to the sympathetic hormones I mentioned above. Epinephrine, which is adrenaline, is the fight or flight hormone. A cascade of reactions take place when it is secreted, to include elevated HR. very good points.
Give them a vote if you find it helpful.PermalinkAnonyou don't think it could be an opposite cause and effect... you get high BP because you are raging, compared to the likewise?
You're using the word "raging" like its a given. I strongly disagree. I am perfectly fine 90% of the time. When I do start feeling "irritable" (which leads to the raging) I notice my bp is high. Example, at work. Day is going fine. Happy , smiling. Then I start feeling a little edgy. Crabby. Then someone pisses me off. I wasn't raging. I was fine. I grew irritable. It's always my bp
My point is I never just rage. Well I can't say never buy when I do it's just my short fuse. Few and far between now in my old age. But I do get irritable. Sometimes my AI needs tweaking. Sometimes it's just the nature of the beast. High bp is a common side and I believe it is what causes these so called fits of roid rage
Anonyea I totally agree, lets take gear out of the mix all together... lets say you get in a car accident and its the other guy's fault. I know I am going to "rage" (or whatever you want to call it) and I have a good hunch you are too. My BP is going to skyrocket because Im pissed at this dude, gear or not. But just to clarify, I think AAS just magnifies whatever emotional feeling one has presently, if one is happy he/she is super happy and if one is anger, he/she is super angry.
Ok, I'll give you that. AAS amplifies emotion ,good or bad. But when you're not quite feeling yourself. Maybe you were perfectly ok and suddenly notice you feel irritable or on edge. Check your bp. I'm challenging everyone to do so. I'm not just pulling this out of my ass. I raised this question about a year or so ago and I was challenged in this way by the one and only Guru. Sure enough, my bp was high. So was my estrogen I found out later.
Anonnice info, I use the car accident scenario because it happened to me on the 26th of this month, I almost freaked on the dude, but told him to leave me alone for 15 min then we can exchange information. I gathered my thoughts and calmed down, and did the "insurance info exchange" without any outbursts or anger... with a quick change of subject, are you really 7ft tall 400lbs?
I don't want you to think I'm disagreeing your point. I agree that rage or anger will raise bp. That's a given. I just think its two separate issues. Getting in an accident is going to enrage most of us. But gradually getting irritable is something different and that is what I believe "roid rage" is blamed on. That short fuse, irritable, moody episode. My wife used to say "you're mean on cycle". That's what I'm saying. Bp is elevated, you'll be mistaken for a roid raging asshole.
Anonyeah I wasn't disagreeing with you on high BP causeing anger, just picking your brain on some diff scenarios
Good read bro +1...any take on donating blood while on cycle?
Anondumb question: would giving blood with aas, and possible elevated estrogen and test be good for the patient receiving it??
I'm on TRT and give blood. Red Cross ask what I take and I tell them Test Cyp and they have no problem with it. The lady even commented that it was good to have the extra red blood cells. I'm just glad they don't ask how much I take....LOL
Thanks buddy for the straight 411
Don't hold me to this...but I thought TRT users are expected to donate blood because of the high red blood count. Whoever gets the blood, testosterone is taken care of by the kidneys and liver or used by the body. I assume the same would also happen with estrogen. Maybe someone can chime in to confirm or correct.
AnonMakes sense, if the body can filter checmicals such as meth, it should be able to filter natural occurring compounds.
Who knows? Maybe women would get a short term libido increase too because of increased test.
Anonthat's a really good question. i've heard of donating blood to lower enzyme or estrogen levels quickly. it would seem reasonable to assume that your test serum levels would drop respectively also. so, maybe i'll post a thread to see what the more knowledgable have to say about this, because you sparked my curiousity. i have given blood on cycle before. labs were not part of my regimen at that time, tho. have you ever given blood before?
Not on cycle, I do regular cardio anyway and it seems to help keep BP under control...but was curious if this would be another means to combatting high BP on cycle. It would be interesting to get a take from others.
Anonlogically, the benefits, if any, would only be short lived. although BP is affected by many variables, it ultimately boils down to the volume of blood and blood solute levels. removing a pint of this volume will lower blood pressure UNTIL red blood cells have been regenerated.
Anondoes donating "plasma" have the same effect as you stated earlier?
It'd be stop gap unless you this could be done with some sort of regularity, say once a month, just throwing out a number.
AnonAnd a lot of times if you have been overseas in the past year or so, blood donation companies will not allow for donation either.
AnonLife share won't let you donate for at lease 2 months at a time. Gotta let the body rejuvenate and stabilize
i went to use the arm cuff BP machine at walmart, first it numbed my arm then I flexed and I broke the cuff, then straight total recalled that bitch and escaped like arnold.
Anonyou need to get back on your game, brother! we need some basic, yet healthy recipes for our fat asses!
Anonlol! i have the same problem. never measured my armsm but my triceps are pretty big. my ole lady takes my BP at home with the old fashion cuff and stethescope. she has trouble getting that thing on, but we manage. i tried using the one at the grocery store the other day. couldn't even get half way up my bicep. guess that's not entirely bad.. lol
Nice read brotha good shit as always! X) +1
Anonthanks homie
Give them a vote if you find it helpful.PermalinkI could have missed it in here, but I keep hearing that lowering sodium intake on cycle will also help keep blood pressure in check.
Hey Dossy,
Don't ya love paradox?
I shoulda known - been feeling the increase in pressure. Because I felt it, I checked it yesterday and not too bad 136/86 - heart rate was elevated at around 88 BPM - but I wished it were a bit lower on all sides - and typically is lower (more like 120/80 and 70 BPM). But, I've had to work to get it in the normal range. I've been riding the lifecycle bike 5 days a week/30 minutes at 140 beats per minute for 30 minutes for about 7 years. I'm gonna start checking the blood pressure at least 1/week to see where this goes, but it looks like I'm gonna have to go to 6 or 7 days a week on the bike - and/or longer than 30 minutes each trip if I want to incorporate the AAS. And I know I have to do this quick - because blood pressure goes up 7 times faster than it goes down. Getting old is a work out all by itself! I definitely noticed after starting AAS big time on the bike that the heart rate jumps way up. For example - I usually ride at level 7 to get 140 Beats per minute. Since my first Test shot last week - I'm down between levels 4/5 on the bike to get to 140 BPM. Which is way less effort (level 4 vs 7)- but produces the same heart rate. I obviously don't live to ride a life cycle - I ride to live.
Which reminds me - He died so I can live and I live because He died. T Sound familiar?
AnonGOOD STUFF
Anonhomeboy! how's it hangin??
Very good read bro! +1 from me.
AnonThank you sir!
Give them a vote if you find it helpful.PermalinkAnonGood stuff as.always..+1
AnonThanks bro. I try
Give them a vote if you find it helpful.PermalinkGood read. I'm giving you a +1.
Welcome to level 2!
AnonThank you brother! I spent my entire morning jotting these notes. Glad to be able to post it.
Give them a vote if you find it helpful.PermalinkAnonhaha... i just realized that my notes for this thread are in the background of my shops-mart reship pic i posted yesterday.
With all that said (great read BTW), I wonder if adding GW501516 to every cycle would help.......
GW-50156 regulates fat burning through a number of widespread mechanisms;[8] it increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization.[9][10][11] This shift changes the body's metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar.[12] GW-501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW-501516 may have a protective effect against obesity...
It has been demonstrated at oral doses of 10 mg a day to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation.[14] Treatments with GW-501516 have been shown to increase HDL cholesterol by up to 79% in rhesus monkeys and the compound is now undergoing Phase II trials to improve HDL cholesterol in humans.[15]
AnonI am not very well versed in peptides.. It seems there are a lot of benefits with this particular one, though. The key point I can see here in regards to blood pressure is the effects it has on cholesterol. Increasing HDL levels will subsequently decrease circulating LDLs. This is the homestatic response that our bodies are programmed for. The reductions of body fat will help, but the fact that body fat may still be high proves that the contributions in this aspect will be more of a longterm benefit, since the currently high BF will still contribute to elevated BP.
Maybe some of the vets can shed some light on the peptides roles here.
Good post, btw. Thanks for adding this.
Give them a vote if you find it helpful.PermalinkI have been researching the GW for only about a week now. when I'm on a cycle I have borderline HBP, so your post was really interesting to me. I think I am going to take the plunge and order some (even though it is higher than giraffe pussy). I hope some of the vets would comment about running this with tren ace.
AnonI'd say post a thread about your questions. I hope your age and cycle experience is up to par, otherwise you may not like the responses. Lol. Seems the word tren attracts confrontational conversations.
yeah bro, 39 and about 12 cycles under my belt. Been off for a cpl years though and I am preparing to get blasted for my BF% and considering even using tren right now.lol
AnonGotcha. Post a thread bro. Can't say shit about cycle experience. Hell, I'd even leave it out for a minute just to see how many assholes try to flame you without knowing the facts. Lol. Have you ran tren or deca before?
deca yes, tren no..... Been feared of it. Ordered some TMT but like I said BF% is in high teens and I think tren sides are associated with BF. IMO Thanks for accepting the FR will stay in touch on PM so not to highjack your post anymore! lol
AnonNo problem bro. I post to help people, not get attention. You can post anything you wish in my threads.
AnonI feel the same way...just the names of each peptide alone is confusing, along with GH.. Ill be studying up on both in the up coming months
Anoni have a few things in my forums about gh benefits.
http://www.eroids.com/forum/hgh-peptides/rhgh/gh-short-term-effects
http://www.eroids.com/forum/steroids-qa/pct-anti-estrogens/hgh-during-pc...
The second link is a study I found regarding anabolic effects of gh during induced hypogonadism. In that short thread, there's also a link to a thread by Tread. All good reads.