posted Sun, 02/09/2025 - 10:34
1056
When to drop AI after adding Primo?
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I'm currently running 500 mg of test. I take aromasin as an AI. I want to add in some Primo, but I know it can act as an AI. I plan to start the Primo around 1:1 ratio with the test. Should I wait a week before trying to drop the AI? Should I drop the AI as soon as I start the Primo? I understand I'll need bloodwoork eventually to get it dialed in, but just wondering about the timing of when I should drop the AI... Thanks in advance.
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Ummm....blood test says so....????
When I run test primo at 1:1 I need 0.5mg Anastrozole eod to keep my levels right but I run 700/700mg
What the gentleman said below ! Blood work ! And track of how you feel daily !!
I do keep a detailed log - thank you.
Primo, at 1:1 barely did anything to my estrogen levels, some people don't respond in that way.
Equipoise, at higher than my test did the trick, got my e2 down and let me drop the AI's.
Not suggesting Equipoise, just saying you can't bet on primo suppressing your estrogen, straight up didn't work for me. I doubt it was fake primo, because I bought from 3 seperate sources to try and eliminate that possibility.
Thanks. I did read that Primo does not have an anti-estrogen effect on some people. I guess I'll find out soon enough!
Just drop the AI you'll be fine. By the time it's worked it's way out of your system completely the primo will be coming online. No need to over think it.
Thanks. It's easier for me to deal with high E2 than crashed E2 so this path seems to make sense for me personally.
Bloodwork bloodwork bloodwork
anvilNo ratios, no stopping AI, its not a guessing game. Just get the blood work completed and you will know.
Agree on the bloodwork, but you need a starting point to use for a while before you get the bloodwork. Just looking for the most sensible place to start.
anvilThere are no none ratios, I can go 1:1 my estro doesn't change. You can do the same and estro can drop to 9. The only way you can tell is blood work, can see by the replies you got some had it drop it and most had no change. It is totally person dependent, that is why the only answer is blood work because the chance it does nothing is there and you are taking an AI for a reason correct?
Yes, I'm taking AI for a reason and I appreciate your perspective. However, I'd rather have high E2 than crashed E2 because I can feel high E2 coming. High E2 raises my diastolic blood pressure and gives me a red face as an early symptom. With low E2 I feel fine and then 6 hours later my brain is fogged up and I'm psychotic! For me it's easier to deal with high E2.