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HCG and When to Use It

A lot of cycles recently have HCG in them and I think that we must understand exactly what the purpose of HCG is and how to properly use it on cycle and PCT. HCG is only used on long cycles or extremely high dosed cycles. Not on a Test only cycle lasting 12 weeks or stacking with another low dosed compound. 12 or more weeks and heavy dosages warrant the use of HCG. Let’s look at why….

"Human Chorionic Gonadotropin (HCG) is a hormone produced during pregnancy that is made by the developing placenta after conception, and later by the placental component syncytiotrophoblast. Some cancerous tumors produce this hormone; therefore, elevated levels measured when the patient is not pregnant can lead to a cancer diagnosis. However, it is not known whether this production is a contributing cause or an effect of tumorigenesis. The pituitary analogue of hCG, known as luteinizing hormone (LH), is produced in the pituitary gland of males and females of all ages.

HCG is clinically used to induce ovulation and treat ovarian disorders in women, as well stimulate the testes hypogonadal (underproduction of testosterone) men. It is also used in the treatment of undescended testicles in young males called hypogonadism. HCG in males is similar to LH, because they are similar and LH binds to receptors on Leydig cells stimulating synthesis and secretion of testosterone, the use of HCG is an added bonus to steroid users even if there is a lack of endogenous LH. Since HCG increases the body’s natural testosterone levels, its use during long or extremely high dosed cycles can be most beneficial were the effects on the hypothalamus causes a depressed signal to the testicles. The result of the depressed signal leads to what is known as testicular atrophy (shrunken nuts). The use of HCG will send an artificial signal to the testes (again, as if it were actually LH), thus preventing (to some degree) atrophy. It not only helps to maintain testicular size and condition but it will also help in restoring testicles back to their original size. Restarting natural testosterone production as quickly as possible is extremely important in regulating our hormones back to its normal balanced level."

Now how to dose it….

Any more than 500IU of HCG per day cause too much estrogen aromatase activity. There is a theoretical belief that aromatase is actually toxic the Leydig cells of testes. Understand you are inducing primary hypogonadism (permanent) and treating steroid-induced secondary (hypogonadotrophic) hypogonadism (temporary).

250IU or 500IU on two days each week while on cycle is the usual dose to combat testicular atrophy, if it isn’t enough then use it more days each week at the same dosage rather than raising it because of the aromatase activity involved with doses over 500IU. Usually you start the HCG 2 weeks after you start your cycle and you can start it at the mid-point of your cycle until you finish. I always say let your body be the judge. You know your jewels better than anyone. If there is significant shrinkage compared to your usual, then its obvious.

At the end of the cycle after one week you can stop and the next week start you PCT

If you decide to use HCG in your PCT it is the same dosage of 250IU or 500IU for 10 – 14 days and stop. The testosterone production it induces will cause issues with recovery because it will continue to suppress the Hypothalamic Pituitary Testicular Axis (HPTA). This is where the standard PCT picks up and finishes the job making your cycle successful and complete.

Dosages for mixing:

Bacteriostatic Water for dilution is used.
5000IU/10ML mixed HCG is dosed as so below. Same thing if it’s a 10000IU/20ml mixed vial
250IU is 0.5cc in the syringe (50 units in a insulin syringe)
500IU is 1cc in the syringe (100units in a insulin syringe)