600 mg/wk 01 Nandrolone
I
Next we look at a study conducted with HIV+ men, whicl charted the lean-mass-building effects of nandroloni decanoate324• 30 people participated in this investigatio~ with each given the same (high) weekly dose of this dru~ Half underwent resistance training so that two group (trained and untrained) were formed.The dosing schedull was quite formidable, beginning with 200 mg on the fir~ week, 400 mg on the second, and 600 mg for th! remaining 10 weeks of peak therapy. Doses were slowl] reduced from weeks 13 to 16 to withdraw patients slowlj from the drug. Potential negative metabolic changes werl looked at closely, including cholesterol and lipid level' (including subfractions of HOL and LOL), triglyceride~ insulin sensitivity, and fasting glucose levels. Even with th1' high dosages used here, no negative changes were note~

in total or LOL cholesterol, triglycerides, or insuli~ sensitivity. In fact, the group also undergoing resistance exercise noticed significant improvements in LDL particle size distribution, lipoprotein(a) levels, and triglyceride values, which all indicate improved cardiovascular disease risk. Carbohydrate metabolism was also significantly improved in this group. The only negative impact noted. during this study was a reduction in HDL (good) cholesterol values similar to that noted with the testosterone study, with an 8-10 point reduction noted between both groups.