posted Thu, 09/10/2026 - 00:44
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+ 2 Nandrolone mental side effects
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I’ve been running 500 test E , 250 mast E and 250 NPP for just around a month now , had no side effect issues when running just test and mast but since introducing NPP I’ve encountered a few mental sides and will probably drop NPP because it’s beginning to put a strain on some aspects of my life , I’ve been encountering mild depression symptoms and I’ve become extremely distrusting in the people around me , does anyone else have any experience with this and how did they go about clearing these side effects up or is it just better to get off nandrolone and take some time for it to clear up ( if so how long might this take ?)
Thanks for any help you guys might be able to prove 
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Nandrolone's progestogenic activity spikes prolactin, causing anxiety. Get your prolactin/estradiol checked, taper off the compound, and give your body 2–4 weeks to restore your mental state.
Pipeliner47Anhedonia. Cut it and up your mast as mentioned below. Bet your case will be very mild. I've had it several times. That's why I absolutely run 5-10g glycine during 19nor cycles. Helps balance nt's. One thing I will never Ever touch again is tren E. Once you've had a hard dopamine crash it takes months to get back to yourself. I think after that cycle it took me a year + to feel normal again.
19nors also alter the glucocorticoid receptors, sometimes permanently. Once I found out that they have linked trenbolone to Alzheimer's from basically eating your brain. That's where I drew the line. Anyways here you go: about nandrolone + depression. Pretty common
https://pubmed.ncbi.nlm.nih.gov/24490270/
I've been running 500 Test C, 400 Mast E, 400 NPP with 300mg of P5P recently upped from 200mg cause I was getting some prolactin side and mentally been okay. I 2nd upping the mast and adding in some p5p if you're not already running it
Estrogen high and prolactin follows...get bloods before you chase a guess.
Up the Masteron dose. Boom, nandro sides eliminated.
Pipeliner47^^this
Just effects people differently I guess, I love NPP/Deca and I have never had any negative sides like that, but easy fix is to drop it and see if you’re feeling any difference.
I agree. I think some drugs are just not for some people.
I ran Test C at 500/wk along with Nandrolone Decanoate at 600mg/wk for 16 weeks and had no negative sides. While NPP is supposed to be more manageable because of the faster ester, I wonder if the fast effects is what made the difference for you. We all have different metabolisms and tolerances and have to figure out what works best for us. Tren makes me paranoid that my wife is cheating, but I’m able to compartmentalize that and keep rational since I know it’s just the tren. Not sure how helpful this is for you but I appreciate your post because I’m always learning and I’ve never tried NPP.
This is the exact issue that I’ve had with NPP but in the moment it slips my mind to think I’m being irrational because of the nandrolone , constant cheating paranoia
Tren is great! it gives me good mental effects(at least I think LOL), strong increase in drive and It can give you a short fuse but if you're a calm person you can manage that well. As long as you aren't pushing crazy dosages.
NPP was the complete opposite for me, a week or two after introducing it I had almost zero motivation/drive, slight depression and low libido, strength even went down some initially. I pushed through it a couple more weeks just to see if they subsided but only by a hair. I eventually dropped it and added in some Proviron at 50mg a day 25mg am/25mg afternoon and all those sides went away almost instantly.
Do you already have depression issues or anxiety?
In my experience NPP makes my naturally short fuse much shorter. Its easy to tell yourself that you will just remind yourself that it's "just the steroids", but it's real easy to forget that in the moment. It's the reason I'll probably never try tren unless I'm living in Antarctica.
Mental health is no joke, and if something makes you "potentially" do something you will later regret it becomes irresponsible to continue using it. Just like not getting bloods or running excessive amounts of gear endlessly, there's a component of personal responsibility that goes along with this.
It's good that you're confronting it. Let's all hug now and play soggy waffle.
RIPMIX
"how'd you get in prison?"
"RIPMIX"
+gay raped a British guy in a shoulder sling @press1
TOTALLY WORTH IT!
Yeah I’m exactly the same it’s reassuring to hear people with similar experiences, bring on the waffle
If you have good self awareness you can fight back against the mental sides by identifying your emotional state and circumventing them so you are your normal self.
Npp usually starts to hit me like you said a month after starting then I tell myself quit being a bitch then I am good.
If you look for the sides you will find them… it’s called “Nocebo effect” look it up if you don’t believe me
I’d be tempted to try this approach but it’s honestly putting a great deal of trouble between me and my girlfriend so I’m lowkey just gonna up the test a little and drop the NPP or maybe look into another compound to drive my strength up
I get like that more off of tren … before you quit check your hormone levels sometimes elevated estrogen and prolactin can do that to you . Do you have ancillaries on hand in case ?
Bloodworks all in line which is why is annoying me I didn’t even consider it could be the NPP until a good friend pointed it out to me that it could be lining up with certain stuff I shared with him
Pipeliner47If your getting that from npp I would stay far clear away from tren
I’m taking NPP right now and can also attest to the fact of mental sides. However, and strangely, I’ve taken a different view of these sides. It’s making me be more aware of my emotions, reactions and thoughts. I actually feel like because of this I’m more aware and able to recognize anger, jealousy, sadness, insecurity or resentment and regulate this behavior. I think the introspection is a coping adaptation to the side effect. normally something bothers me at a 3/10, and on NPP it becomes a 7/10. I now recognize that and can tell myself hey, I’m reacting much more strongly than I normally would. I need to understand what I’m feeling before I respond. In the long run I think this sort of thought process will help me deal with emotions even when not on cycle
Fricken BINGO dude. I think you explained that perfectly. I can’t say I’m experiencing any mental sides. I may get a tiny bit more annoyed or flustered, but I very quickly am reminded that I’m on a cycle and need to keep the ‘tude in check. So maybe a very small, mild side effect. I’d like to think I’d keep that mindset if the mental sides do arise/come on strong. So far, 0 issues on 400 Test Cyp, 300 NPP, 300 Mast E and 50mg anadrol PWO, 6 days a week. I feel like an absolute gorilla! I’m in a fantastic mood all day, basically counting down the hours until I can lift again.
Yeah I very much agree with this , as a result of having to adjust I do feel I can handle my emotions in a different way than I’m used to and I do feel it could potentially cause some growth in character but I don’t believe it’s worth it
With NPP it takes about 3 days to clear out of the system mate. All depends on the Lab you use mate - there is only one Labs NPP I can run, all the others make me feel weird and gay.
You just ARE weird and gay.
And?
Out of curiosity what do you mean by weird and gay? I for me I haven’t experienced anything like that
LMFAOOO!!! It doesn't make me feel gay mate - well apart for @Milfpounder
The others do make me feel weird though, not a great feeling. The one I use just makes me feel awesome, great appetite and full of mental clarity. I've used over brands that have even given a green tinge to my vision LOL
Lmao I didn’t think you were being serious but I’ve heard of people having weirder changes on cycle so nothing shocks me these days lol
I think I can guess the brand. rhymes with arm-a-hoe
Or Camel - toe
Amazing there is a difference between labs, great to know. I will give another try
Drop the NPP. Assuming that you’re eating to grow, training hard and getting to bed on time, running 1g of gear should be enough for most of us to make great gains. That goes down the toilet if you’re not mentally well.
Yeah I’m definitely going to , do you know how long it can take the mental sides to clear up , I’ve heard some people say it can take quite a long time
I’ve yet to run Nandrolone so I can’t speak on experience, but I hear this is a common side effect with many even using either short or long ester.
Yeah I honestly was kind of stupid in my approach to it , I thought if it’s a much milder 19-nor than tren it’s gotta have much milder sides if I keep the dose sensible but it seems that a lot of them sides line up with what I hear about people on tren
Are you taking anything to combat the rise in prolactin from the NPP? I am on 150mg a week of Tren Ace right now and have been taking 200mg P5P daily every morning with my shot. I just got my blood results back and my prolactin is sitting at 14. I don't feel depression on it, but at times paranoia and anxiety at times, but it comes and goes and does not linger at all. I also have a shorter fuse to bust out mad as fuck, but I always tell myself a second after the outburst its just the Tren calm down it isn't that serious, I tell myself the same with the paranoia and anxiety. Btw the paranoia and anxiety are not from people it comes due to health, idk why but Tren makes every single weird feeling in your body exaggerated and when that happens I get big time health Anxiety / Paranoia combo at the same time. Seeing my new blood results now really puts me at ease now though, big stress off my back.