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+ 39 HCG What is it and When to Use It

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HCG and When to Use It

A lot of cycles recently have HCG in them and I think that we must understand exactly what the purpose of HCG is and how to properly use it on cycle and PCT. HCG is only used on long cycles or extremely high dosed cycles. Not on a Test only cycle lasting 12 weeks or stacking with another low dosed compound. 12 or more weeks and heavy dosages warrant the use of HCG. Let’s look at why….

Human Chorionic Gonadotropin (HCG) is a hormone produced during pregnancy that is made by the developing placenta after conception, and later by the placental component syncytiotrophoblast. Some cancerous tumors produce this hormone; therefore, elevated levels measured when the patient is not pregnant can lead to a cancer diagnosis. However, it is not known whether this production is a contributing cause or an effect of tumorigenesis. The pituitary analogue of hCG, known as luteinizing hormone (LH), is produced in the pituitary gland of males and females of all ages.

HCG is clinically used to induce ovulation and treat ovarian disorders in women, as well stimulate the testes hypogonadal (underproduction of testosterone) men. It is also used in the treatment of undescended testicles in young males called hypogonadism. HCG in males is similar to LH, because they are similar and LH binds to receptors on Leydig cells stimulating synthesis and secretion of testosterone, the use of HCG is an added bonus to steroid users even if there is a lack of endogenous LH. Since HCG increases the body’s natural testosterone levels, its use during long or extremely high dosed cycles can be most beneficial were the effects on the hypothalamus causes a depressed signal to the testicles. The result of the depressed signal leads to what is known as testicular atrophy (shrunken nuts). The use of HCG will send an artificial signal to the testes (again, as if it were actually LH), thus preventing (to some degree) atrophy. It not only helps to maintain testicular size and condition but it will also help in restoring testicles back to their original size. Restarting natural testosterone production as quickly as possible is extremely important in regulating our hormones back to its normal balanced level.

Now how to dose it….

Any more than 500IU of HCG per day cause too much estrogen aromatase activity. There is a theoretical belief that aromatase is actually toxic the Leydig cells of testes. Understand you are inducing primary hypogonadism (permanent) and treating steroid-induced secondary (hypogonadotrophic) hypogonadism (temporary).

250IU or 500IU on two days each week while on cycle is the usual dose to combat testicular atrophy, if it isn’t enough then use it more days each week at the same dosage rather than raising it because of the aromatase activity involved with doses over 500IU. Usually you start the HCG 2 weeks after you start your cycle and you can start it at the mid-point of your cycle until you finish. I always say let your body be the judge. You know your jewels better than anyone. If there is significant shrinkage compared to your usual, then its obvious.

At the end of the cycle after one week you can stop and the next week start you PCT
If you decide to use HCG in your PCT it is the same dosage of 250IU or 500IU for 10 – 14 days and stop. The testosterone production it induces will cause issues with recovery because it will continue to suppress the Hypothalamic Pituitary Testicular Axis (HPTA). This is where the standard PCT picks up and finishes the job making your cycle successful and complete.

Dosages for mixing:

Bacteriostatic Water for dilution is used.

5000IU/10ML mixed HCG is dosed as so below. Same thing if it’s a 10000IU/20ml mixed vial

250IU is 0.5cc in the syringe (50 units in a insulin syringe)

500IU is 1cc in the syringe (100units in a insulin syringe)

My goal is to educate the community so that we have abetter understanding of what things are and how they benefit. As always its your forum so you input is always welcome. Thanks for reading

mjh36's picture

Ok got it, thanks. Should I gently swirl it around a little after I put the bac water in?

mjh36's picture

Awesome, thanks for the info Ace!!

Yates's picture

My girl has some questions:

"Usually you start the HCG 2 weeks after you start your cycle AND you can start it at the mid-point of your cycle until you finish." -- So say for example, I start a 14-week cycle on September 1st, am I supposed to start the HCG 2 weeks after the start date (i.e. September 14), OR on the 7th week which is the midpoint of my cycle?

"If you decide to use HCG in your PCT it is the same dosage of 250IU or 500IU for 10 – 14 days and stop."
-- what's the interval for the doses? 250IU or 500IU for 10-14 days everyday? every other day? 2 days a week?? Please clarify.

Yates's picture

thank you so much, that was a great help . it was driving me crazy.. before.

jonnybravo126's picture

hi could anyone help me in regards to hcg please
its been about 15 years since I really did my last big cycle
im dipping my toes back into the water and wow a lot of things have changed in regards to how to use it
the guy who used to own the gym I went to sold everyone there stuff
he ran guys on a six week cycle (standard stuff like sus or testex and deca) and then for the three weeks after it would be one shot of 1250 hcg once a week there after

so anyway
its all new to me the idea of running hcg during cycle
what is the protocol in regards to mixing and storing it?
I can get my hands on the singular 5000iu amp with saline.
do I mix that all then store in the fridge?
im going to be starting a 12 week cycle of 500mg of test prop a week and 35mg of dianabol a day

the missus wants to start trying for more kids soon so my bollocks working properly is a high priority

cheers guys

Jdp420716's picture

good artilce... thanks whoever posted it

HydeMind's picture

I just got some hcg in, I ordered kind of late in the cycle but hoping to get the ole boys to hang low again. Good write up, thanks

Mars's picture

there's not much else to say that hasn't been said already. Thank you bro! Thank you. Great post +1

B52-BODY's picture

save for later - excellent !!!

mikebuie's picture

quick question for you big brother - im wrapping up my first cycle of test e (250mg 2x week) which i kickstarted with 35 mgs dbol for 5 weeks. it shut me down pretty bad and my boys have lost probably half their size almost. i have hcg on hand but was originally planning on using it for my next cycle (test p and e) starting in early summer. i have 2 pins left before completing my cycle and my question is whats your take on the whole "blast phase" is when it comes to hcg and cycle ends. thats really my only option left at this point in time due to incredible poor planning and jumping into something without truly having a grasp on all that is AAS, but thats another story and a mistake i thankfully havent suffered from thanks to these forums and my thirst for knowledge. lemme know what you think when you get a chance big bro, thanks man

hollywoodham's picture

this should be a sticky post. great info

Owes a Review × 1
youngbb333's picture

I mix my 5000iu hcg with 1mL. For 500iu injection I measure 0.1cc. This save a lot of bac water lol!

HydeMind's picture

I DO THE SAME. I think 10ml as recommended in above thread is excessive. 50 units is a lot to inject if you are injecting sub-q!

Protocol: If you want to take 500ius dose then mix 1ml with 5,000ius then take 10 ticks at a time. This is a lot less liquid. The only thing you lose out on is the accuracy of amount injected. But I think this is a good trade as opposed to injecting 50 ticks at a time...

robbyd's picture

imma start doing the same thing and start saving some bac water ^_^ and making pinning easier. except imma put 2mL so I can withdrawl .1cc for 250iu.. haha thanks for the simple yet genius idea!

robbyd's picture

How does that work out for you? Do you always do this? Thanks =]

ironman86's picture

thanks for the break down, very helpful

wickeddre69's picture

Thank you for this. Great info for a newb like me!

Sumatra_Triangle's picture

I'm always impressed by the quality of information in your threads! everything started to click once I read it a second time. I read it a third time, and did secondary research and I'm wondering if its true you need somthing to counter act its effects now too>

vascular's picture

I'm running a Test E only cycle for 12 weeks - 500mg pw. Week 14-18 PCT of Clomid and Nolva. I have decided to implement HCG through Weeks 4-13 (500ius pw = 250ius pinned EOD) and a low dose of Aromasin (12g pw = 6.5mg tablet EOD) Weeks 4-12.

I've researched a fair bit on HCG and its application and to be honest, it still remains contraversial to an extent IMO. Some believe HCG is overkill for a Test E only cycle at 500mg (relatively low dose in comparison to harder cycles with multiple compunds) and 12 weeks (also considered relatively a modest duration). Why? Basically it adds complexity when the aim of the cycle is to better understand your body's reaction to a less complex set of compounds. Note HCG does aromatise - hence adds complexity!!!

However, many also believe that controlled doses of HCG in ALL of your cycles (regardless of dosage or duration) bodes well for 'longevity' as an increasingly heavier AAS user evolves overtime. These groups believe that HCG in all cycles is a pre-emptive strike against possible test or testicular abnormalities later in life.

In the end I still think cdaddy7's post above is 100% accurate. But I'd also like to go out on a limb here and say that I think the benefits of ALWAYS running HCG in every cycle (regardless of its milder design) has benefits over the long run. And I'm seriously intending to run HCG even on my first cycle

However I'm a noob. Am I mis-informed in my research???

Is it wiser to simply sit out HCG on the first cycle and see how my balls react first after PCT???

Being a perfectionist is working against me.

SexWeightsProteinShakes's picture

i am glad i came across this. i was wondering why everyone doesnt add hcg into their cycle even if it is just test. i am thinking of starting my first cycle just like this. from everything i have been reading it seems that hcg is a good addition to all cycles. do you happen to have a cycle log for this exact one?

b.mo254's picture

I believe that HCG is a great idea anytime your LH is suppressed. I wait until I'm a couple weeks into a cycle before I start using 100units/day. My nuts stay pumped, and pct/recovery is easy. I got this dose from some research article that I read a long time ago, that said 100 units was shown to be effective yet not burn out leydig cells.

vascular's picture

What is 100units? iu??

b.mo254's picture

Sorry, I meant to post that in reply to the main post. Yes, iu or international units.

Liquidex's picture

I were always wondering, if its necessary to start the HCG at the begining of the cycle?? I wonder if you can use it say mid-end of 12 weeks cycle, like during 8~12 weeks?? Any reply is appreciated!

macklroy3's picture

This helps me a lot. I'm unfamiliar with HCG. Thanks for the info dawg. Although you could have deciphered in Layman's Terms!

macklroy3's picture

That's my Uncle Zewi! That's the jist I got from it... but just making sure!

Carlos Danger's picture

My dogg! Ok love the post but all my hcg vials have been 2ml vials. I add 2ml Bac water and each 10u it's is 250iu. 1ml of Bac makes it 500iu for every 10units. It's just math.

Carlos Danger's picture

Its the same math u are using just on a smaller scale. Keep killing it brudda! U making me proud

Dyl_Pickle's picture

Thanks for posting this. I'm about to finish my first cycle and I'll be using HCG here soon!

MASSIVE48's picture

Bravo bro great info! +1 from me!!

OneBanger's picture

Great Thread Man +1 from me

P's picture

Another great write up.
+1
Also, since hCG has a high estrogen aromatise activity level I would include the use of an AI on cycle