I am sure this has been discussed ad nauseam, however, I have encountered many who have asked this question. I would like to first state that I keep my bac water in the fridge along with my vials of GH so everything is the same temp when reconstituting. I have learned the hard way a few times so this is the process that I take when reconstituting.
I like to reconstitute by first sticking my slin pin in without plunger to decompress the vacuum. Once that is done I fill a slin pin with 1cc of bac water and hold my vial of gh upside down and slowly inject the bac water in the vial keeping it from the gh until I have finished. Then I flip the vial right side up and pull pin out. This method helps me mix it without damaging the gh and also avoiding floating chunks that need to dissolve. Once you have mixed it and it is clear, you can then suck 1cc of air out the vial to re-establish a vacuum in the vial. This helps to avoid a stream of reconstituted gh from spraying out the first time you draw your first dose from positive pressure. I speak from experience and have watched a few IU fly out the rubber stopper when I pulled my pin out. LOL
As far as dosing I would start at 2 iu per day in the morning so you dont interrupt you natty night pulse and work your way up to as much as you can handle. Once you are above the 3iu mark you might want to research the synergistic effects of T4 and dose it at 10mcg per iu over 3iu. It is my understanding that you should only run 5iu or more per day while on cycle and then go back down to a lower dose while off cycle. Usually the cruising dose is some where between 2-3iu. I hope this helps.
O.S.