I have had this exact issue but with another very well known generic brand used by many here on eroids. First vial nothing then second vial large big red itchy welts appeared with a hard lump forming in the fat layer. They took 5 days to go away. Third vial the same. Moved to IM pinning and I have zero problems.

I spend some time researching and chatting to a few members and a doctor here and a few things came up:

• apparently 1 in every 100 can be allergic to rHGH no matter what brand
• there could be an allergy to something in that specific brand. Using another brand will answer the question
• some individuals have an "allergic reaction" due to the particular reaction of fat tissue to PH of the solution injected and that's why they're OK with IM injections
• even when injecting IM you have the same reaction but it is less severe and not noticeable since its deep
  IM and the blood flow is better

Not sure bag helps you but switch to IM and see if to still have issues and try another brand (I'm doing his next week to see when it arrives.

I have the same problem. some vials are ok but some gives red itchy welts