Myostatin Antibody (Ab3239-I)
Ive been doing some reading and yes, folli works well if you buy the right stuff, so do all of the other inhibitors, but one thing ive yet to come across is someone experimenting with an actual antibody like ab3239-I.
ab3239-I has the ability to cause a very long term reduction in myostatin by making the body (in theory) produce its own antibodies according to some studies ive read into (kind of a stretch to say but somewhat the same idea as a vaccine). its also about the same price as human grade Folli and can only be purchased from actual labs.
what are your thoughts? strictly from an informative viewpoint, of course, there would be repercussions to doing this if it actually worked over a very long term, the belgian blue bull has severe limitations because of its muscle mass for the very reason that this would be plausible in humans.
Anyway, just looking ton spark up some conversation and get some input from other more knowledgeable members.
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trenandmentmaybe this is the camel crews secret
If a scientist synthesized an inhibitor it I'd sign up to test it
You pointed out yourself the bull has/had serious complications that you would deal with for life. Antibodies don't really go away, they go dormant and there's a small chance theoretically they could be eliminated but we're not there yet. If you were to do something like this it would most likely be with you for life. It's been theorized that without myostatin it's possible to get big enough to literally tear in half. Also if your not 280-300 pounds then you shouldn't even be tossing this idea around.
Maybe i wasn't clear enough, im not considering the idea, im just curious to know what everyones thoughts are on it. i understand the issues that would and could arise for sure but its stil plausible i think.
I suspect they've begun doing things like this at oxygen. It would essentially be an expirement on ones self. Have you seen the videos of Ramy being unable to breath while he walks around? Plausible sure, foolish most likely.
Highly unlikely. The science isn't quite there just yet. Now legit igf this I know from a very reliable source.
We have bulls and rats running around yoked to the extreme so yeah the sciences there. It's just not safe or ethical for humans, and there's also no clinical need that I could ever think of.
lol those bulls and rats are genetically myo deficient. Myo is released in the body 24hrs a day. There isn't anything available which would allow the human body to consistently block Myo. I know they are looking into some kind of vector virus which would theoretically allow constant blocking of myo, but the research is currently in its infancy stages. So yeah the science isn't there just yet. We can rest assure the camel crew isn't playing this game just yet.
Lol your last sentence
You are correct in that they selected and bred animals lacking myostatin and I do remember the virus thing. It's been a minute since I came across this topic but apparently they've made some strides. Check these out and tell me what you think.
http://www.sciencedirect.com/science/article/pii/S2213858715002983
https://www.ncbi.nlm.nih.gov/m/pubmed/26980371/
There's a few more I'm looking at today after I cut the grass, but apparently this thing has gone through multiple phase 2 trials and looks like phase 3? May be safe too in contradiction to my previous thoughts/comments.
Don't forget though, we have new guys taking handfuls of anadrol for months on end, deca only cycles and a gram and a half of tren for 'cutting'. I would say clinical need or not, given the money to burn, there are plenty of guys out there who wil do anything to overcome what they think is bad genes when in all actuality, is actually bad training/diet
although I do like that line "plausible but foolish" this would likely be true though we don't have any long term studies. Sure, blue bulls are fine but they're likely adapted to it. We done successful testing on rats but they're lifespan is so short it probably wouldn't be much of a problem, not enough time alive to really see the issues that we could speculate anyway.
Does show promise for people with sever muscle wasiting diseases but that's only to say that the body wouldeither correct itself or find some sort of homeostasis
I agree with pretty much everything you've said, in particular the drug abuse instead of hard work. When I say clinical need I'm speaking strictly from a medical viewpoint and not a PED user. I'll have to revisit this topic because I thought there were severe complications with test subjects but maybe they've advanced since then. As far as muscle wasting that would be entirely dependent on if myostatin was responsible which I think is virtually non-existent, not sure this would help other conditions of that nature since myostatin typically plays no role in this disease conditions.
It would definitely be an intriguing tool to add if there was a way ti utilize it safely.