Makwa's picture
Makwa
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+ 6 IGF1-LR3 Dosing Protocol

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I’ll be incorporating some IGF1-LR3 into my cycle and I have kind of seen dosing protocols all over the place from my research. So anyway, this is what I have in mind for my dosing protocol and would like to get some feedback if I am totally off base or if you have a certain protocol that has worked really well for you. I should also mention I will have 5iu daily of HGH going on at the same time.

I kept flip-flopping from 50mcg to 40mcg and I think I have finally settled on a dose of 40mcg. I plan on taking it Post WO and my routine involves 5 workouts/wk with 2 days off. I didn’t plan on taking it on my off days so I would be doing a total of 200mcg/wk which would give me exactly a 4 week cycle of it with each kit. My plan is to cycle it in 4 wk intervals.

Now the 2 burning questions I have here are:
1. Is 40mcg not enough or too much from your experience?
2. Should I also be taking a dose on my non-workout days, or maybe a lesser dose?

So to sum things up, what I have planned right now is 40mcg subQ post workout and nothing on non-training days. So let me know what you think of that or if there is a better way.

Also, what are your thoughts of timing carbs with the IGF dose? Opinions on that seem to be all over the place also.

xsawgnr's picture

Can any one direct me to the best source for IGF?

Thanks

addicted.to.pain's picture

dude it is against the rules to mention sources in open forum. You have been here for five damn years how do you not know this?

Cgkone's picture

That's probably too much if its legit

5percent4life's picture

2 years late yo the party. But what about 40mcg pre and 40mcg post on big muscle days like back and just 40mcg post on small muscle days

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Dacky's picture

I think 80mcg of legit and accurately dosed LR3 is a big dose. I would be worried about intestinal growth at that dose.

I have recently been experimenting with a pre workout dose of DES (20mcg once fully warmed up and about to start my working sets on first exercise of the day) followed by LR3 (30mcg) post workout with a good dosage of fast carbs (30 to 60g). I’ve loved this combo and although I am in a mild deficit I swear I can see some muscle growth after a 4 week cycle of this).

Makwa's picture

worth a shot at trying

TheFlash85's picture

Spot injections into the muscles you just worked, then smash a 50:50 ratio of protein and carbs aswell as bcaas- powders for quick absorbtion- then an hour later have a big meal the same heavy in carbs and protein.

melone's picture

I followed the protocol from Grunt76 (http://anabolicminds.com/forum/igf-1-gh/52017-my-take-igf.html) for ~2 months during my last bulk (test/bold/tren/mast). Was my best bulk ever, but it's impossible to tell what part of my cocktail contributed most. I think meanwhile that the IGF-1 (with some MK-677 & CJC-1295 with DAC) had a significant contribution.

The protcol is 20mcg bilateral (=40 in total) post workout intramuscular in the trained muscle, but not more often than EOD (if you train every day). Nothing on the non-trainings days. The reasoning is quite good describend in the thread - that the IGF-1 receptors are upregulated a short time post WO and that we can target them with IGF-1 lr3 directly after WO, with a dose small enough to not hit the IGF-1 receptors elsewhere, like in the gut.

To your questions:
1.) for me at +/- 200 lbs, 40mcg post WO was enough for the small muscles. But, 40mcg is the lower range - a dose that will work and will likely not affect your gut. For the legs, I increased gradually up to 80mcg.
2.) Following the protocols of Grunt76 or Dave Palumbo, 40mcg post WO + an eventually smaller dose on non-training days will downregulate your IGF-1 receptors. I would say that this could still work - but you would have to cycle the IGF-1 LR3, maybe 4 weeks on / 4 off. On the Grunt76 or Dave Palumbo (11mcg every day) protocols you can stay theoretically forever, with the reasoning that on the first protocol, your receptors can recover during the non-training days while you don't pin more often than EOD, while on the second protocol you just keep the daily IGF-1 LR3 dose very low and avoid this way downregulation.
3.) Timing carbs - I've seen once a post of somebody measuring his blood sugar level every hour after 10mcg IGF-1 LR3 (can't find the link anymore). This is easy for everybody to repeat. He was showing that for the next ~8 hours his blood sugar remained rather low despite several meals. I take out of that that timing carbs is not very important as long you just eat enough in the next hours after training.

Makwa's picture

Very interesting. Thank you.

Dacky's picture

50mcg post work out in the evenings sub q with a bunch of fast digesting carbs was the sweat spot for me. Ran 4 weeks on 4 off etc. Had excellent gains that way on my last bulk (test/bold/drol). I wasn't running HGH at that time. I continued into PCT and added HGH and didn't loose anything until about 8 weeks when I got sick and couldn't eat or train for 4 weeks. Game changing stuff in my view.

Serg Feltersnatch's picture

How quickly post workout? Should I put it in my gym bag or wait the 15 min drive home?

Dacky's picture

15 mins is perfect and saves you the hassle of worrying about keeping it cool while at the gym.

Makwa's picture

Did you start out lower or hit 50mcg right off the bat?

Dacky's picture

Off the bat!

Makwa's picture

were you getting the massive pumps that everyone seems to be talking about?

Dacky's picture

Yes the pumps were quite intense but more so on the couple of times I ran it pre workout.

Makwa's picture

Did you experience any hypoglycemic effects taking it pre WO without a meal right away?

Dacky's picture

Not quite but I did get extremely hungry and craved carbs if I didn't use them. I guess I may have felt the early warning signs of going hypo but I never let it go full blown.

Makwa's picture

I might have to carb up good if I try it pre-WO. Went hypo once before and got all glassy eyed and pale looking wandering around not knowing what the hell was going on.

Serg Feltersnatch's picture

In your opinion, is it ultimately more beneficial post workout or does it not matter pre or post workout?

Makwa's picture

I prefer taking it pre Workout. Due to the systemic nature of the lr3 I want to have it in my system while the receptors are being up-regulated during training. It is basically there as soon as the receptors are triggered and it can do its job. The big question which I don't really think can be answered is this better than taking it post workout after all the receptors are ready for it? Probably six of one and half a dozen of the other. I do like the extra pump it provides when taken pre. Now with DES that I would be pinning in the gym bathroom immediately after training.

Wheetees's picture

What caused this?

Makwa's picture

Low carbs during my prep and overdoing cardio.

back40's picture

When i ran igf at 40mcg and pulsed hgh 4iu it gave me a wet look.
I pinned the igf im pwo into the muscle trained. 3 on 1 off.

back40's picture

gains were modest. good pumps as mentioned above. for me It depends were I'm at, and what I want to accomplish. Hgh if I had the cash, I would do again. IGF...meh.

Makwa's picture

I'll take the wet look if it ends up with some lean body mass. What type of gains did you get from it?

PPGfreak's picture

I ran 20mcg for two weeks and then went up to 30mcg. I might go 30 and then 40 next time because the body does adapt to it rather quickly. But if I'm getting good benefits off of 20 I don't see any reason for me to move it up to 40 or even 50.

Makwa's picture

Were you doing pre or post workout? Subq or IM?
Good gains from it?

PPGfreak's picture

The pump/workout I get from it makes it worth every penny. Definitely lets me push my self farther than normal. I can't exactly identify what games I've made from it. I started at one month into my bulk cycle so it's hard to say what strength are size is coming from the IGF or the gear....

PPGfreak's picture

I'm doing IM pre workout. I've hear post workout is better but I enjoy the pump to much to try it lol

Makwa's picture

The half life of LR3 is supposedly 24-30 hrs so I wonder if some would still be floating the next day before your workout.

PPGfreak's picture

More than likely but a very small amount unfortunately :(

Mrcoolbeans's picture

Im definitely not experienced with using this, as Im doing my first cycle or igf-lr3 myself right now. As far as research goes and what Ive read, sounds like your right on the money. Ive heard it all, 10mcg before and after is what (dave palumbo ) recommends so thats onyl 20mcg a day which is very low compared to others places Ive read showing all the way up to 100mcg a day. But from most research Ive done, I see 40mcg to 50mcg being the most popular. My self, Im doing 20mcg before and 20mcg after training, and yes i know doing it before probably isnt doing me much.
As far as your off days, 99% of the time ive read that you shouldnt taking any on the off days, which Im also following suit. (2 days off) This seems to be working good for me so far, Im getting very good pumps, feel huge in the gym but again, that could be from the crazy amount of carbs Im eating and test/npp im taking lol
I think your plan is perfect, 4 on 4 off, 200mcg a week/40mch a day.
And carbs, thats where Im not sure of, I still do the usual post shake within 15 mins, then a good sized meal within an hour of the workout(50 carbs/50 protein) roughly.
Lastly since your running hgh, the igf protocol could be way different since your on 5ui of hgh, or it could be the same. Anyone else know about that?

Makwa's picture

It sounds like the lower dose may be the safer way to go. I guess if there is to much still floating around due to taking to high of a dose all it does is attach to the receptors in your gut and make your intestines grow. Need to find that happy medium dose for the best bang and least amount of sides.

Mrcoolbeans's picture

I have also read thaty, about taking too much and some getting attached to your intestines. Which is not what we want at all, thats why i felt ok with 30-40mcg each training day. Id say 40 is safe, 20 is safer but everyone like you stated previously, heard a million different things.

joey_ragz's picture

Just based off of my experience (which I'd say was pretty good) I'd start lower and work your way up. I've done quite a bit of research on it and have found that 4 out of 5 people will say anything over 50 mcg is just a waste.

I'd start lower maybe around 20 mcg because it's not like doing a smaller dose will cause it to go to waste and if you end up noticing you like it and can get away with a lower dosage than why not?

Like I said in another previous post I noticed at about the 3 week mark my body started to get used to it so I needed to up my dose. If you start lower you'll have more room to work up with.

Makwa's picture

Now another million dollar question is if it is better to run a lower dose longer or stick with a higher dose for a shorter time?

TheFlash85's picture

Same dose throughout. No need to taper up or down.

joey_ragz's picture

Well like PPG I used it preworkout and you could literally feel the pump it was amazing so shit if you can get away with doing 20 mcg for 3-4 weeks then I'd just keep it there. If around the end of week 2 to the beginning of week 3 you start to feel it dropping off you can bump it up to maybe 25 to 30 mcg to ride it out

Are they 1mg vials that you have? Are you reconstituting with bacteriostatic water or acetic acid?

Makwa's picture

200mcg vials. Reconstitution with bac.

joey_ragz's picture

Oh ok gotcha. If it starts to feel less potent towards the end let me know and I'll tell you how to make acetic acid so it stays preserved for longer. You know what you're doing though bro you can just feel your way through it. You should notice something immediately so you can gauge your dosage based on how you're responding. One thing is for sure though, that coupled with the gh, will make you tired as hell. I did have to drink some black coffee mid day just to keep me awake from time to time.

Mrcoolbeans's picture

You make a good point on starting lower, I have read that myself.
Could always do something like this.
weeks
1-20mcg a day
2-30mcg
3-40mcg
4-50mcg
Or you could be lucky and blow up on 20mcg a day and just stay there lol

But for me I started at 40mcg and didnt notice any bad side like
Dizziness
Drowsiness
Depression
Sweating
Palpitations
Tremors
Headache
Slurred Speech
Inability to Concentrate
Anxiety, I have normally and still havent got to much of that.