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+ 14 GHRP's & GHRH's

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Preface
AAS (Anabolic-Androgenic Steroids) as we already know are great performance enhancing compounds, in much the same way that HGH (Human Growth Hormone) is a great compound. Both of these compound work great separately, however, once these two compounds are combined, the result is synergistic of each other.

This is because (on the basis of a two dimensional) HPTA (Hypothalamic-Pituitary-Testicular Axis), where one side is testosterone levels and the other side is growth hormone levels....like a see-saw....our body naturally tries to balance this axis, this is called homeostasis. When we are on cycle or blasting with our body with higher than normal testosterone levels, then the see-saw becomes to tip to one side and the axis becomes lob-sided.......so what does your body try and do?.......create homeostasis and balance testosterone and human grown hormone again. But there's a problem, your testosterone is way to high since your injecting copious amounts, but your growth hormone cannot rise and keep up with your body's testosterone.....so for your body to reach homeostasis, it must remove testosterone, which is counter-productive.......how does your body remove extra testosterone?.......well there are a number of ways, some testosterone is binded to your SHBG (Sex Hormone-Binding Globulin), some is converted to estrogen and some is wasted. Now at this stage your body has reached its goals of homeostasis, but you've wasted your time and money on buying extra testosterone, so what do you do?

To get the synergistic benefits (1 + 1 = 3) of testosterone and growth hormone, you must increase the concentration of both hormones in your body so that the axis doesn't become lob-sided. This means that a limited number of testosterone is wasted and a limited amount of growth hormone is wasted.

Hold on a second........since growth hormone is a relatively expensive compound, why not try GHRP's and GHRH. Despite their mnemonics, what they actually do is stimulate natural growth hormone production, where GH supplements your bodys growth hormone production.

A closer look at GHRP's and GHRH's;

GHRP's & GHRH's

GHRP = Growth Hormone Releasing Peptide
GHRH = Growth Hormone Releasing Hormone

Types of GHRP's and their function in the human body:

GHRP's release a pulse of GH in the human body.
  • Hexarelin: A first generation messy compound.
  • GHRP-6: A messy compound, since it induces a wide array of sides other than a pulse of GH. These sides include intense hunger and gastric mortality, while also effecting cortisol and prolactin. This is a first generation GHRP.
  • GHRP-2: My personal preference (alongside Ipamorelin), a second generation peptide, which is much less messy than GHRP-6, with the added benefit of a greater GH spike. No gastric mortality and marginally less hunger with GHRP-2.It can also have an effect on the normal range of your cortisol and prolactin levels.
  • Ipamorelin: Not a messy compound at all. A third generation peptide. It does not release as much GH as GHRP-2, but causes little hunger or gastric mortality and also has little effect on cortisol and prolactin.
    Types of GHRH's and their function in the human body:
GHRH's amplify the GH pulse which GHRP's release.
  • Mod GRF (1-29)
  • CJC 1295 (w/out DAC)
    It's not necessary to alternate every 2 weeks although you can. You could alter every pin. On the basis of pinning 3x a day i would recommend (remember to always shoot up peptides on an empty stomach):

There is a pattern in the way i layed out the GHRP's...they're in chronological order, whereby the last, Ipamorelin is a third generation peptide and the most cleanest, while Hexarelin is a first generation peptide with the most messied results. If you're looking for the hunger benefit then i would opt for GHRP-6 - i currently use GHRP-2 and find that occasionally i begin to shake once ive injected the peptide - and since you have experience with this compound already then i would suggest GHRP-6 and then if you find the results aren't sufficient enough, then i would once again take the leap onto Hex. Hex sides will be amplified from the sides of GHRP-6.

Also if you look at these graphs you can see the synergistic effect both peptides have in relation to natural GH secretion;

This picture below looks at the individual effects of each of the peps have on the secretion of GH in elderly people and also looks at the synergy both have, while also modifying the ratio of GHRP-2 and Mod GRF (1-29).

The graph below shows that pulsing your GHRP-2 and Mod GRF (1-29) has a greater affect on your natural GH production than a continuous flurry of GH secretion.

"One difference between GH peps and GH is that injectable GH stays active in the body for much longer...probably 4X longer, but at the same time, injectable GH does not result in a very large spike (compared to GH peps), unless the dosage is very high. GH peps result in a large burst of GH which lasts for a shorter period of time than injectable GH, but the spikes are much higher...anywhere between 2-10X higher, depending on the dose of both the GH peps and GH."
"For example: A single 100 mcg dose of GHRP-2 & modGRF1-29 will result in a GH spike about 2-3X higher than a single 7 IU dose of injectable Gh administered all at once. However, this 7 IU inject will last stay active 3-4X as long as the GH peps. How long GH remains active in the body will have a considerable impact on its effectiveness. This is why a 7 IU inject of GH will crush a single 100/100 mcg inject of GH peps."
Steroid Insight

Dosing protocol's are entirely goal dependent as i shall explain;

There are 7 dosing methods that can be used with these peptides;

Method 1 - Minimalist Anti-Aging
If your goal is to gain the anti-aging benefits received from GH then a dose below saturation will suffice. A recommended dose of 50mcg of both your selected GHRH and GHRP will give you this benefit. You will also experience better sleeping patterns and you will stay in the sleeping cycle stage which will promote recovery.

Method 2 - Saturation Dose Pre-Bed
To improve on the anti-aging benefits you received from the first dosing protocol, you can now run the peptide combo at saturation dose. The benefits from this include following the natural body GH secretion patterns and your youthfulness will increasingly pronounced. Thus resulting in a better overall health, wellbeing and recovery.

Method 3 - Saturation Dose Post Work-Out & Pre-Bed
Not everybody will gain better sleep from the above 2 dosing methods. This is because they are sensitive to Hexarelin and GHRP-6, if they would like to ensure they receive better sleep then a pre-bed dose of either GHRP-2 or the much more refined Ipamorelin will provide this.

Furthermore, the post work-out dose will serve your protein metabolism and improve protein synthesis. A saturation dose will see results such as injury healing, well being, anti-aging and an increase in muscle mass.

Method 4 - Saturation Dose Morning & Post Work-Out & Pre-Bed
This method includes a morning dose, which in a fat-loss mode will increase the release of fatty acids, which will subsequently be used as energy for your upcoming cardio session. Additionally, a 3x a day dose will ensure your body is in an anabolic state.

Method 5 - Higher Than Saturation Doses
This dosing protocol is entirely subjective, since a higher than saturation dose can cause a desensitization to GH release. Also, a higher than saturation dose may bide well by people, since if their peptides are manufactured to sub-par quality and are in fact under dosed then a seemingly higher than saturation dose will yield saturation dose like effects. As you can see from the graphs above, there is a benefit from using s higher than saturation dose, however, it is in line with the law of diminishing returns and the saturation dose will provide the most efficient results.

Method 6 - 4+ Saturation Doses
A dosing protocol of 3x a day will see your body's GH levels not being wasted at all. However, a dose of 4 x a day will be used for those wanting to gain even more muscle mass and more GH benefits than a protocol of 3x a day. This is for the serious GH fiend, since pinning yourself 4x a day is a job itself.

Method 7 - Variable Dosages + Growth Hormone
A dose post work-out at saturation dose of the peptide combo in addition to a GH dose of 2.5IU 5-10 mins after your peptide dose will see your body receive a huge GH pulse. An additional peptide combo dose pre-bed is also recommended for extra GH benefits.

By saturation dose, we mean 1mcg per 1kg of body weight - the aforementioned saturation dosages are based on a 100kg human, which equals a saturation dose of 100mcg.

Information extracted from DatbTrue.

Below is an improved dosing protocol, maximising the benefits from the use of the most effective GHRP's.

Morning (dose 1): GHRP-6 (or Hex) w/Mod GRF1-29 in morning. This will help extend the gh release you were having from rest and keep your appetite up in the morning.
Gym (dose 2): GHRP-2 w/Mod GRF1-29 post workout and then proceed to eat a huge meal. This GH boost will be very effective at this time and the large meal will be great for adding size.
Night (dose 3): shoot Ipamorelin w/Mod GRF1-29 for an extended GH release.
I wouldn't recommend Hexarelin, simply because it's a primitive GHRP and since there's a very limited cost associated with these peps then i would certainly thing about buying some GHRP-6, GHRP-2 and Ipamorelin and use them in the way i described them above.

See:

How To Reconstitute Mod GRF (1-29) Peptide (Step-by-step guide w/Pictures!)

How To Reconstitute GHRP-2 Peptide (Step-by-step guide w/Pictures!)

Step-by-step Injection Guide: Subcutaneous (SubQ)

Hercules_KB's picture

the link isn't working can you fix it please ?

Diamondgirl's picture

How would someone pin if the post workout meal is the las meal and go to be right after?

sic26's picture

U mean last meal b4 bed if yes I used to wait hour then pin.

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Diamondgirl's picture

Post pin right after workout, meal, then pre bed pin an hour later? Nothing wrong with the time span from my first pin being 4:30-5am and next being 8pm and 9pm?

sic26's picture

Sorry for taking long to respond was outside with son I posted link so if u wanted u could write the different ways to run it

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sic26's picture

U should space it out 2 3 hours

Owes a Review × 1
manbearpig's picture

How long should someone wait to eat after pinning ghrps? I heard you are supposed to wait a little because high carb meals blunt gh release.

sic26's picture

The hunger pains I get is crazy guess i will get use to it.

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PIN_CUSHION's picture

I've been reading 30 mins minimum.

lo's picture

Awesome post bro very informative I'm going to send u a F.R.

Denser's picture

What a great post. Kudos!

LGM's picture

Great post! Lots a good info there!

Random Guy's picture

Is there any benefit to be gained from splitting the post workout dose (Dose 2) into 50mcg pre workout and 50mcg post workout?

Edit: not sure if its my browser but the graphs above are not showing

P's picture

It's entirely goal dependent as i shall explain;

There are 7 dosing methods that can be used with these peptides;

Method 1 - Minimalist Anti-Aging
If your goal is to gain the anti-aging benefits received from GH then a dose below saturation will suffice. A recommended dose of 50mcg of both your selected GHRH and GHRP will give you this benefit. You will also experience better sleeping patterns and you will stay in the sleeping cycle stage which will promote recovery.

Method 2 - Saturation Dose Pre-Bed
To improve on the anti-aging benefits you received from the first dosing protocol, you can now run the peptide combo at saturation dose. The benefits from this include following the natural body GH secretion patterns and your youthfulness will increasingly pronounced. Thus resulting in a better overall health, wellbeing and recovery.

Method 3 - Saturation Dose Post Work-Out & Pre-Bed
Not everybody will gain better sleep from the above 2 dosing methods. This is because they are sensitive to Hexarelin and GHRP-6, if they would like to ensure they receive better sleep then a pre-bed dose of either GHRP-2 or the much more refined Ipamorelin will provide this.

Furthermore, the post work-out dose will serve your protein metabolism and improve protein synthesis. A saturation dose will see results such as injury healing, well being, anti-aging and an increase in muscle mass.

Method 4 - Saturation Dose Morning & Post Work-Out & Pre-Bed
This method includes a morning dose, which in a fat-loss mode will increase the release of fatty acids, which will subsequently be used as energy for your upcoming cardio session. Additionally, a 3x a day dose will ensure your body is in an anabolic state.

Method 5 - Higher Than Saturation Doses
This dosing protocol is entirely subjective, since a higher than saturation dose can cause a desensitization to GH release. Also, a higher than saturation dose may bide well by people, since if their peptides are manufactured to sub-par quality and are in fact under dosed then a seemingly higher than saturation dose will yield saturation dose like effects. As you can see from the graphs above, there is a benefit from using s higher than saturation dose, however, it is in line with the law of diminishing returns and the saturation dose will provide the most efficient results.

Method 6 - 4+ Saturation Doses
A dosing protocol of 3x a day will see your body's GH levels not being wasted at all. However, a dose of 4 x a day will be used for those wanting to gain even more muscle mass and more GH benefits than a protocol of 3x a day. This is for the serious GH fiend, since pinning yourself 4x a day is a job itself.

Method 7 - Variable Dosages + Growth Hormone
A dose post work-out at saturation dose of the peptide combo in addition to a GH dose of 2.5IU 5-10 mins after your peptide dose will see your body receive a huge GH pulse. An additional peptide combo dose pre-bed is also recommended for extra GH benefits.

By saturation dose, we mean 1mcg per 1kg of body weight - the aforementioned saturation dosages are based on a 100kg human, which equals a saturation dose of 100mcg.

Information extracted from DatbTrue.

Random Guy's picture

More good information, thankyou

TED's picture

wow learned alot! great post as always..cant throw you a +1 but air five! lol

humpnpump's picture

Good write up P, also note that these peptides are great for those in PCT as well in balancing the axis and getting the natty production working properly. I notice a big differnce in recovering natty when using GHRP or HGH during PCT. +1

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P's picture

They are definitely valuable in PCT brother. From my personal experience they actually helped me gain weight in my PCT, while dropping my BF% and they also eased my recovery. A great combo in deed that should be more widely considered in cycles.

Pmob's picture

P you have the best post by far !! Thank you !!

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P's picture

Thanks brother, I appreciate it Smile

Random Guy's picture

Brilliant read

monsteronjuice's picture

good read +1