posted Tue, 06/05/2018 - 12:48
2548
TRT vs. AI curve questions
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For months I've had the exact same protocol and results. Subq injection Wed morning. 1/4 Anastrozol Thurs morning. Without fail every Sat evening I get pimples on my left temple and greasy face. When E is higher also reduced sexual performance. By Monday the oily face is gone and the zits deflate. Sometimes by mid Sunday.
What does the reliability of zit/grease cycle indicate about my absorbtion rate of the T, and can I use that to dose my AI at a better time? Thanks for your advice.
Age 40
Weekly dose 160
1/5 Anastrozol
Nothing else.
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Dave_61I would check and make sure your hormones, especially your e2 are within normal range. Im assuming you're using a long ester like cypionate, which shouldn't really cause much test fluctuations with weekly dosing. But, splitting your dose into 2 injections wouldn't hurt and may help.
If I had to guess, its probably from the fluctuation of hormone due to the single injection. Try the same dose split into 2 or 3 doses per week.
It tells more about enzymes in your body... 5ar and aromatase specifically. You are converting to estogen and/or DHT with speed.
Id be inclined to diagnose it and do bloods differently to the TRT timing to establish dose. Id be inclined to test estro and dht at their highest points (zit-fest presumably) as well as total/free T and shbg.
You need to know which hormones are in play here and at what levels, because you might in fact need a 5ar blocker or something like that rather than ai play.
I'm not entirely sure why your DR would have you at .25 adex once a week considering it's short half life.I have to assume as that half life tapers, its causing your levels to fluctuate, hence the clockwork acne.
Do you have any blood work? What's your estro levels? Arimidex should be dosed more than once a week.. sounds like your levels are fluctuating alot.
When my estro is balanced I don't get zits at all... But my diet is really clean too so.. Maybe try some benzoyl peroxide at night to dry up some of the zits, wash your face in salicylic acid twice a day..
I'm not super concerned about the zits, I'm hoping their regularity indicates a metabolic rate of the T and AI to suggest the best time to dose my AI. Day before injection, day of? Maybe even 48 hours after? Because day after isn't doing it for me.
Yeah my labs are ok. Free T of 21. Total like 840 I think. E was 41 (too high for my liking). Which is weird becosse my prior E labs were 21, and 35 before that with no change in my T dosage.
I'm going to split my shot into 2 weekly doses of 80mg and maybe skip the AI entirely?
Should be able to skip it with twice a week pins. I actually pin m/w/f for mine 50mgs each with a slin pin because I like it and that’s what works for me, no AI needed.
Frankly with properly run trt you should not need an AI. If you do it means you’re taking too much testosterone for your body and you need to scale it back.
Unfortunately some people aren’t as lucky as you and do require an ai even with the lowest TRT dose possible for them.
You think there are guys who need AI on 20 mgs cyp EOD? Or 10mgs ED?
I’d be very surprised. I know it’s variable but if you’re aromatizing it means you’ve got more test than you need, unless you have a condition where your body just aromatizes like crazy and you’ve got gyno, acne, and all the other symptoms from childhood on.
I can only go off what I have seen countless TRT doctors prescribe their patients on here an other forums. Have you got any proof to back up what you’re saying?
So for me my range is 100-150 mgs a week. Any more and I start getting high estro symptoms. I can go up to 250 on cycle with proviron to control aromatization.
When I was originally prescribed 200 I had acne breakouts even with arimidex. I attribute this to fluctuations from the AI dropping e2 then it rising again and back and forth. As I lowered my dose I found where my body needed to be. 100 is great, 150 is high end but still very minimal estrogenic sides. I’m sure I could get by on as little as 75 a week.
I’ve also observed others who’ve found their “target range” where they no longer need AI and most have been between 100 and 150.
I Agree, I can stay away from my ai if I split my test to twice a wk. I was having the same issues then my old trt doc recommended doing that and it worked for me but we are all different...