posted Tue, 04/26/2022 - 17:53
2670
P5P for npp and prolactin
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So I just started npp at 350mg a week with my test that's at 500mg a week. I've been dosing p5p from the day before my first pin at 300mg daily. I'm also going to increase my adex from .5 mon and Thurs to .5 mon wed fri. So my question is this if you've run npp and p5p in the past at what dose did you run the p5p and should I increase.
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bgukxllsIt doesn't even matter if its p5p or regular b6. p5p is simply a more "active" form of b6.. it makes for a slight difference but you're really overthinking it. if you take 300 mg, you should be fine. I know some that take 200 mg a day and are fine.
NPP/Deca is far easier on the PRG receptor than Tren.. at that dose, you're not in for too much trouble. HOWEVER, everyone responds differently.. in which case, improving the p5p /b6 dose can help, -- but if it doesn't, as some others may have mentioned, always keep caber/prami around for safety.
Also, Arimidex is good to have on hand but don't increase the dose unless you need to.
I just had to call you out on comparing "normal B6" to P5P
By regular form of B6 I am going to assume you mean Pyridoxine/HCL as this is what most supplement companies sell and call it B6. Which is simply a scam and will do absolutely nothing for prolactin. Most multivitamins use this form as it is cheap and put B6 on the label.
Pyridoxine needs to convert to P5P via the liver before it can even be absorbed by the body. The liver can only metabolize a very small amount to P5P and many studies have shown some people can not convert it at all. So this is where you piss out most of the inactive B6 before it has even converted to an active form of B6(P5P) which your body can absorb. There is no way your body will metabolize anywhere close to 300mg of Pyridoxine or even 200mg.
More importantly Pyridoxine hinders the enzymes that are required for your body to absorb P5P. So taking dosages 300mg of Pyridoxine will give you the same effects as someone with a B6 deficiency and no effect on Prolactin.
bgukxllsThat's honestly what i used to think but people I know as well as myself have had good results using just b6. Besides that, most clinical trials proving the efficacy of b6 in reducing serum levels of prolactin, they use Pyridoxine HCL..
I think you are thinking of Pyridoxal HCL. It's a less common form.. It's similar to the p5p form but without the 5 phospate. It is known to be significantly less effective. Infact, there's an actual study that shows what you're talking about, but in regards to Pyridoxal HCL, while showing the Effectiveness of Pyridoxine HCL.
The major difference I noticed is that with p5p you only need about 300 mg a day vs 1000 mg a day for b6.
I'm always open to learning more but definitely do not want to discount my own experience and all the dudes I know who use "regular" b6 with no problems. But yeah, if you can grab p5p , why not use it? Its a better form as you mentioned. I started using it myself.. but also had no problems with b6. I just find it easier to take less mg with the p5p than the 400 mg 3 x a day recommended by my doc for Pyridoxine HCL.
Byanymeans78Thanks man
bgukxllsyeah no prob
I would make sure you have some caber on hand. Great if the B6 works for you but I sure would have a proven backup in place like caber. Why are you increasing adex without increasing test. That is like 3x the dose of adex that most people need at that test dose.
Byanymeans78I was more so just thinking out loud on that front I mean it did manage at what i believe was at 200mg(.5 x 2 a week) of test being that I've increased 300mg and added something that does very little but does aromitize my thought process was it would need to be increased at least somewhat...
To tell you the truth here, I think you are jumping the gun trying to run a 19-nor. You need to get a lot more cycle experience under your belt before diving head first into a 19nor. You should know exactly how your estro responds to different doses of test and how it responds to stacking with other compounds that aren't a 19nor. You have barely learned how to swim and are jumping into the middle of the ocean. Stick with test and maybe an oral.
Byanymeans78And was more so going to make that choice in a few weeks... more so was asking about if I should increase p5p and what's worked for others in the past
RustyhookerSo without bloods as proof youre giing to crash your e2 and stop all gains?
popcorn passes
Byanymeans78See above.. as much as I want to I can't disagree with you rusty lmao
Rustyhooker.25e3d is normal starting dose with bloods proving its need.
be safe out there
7footgodi’m also curious about this.