bdavid21wnec's picture
bdavid21wnec
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+ 1 Subq for TRT

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I have been reading up on Subq test injections using a 25 guage 5/8 needle.

Pros seems to be
Less or no pip
Easier injection

Cons
Multiple shots vs one weekly.

Anyone doing Subq TRT injections. If so what's your experience and what accessories are you using.

Achak's picture

I use a 25g 5/8" needle and it goes intramuscular. I have relatively low body fat and I'm injecting my delts.

Calitime2020's picture

I have been doing HCG subq injections for over a year and by far the easiest. Using 30 gauge 1/2 inch has almost no noticeable pain, I just inject slowly due to the gauge. I have done a couple of small TRT doses as well, working on the appropriate amount I can do in one injection for TRT, so still researching there. Basically started out small and working up right now seems to be going good. I tend to have a lot more bad injections going into quad or shoulder - pain during and afterwards vs subq I rarely have either. This is probably different person to person but that’s my experience. I have only done glutes, shoulders, quads, and subq. Subq wins for me currently, but still testing after several years for favorite spots. Also on me I have found better areas through trial and error on quads and subq. I also use a couple of sprays that help with pain and are antibacterial before each injection, this helped in all locations I inject.

skinnyTRTdude's picture

I've ran sub q and PIP is kinda dose related. I started 200mg wk test cyp prescribed TRT and the 1/2 mL every 3.5 days left sore spots. Once got a 400mg/mL test and it left very sore spots even with small injections. Back to 200mg/mL test cyp and only 40mg injections left nothing really. Also test was to low at that dose. I've went to IM because after about 2 yrs I'm sick of sore spots. I'm pretty small and skinny and 0.4mL IM injections leaves no PIP. Sub q kinda. Also possible red spots, at least on me.

Dolf's picture

I run all short esters when I cycle, and I use my trt when off cycle as a break from ed pins which is why I use IM for my trt, as well as my cycles because of the amount of gear being pinned ed. I personally like to try and keep my blood levels as steady as possible when I cycle, so subq in small doses ed or eod for trt seems like it could be a good thing as far as keeping more steady blood levels.

DJLowT's picture

If you're worried about the sticks, everybody does, that's completely normal, however, after the first few times it becomes routine. There are a plethora of places you can use, and will eventually find your favorites. I personally never hit my glutes but I utilize both quads and delts with a 23g 1.25" and have been doing so for years (1 12 week cycle of TestE @ 500mg per week once a year) that being said let's get into how AAS injections work.

When you inject an oil based AAS it takes the body longer to absorb the injected material apposed to water based that is absorbed much quicker. Also, the oil based AAS actually has the ingredients suspended and even adds carbon molecules in some compounds along the chain to make the absorption process longer and more uniformly absorbed .

A SubQ injection of an oil based AAS that is made to be absorbed over time is counter intuitive to that particular AAS itself. Muscle tissue has a greater blood supply than the area just under the skin. Muscle tissue can also hold a larger volume of medication than subcutaneous tissue and does not allow leaking through the more porous tissue like SubQ.

As far as the injection site and any pain is concerned, the act of slowly inserting a pin into the SubQ to avoid the muscle vs the more deliberate and faster action taken with a IM injection actually allows more time for the nervous system to react to the foreign object, there is no know benefit to lessoning the discomfort with a SubQ stick vs an IM in my opinion.

Also, everybody here has had to start somewhere, some of these guys can be real pricks and jab at you but it's all part of the comradery, don't let it get to you. Your BEST place to start is research, ask your peers here as well as do your own and you will find the best path for yourself.

To end I would advise to start with a clean diet (which is the hardest part for me during cycles) if you've never worked with diet first you'd be amazed at what a difference it makes. Also, with knowing what your intakes are it's almost impossible to judge what your needs will be on a cycle. It will take about 5-6 weeks before you actually see or feel the results of a Test cycle, but your body will react to it immediately physiologically in ways you will not feel physically. That's five weeks of potential error if you've not began properly.

I would still urge you to do as much research as possible and ask as many questions as possible before you start your own cycle, plan out and share your routine, your intended course of AAS cycles and your PCT. If your not sure what these things are I would encourage you to back up and do more planning.

happy gains!

Greg's picture

I would still urge you to do as much research as possible and ask as many questions as possible

I think you should follow your own advice and bone up on the new info about Sub-Q injections.

DJLowT's picture

I've done moderate research on the subQ, and still believe the IM for carbon added chains are better in the dense striated fiber. I'll keep looking for data. If you have any links I'd appreciate it.

Greg's picture

I've been on TRT for quite some time. My (top rated) endo doc suggested sub-q for many of the reasons mentioned in this thread and others on this website alone. Your 3rd paragraph is (broscience)opinion passed off as fact.

If you do search for sub-q here, you might see posts of mine going back 3 years or so where I too thought IM was the way to go, to sub-q being just as good, to sub-q can be better for more even levels without big spikes.

New info resulting in an evolution of thought.

BTW, "carbon added chains" are called esters.

DJLowT's picture

The total capillary bed of fat-rich tissue is one-third as great as in muscle, that's not bro science that's just a human physiological fact. As the suspended matter is dissolved it enters through the blood stream these capillary walls.

I'm more than willing to look up and research anything you might have handy for the benefits of the sub-q injection of oil based AAS, we're all here to learn. I'm VERY curious about reduction in the spikes, more especially the compounding effect of Enanthate with 4.5 day half life. I'll start combing over your data on sub-q.

Most noobs don't know what and ester is or what differences there are, hell I ran cycles for three years before I knew the difference between enanthate and cypionate, now we've got acetate, propionate, phenylpropionate, isocaproate, caproate, decanoate, and undecanoate.

My primary goal for right now is for the noobs, and hopefully to stop some of the stupid shit I've been seeing over the last two decades.

Ozninjaguy's picture

Snore...been here 5 days and trying to be an expert. You don't know shit about SQ ED TRT. Maybe STFU and listen to the people who do.

Greg's picture

Well, you can start by getting the noobs caught up on the vocabulary, like, "carbon added chains" are called esters.

The total capillary bed of fat-rich tissue is one-third as great as in muscle, that's not bro science that's just a human physiological fact.

Who cares? This sounds like the start of your hypothesis that sub-q must therefore be inferior. So do a study to PROVE your assumption... oh wait, other more learned men than you or I have already started posting results of those studies.

Redmanlfc's picture

Have a read of this study bud, I linked it in my post several posts below but just in case you didn’t see it.

https://academic.oup.com/jes/article/1/8/1095/3988127

mhman's picture

Personally ICan't understand why anyone whoud shoot a oil based compound sub Q, just saying

Ozninjaguy's picture

Obviously you haven't researched SQ ED TRT injections before commenting, just saying.

Greg's picture

Because my doctor told me to...

bdavid21wnec's picture

Can anyone comment on doing subq and DHT/estrogen conversion. Someone further down said the conversion is less. Is this true, especially the DHT.
For instance anyone who sheds on a basic trt dosage say 125-200 per week using IM. Do you notice less shedding when doing subq?

Swolabetic's picture

Recently started the sub q thing as well. For both my TRT and my "added" compounds. EQ, Tren, and or Mast (depending on what I am on). Have done all subq, best thing I have done. Feel great and no more sore spots. Occasionally a red spot/lump which subsides quickly.

BJ's picture

How do you get the oils in an insulin pin?

Swolabetic's picture

You can get different needles. Not slin pins. Like 25guage 3/8 or 1/2 length. Anything smaller like slin pins it's to hard to draw up. 25g works fine. I always warm the gear up as well.

Redmanlfc's picture

Assume you must be using very small doses of eq/tren etc to be going subq with them aswell? Where are you shooting also? Just in the stomach or elsewhere aswell?

Swolabetic's picture

Yes either ed or eod. Small frequency shots.

Redmanlfc's picture

Agreed! I think people have made this subq test dosing more complicated than necessary when it should be simpler and give less ups and downs than regular IM test injections.

For example, have a look at this recent study, granted done on transitioning female to males but should be applicable to men on trt in theory?
https://academic.oup.com/jes/article/1/8/1095/3988127

This states that they get similar levels to IM dosing at a 25% lower dosage and also gives a more stable release. This study used 75mg test c once per week:
“In post hoc analysis, paired comparisons between time points indicated no significant difference among serum total testosterone levels measured 6 hours to 5 days after injection; there was, however, a significant decrease at 7 days, compared both with the initial postinjection measurement (656 ± 244 ng/dL and 477 ± 185 ng/dL, P = 0.012) and the 5-day measurement (621 ± 321 ng/dL and 477 ± 185 ng/dL, P = 0.023). Compared with baseline preinjection values, serum concentrations increased significantly at 6 hours after injection for both total testosterone (497 ± 140 and 656 ± 244, P = 0.02) and free testosterone 118 ± 46 pg/mL and 151 ± 69 pg/mL, P = 0.003). There was no significant difference in serum levels between the two samples drawn 7 days apart immediately prior to testosterone injections for both total testosterone (497 ± 140 and 477 ± 185 ng/dL, P = 0.58) and free testosterone (118 ± 46 and 107 ± 49 pg/mL, P = 0.25).”

So once weekly injection or maybe ideally every 6 days would be fine. I myself use once weekly like a couple of people below. I believe this ED dosing originated from someone on another board who is a bit of a guru and yes more than likely it is better than once weekly BUT for me, arsing about preloading or loading 0.05ml test into 7 syringes each week and then pinning every single god damn day is not my idea of a break!

I, like most people on here I assume do this for a hobbie now and for me the cruise/trt part of the year should be as simple as least time consuming as possible whilst getting health markers sorted as quickly as possible.

Big Ian's picture

I swapped to subq for my self prescribed trt injections a good while back, a few years I would say. Usually backload several weeks at once, 0.5ml (125mg test e or c) each insulin syringe then add 0.15ml hcg (350iu) and inject once a week in two shots 0.325ml was each subq and not had any problems and can’t tell any difference in how I feel from going IM. In theory it should give a more even release with it absorbing slower but can’t say I can tell a difference.

Long-Journey's picture

I've read of many trying to keep injections around 0.5ml per inch, and from my own personal experience this works well. I inject twice a week, and have noticed e2 side effects to be less and benefits to be more consistent in doing so.

The only problems I find are cleaning the injection sites and needle damage from repeated injections. With the former, I've found alcohol swabs to be insufficient for cleaning as there's just not enough alcohol on the pad. As for needles, I use BD 27g 1/2" needles for SubQ injection at an angle, but 3-4 injection sites is the most I can comfortably get out of the needle. After injecting, I've been pressing an alcohol swab or soaked cotton ball at each site and that has kept lumps and redness down, like I've read.

No abscesses or significant problems if I take my time and make sure everything is clean, but it's definitely more involved than IM and I have screwed up before when rushing.

Ozninjaguy's picture

You don't use a 25G needle - you use a 30G slin needle. Been doing SQ ED TRT for around a year now (maybe less - can't remember).

Pros: No pip. Can hardly feel the needle. No lumpy masses in your muscles from injecting. Even and continuous supply of Test - closely mimics natural Test creation. No highs and lows as a result of big exogenous Test levels in the system. No Estrogen/DHT reaction/conversion because of the excess Test in the system.

Cons: Have to do it every day - just like waking up, going to work or having a shit. Can sometimes develop a small lump or bruise if you inject into a blood vessel (goes away in a few days). You use a lot of slin needles. Because you are injecting daily it's easy to forget a day - if you are using Test E or Test C - no problems - you can go 2-3 days without shooting due to their slow release - it's not ideal, but just make sure you are still on track with your weekly dose. Other cons? None.

Want to find out what it's like? Try it.

BJ's picture

I do want to find out; you convinced me! Gonna go for it this way. Thanks

Ozninjaguy's picture

Post up blood work before you start and after around 6 weeks so you can see the effect and if your dosage is correct. I have posted up lab results for both 50ml PW (after about 6 weeks), and 80ml PW (after about a year). I am using Test E. The dosages were divided into daily SQ shots. I originally started with almost zero natural Test in my body (I think I also posted up that blood work), so for me, the results are impressive, the more so since my E was way over the top in the beginning, and by last lab work it was dead centre of the normal range.

ashop's picture

SubQ injects are very popular these days. I did them for awhile. I got tired of doing them daily and often got very busy and just forgot to do them.

Ozninjaguy's picture

Use the search function. This topic has been discussed ad infinitum ad naseaum,

I have been running SQ ever since being put on TRT and prefer it over IM injections.

The point of SQ is to divide up your TRT into DAILY shots and do them SQ....you DON'T shoot a ML or more of Test SQ. That's just wrong. SQ injections are about avoiding muscle damage through using large gauge needles deep into muscle tissue.

Ozninjaguy's picture

Thanks for the reply. I know that you are not arguing - just to clarify

That's very interesting. And even more interesting is from what's been said below, that these sub-q injections can only be done with pharma grade testosterone, and not just any UGL test. Well, that's if you don't wanna have burning pain, redness or whatever, lol.

Whoever is saying SQ can only be done using Pharma grade is talking shit. I live in the Philippines and the only injectable Test here is Undecanoate. - too expensive and I'm not interested in the possible roller coaster of high/low serum levels over the 10-12 weeks between shots. So, while my Endo prescribed Test E for TRT - it's not available. I'm using UGL and have done so for the last year and stand by everything that I have said about SQ injections. No burning pain and the other bullshit. Send me a PM if you want to know what I'm using - I bought it here through an Eroids source and my blood work has proven it to be legitimate.

But if someone is only injecting 0.5ml (100mg) of test, with a 25g pin I.M. once per week for trt, as I do when on just trt, is muscle damage really that big of a concern?

Probably not a big concern, but I favour SQ because of how it mimics natural Test release. Your body produces about 7 -10mg of Test a day when you are young and fit (which makes me think that guys of 200+mg a week for 'TRT' are full of shit) - injecting 100mg on one day has an impact upon your hormonal balance. Even if it's slow release like E or C, it's still much more than your body would produce on a daily level, thus your body reacts to the extra Test in your system by shutting down any natural production, and converting it to Estrogen and DHT. Hey mate, it's your body - make your own decisions.

Greg's picture

Whoever is saying SQ can only be done using Pharma grade is talking shit.

He's misquoting once again. I don't recommend UGL because of the possibility of redness and a stinging pain that I've experienced when using only two UGL labs v my scripted test. And, at a dose closer to 1cc.

Smaller micro doses of UGL product, or other UGL labs I have not tried; may be completely ok.

BJ's picture

Good to know! I'll make sure to use pharma grade when I start subQ TRT. Thanks for that experience info.

Ozninjaguy's picture

Fair enough mate. I use Test E 250mg/ml and at 80mg PW divided up into seven shots - my SQ shots are minuscule. As I have commented before -- sometimes I hit a small blood vessel and being on blood thinners it will cause a lump because of build up of blood -but it goes away in a few days.

Personally, I wouldn't be pinning close to a ML SQ - if it's a water based injection, that might be ok, but a ML seems like a lot of oil just under the skin. Do you do SQ to avoid muscle scarring/pain, or just to try something different?

So far I'm happy with the UGL gear that I (have no choice to) use, but TBH I would have been happier if Pharma was available, simply for the quality of manufacture and the fact that the dose on the label is correct. I have no idea if my UGL is overdosed/underdosed and it was all pretty much guesswork trying to figure out my PD shot. So when in the future I use a different brand/or same brand different source - I have to go through the whole blood work thing again as I adjust the dose to fit the strength of the gear, if you get what I mean.

Greg's picture

How can this be?? I'm not afraid to admit when idk the answer to something, and this happens to be one of those areas. So what are the pros to sub-q test injections compared to I.M. test injections??

Try reading the replies below... pharma = refined and controlled processing. UGL= who knows.

Greg's picture

I don't know for sure why, I've suspected all you've mentioned. I do know I have tried both. It was new to me to have a new endo doc prescribe subQ. I was sceptical but tried it. It was easy, no PIP, no redness, only a small welt that disappeared within the hour.

I thought cool, now I have more rotation sites. Wrong. I tried twice with UGL products, different labs. Each had a degree of stinging pain, welt and redness. (one product was much worse than the other) Pain went away in about an hour as did the welt but the redness lingered for about a day or two.

I have not tried with "all the gear", so I can not make a claim, "...not any other gear". Hence, my statement I would not recommend UGL gear. I also would not recommend more than 1cc irrespective of pharma or UGL. It started to feel very uncomfortable injecting more than 1cc of pharma when I tried once. Maybe a mental thing but I felt "queasy" enough to want to stop at 1cc.

Greg's picture

It was Doctor prescribed Wa*son

Dr.BroScience's picture

Injecting oil sub-Q is never advisable. The assumption of less or no pip is false. In fact Sub-Q oil tends inflame the surrounding much much more than intra-muscular. You risk infection & the dreaded abscess. No need to reinvent the wheel in regards to TRT.

Thank you for the post. Hopefully this thread will help clear up some of the misconceptions floating around about sub-Q oil injection.

MegaT883's picture

Done it before. Totally disagree. List is long of TRT Dr's nation wide who recommend subQ injections. Pharma industry and FDA disagrees as there are now subcutaneous testosterone enanthate auto-injectors. SubQ injections is something that has been studied by the medical community for awhile now.
What giardap and Greg have stated is fact not BroScience. (but I wouldn't inject 1cc of 400mg Test subQ ouch! lol)

https://www.ncbi.nlm.nih.gov/pubmed/30296416

https://www.ncbi.nlm.nih.gov/pubmed/17143361

https://www.ncbi.nlm.nih.gov/pubmed/29293461

Greg's picture

The way my doc described it is, that the drug companies only tested IM injections. Tests/studies that go before the FDA are lengthy and expensive. Drug companies have no incentive to go through the process to get SubQ approved by the FDA.

Same issue with clomed therapy for men. Unless someone is willing to go through the FDA approval process it will continue to be prescribed outside of the drugs intended use, and never covered under an insurance policy.

MegaT883's picture

In Nov. 2018 Antares Pharma Inc announced the availability of XYOSTED which is the only FDA approved subcutaneous testosterone product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable QuickShot auto injector. XYOSTED was approved by the U.S. Food and Drug Administration (“FDA”) on September 28, 2018.

https://www.globenewswire.com/news-release/2018/11/29/1658821/0/en/Antar...

https://www.xyosted.com/

Greg's picture

That's great. But no one is going back to get re-approved for subQ for a drug that already has been approved for IM. Perhaps if they start losing market share to XYOSTED...

giardap's picture

That's test prop talk, and/or injecting wrongly into fat
What you describe doesn't happen when done correctly