Can taking medrol dose pack cause insanely high PIP??
So about a week or so ago, I had to have an emergency root canal due to tooth pain. Everything seemed fine, but once I started taking the prescribed medrol dose pack, which I believe is an oral steroid of sorts, I’ve had very painful PIP. It’s almost like the muscle is hugely sore and tense, or maybe has a knot. I’m 5 weeks into my first cycle, the first 4 weeks, nothing beyond a little soreness for a day or so, but not like this. The only difference is that I was given the medrol dose pack to take. I just finished the final one, so I guess we will see if it subsides, but I just thought I’d ask you guys, if that seems plausible… Is it somehow fighting the foreign substance or something?
Thanks for any help. I’m only taking 600 mg Test E a week, split into two injections.
The actual full medication name is:
MethylPREDNISolone Tablets
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Ive been on oral prednisone when on cycle and I can assert this phenomenon is real. I dont know the mechanism but the same shots that are no PIP for me feel like Im kicked by a mule if im on oral corticosteroids.
So I have an update. Everything seems normal. I can't explain it. Literally the only thing different is I've been off the meds I described earlier for a week now. I know everyone says they would have no effect, but I have no idea what the cause was. I've injected a delt and a glute since, and no pain again, just the normal slight soreness for a day or so. So, either way I'm happy, but it drives me crazy not knowing. Anyways, I just wanted to update everyone, as I know people are prone to never come back and update a thread. Thanks for all the info and suggestions from everyone.
Well, I guess we shall see how I feel in the morning. I just did my other delt. I did heat up the oil with a heated rice pack like your forum post suggest. If this still hurts, I’m gonna try swapping to the other brand I have and go from there.
Let me ask this. Would injecting to fast cause the pain or issues I’m describing? I don’t think I did, but at this point, I’m second guessing everything I did last week.
Injecting fast won't have that effect. I would get your WBC checked to see if you have elevated levels which would suggest some type of infection or allergic response
2nd question, because I simply don’t know, how do we know increased WBC is from this, verses the infection I had that caused the root canal, etc. thanks.
Probably can't distinguish between the two. If you are finished with mpred then I would assume that issue is cleared up. If continued high WBC then you may be having an allergic reaction to the gear. Just throwing shit at the wall and hoping something sticks here for the most part though.
I understand. I'm mainly asking questions, because I genuinely don't know and want to learn. I appreciate everyone even taking the time to respond with any thoughts at all. So far the warmed, and super slow, hurts exponentially less than the other spots. I just really don't know what would have been so different all of a sudden. Now, I am still learning to warm the vial properly, so no telling if I did that right, and probably errored on the side of not warm enough as I was afraid of damaging the compound from what I was reading. But baby steps I suppose.
Wrap the vial in a heating pad on high for 10-15 minutes and then draw and pin. You are not going to damage the compound at all.
Ohh, I definitely didn't heat it up long enough. However, I have those rice thing heating packs, so I'm not sure they stay warm that long. But, I will say, so far my delt I pinned this morning is still going good. Just the normal feeling, not the super extreme stuff I've been describing. The only different was semi heating, and injected very slowly. But I have full range, no extreme pain, etc. I feel like that probably means I'm not allergic. This whole thing has been super weird. My glutes returned to normal, not hurting anymore, probably 5-7 days or so. My right delt still feels uber sensitive and certain touches, movements are painful, but nothing that is debilitating. Thanks again for all the input, especially the long time members. I do appreciate it.
Ahh ok, I did blood work Monday, so I should get reports back in about 7-8 more days. So, after waking up, I feel a lottle soreness in this morning injection site, but nowhere near the levels of the other delt or my two glutes. I did hear it up, not sure I heated it up enough, but I tried, and I went methodically slow.. I’m going to give it a day or two to see if the pain increases or subsides. To the next test
lol
I did read another thread that I think helps me put into words what I’m feeling. It’s like within 24 hours of pinning, it’s like the pain of building a new muscle. Like the first time I ever went to the gym and couldn’t move because the muscles were just completely tore down and I went way to hard. Now, could it be a combination that my strength has gone up exponentially in the last few weeks, and I am hitting so much harder and heavy and way more reps/sets overall. At first that’s what I was attributing the pain to, but it’s just so odd that after pinning, it feels fine, the normal after pinning feel, nothing at all, but the next day when I wake up, it’s like brand new muscle was made over night.
MPred should actually help with any pain/inflammation, so you have something else going on.
Tge only thing to draw your attention to to prednisone does put you in a position where you’re more susceptible to infection. No redness / swelling etc around injection points?
no redness, swelling, nothing. Just pain, like day 2 of really hard leg day after not doing legs for a year or two. If that makes since. Also, on my delt, my range of motion is impacted by the pain. On the glutes, I can move, it just hurts when the muscle touches something, like example up above.
Its wierd for me i can make it to the next week and forget what side i even injected on, right or left. Sometimes it with walnut size lump up and hurt for a week, or sometimes extreme pain right after injection and go away 2 days later. I do everything the same each time but just never know the end result. Completely random and not controllable at all for me.
DamikePrednisone is a strong anti-inflammatory and reduces allergies. If anything it would help reduce pain after Injection.
When I have had root canals they never give me any meds afterwards, only thing I have ever had from a dentist is Amoxicillin antibiotic. Oh yeah and the other fun ones - Lidocaine and Propofol LOL But they wouldn't let me take the vials from those!
Methylprednisolone and Pip are almost certainly unrelated.
Rustyhooker4pin points minimum or....??
18ga?
Mainline?
Rusty spear?
Yeah I usually do both delts one week, and both sides of the glutes the next. 25G x 1” for the delts, and 23G x 1.5 for the glutes.bonuses two needles each injection, one to draw the vial, and then a new one to inject. I wipe the tops down with fresh alcohol wipes before drawing up. I clean the injection area with another new wipe. I always aspirate, the best of my ability, and that’s that.
I guess I just assumed that if I was doing something wrong, it would have happened from the get go, as I don’t feel I’ve changed what I’m doing at all. Obviously I’m still getting used to one handing this stuff, but just assumed that’s what caused the slight discomfort before. This with the whole muscle hurting just feels different, enough so that I felt compelled to ask about it as it simply feels wrong. Maybe I should simply cut this cycle early at 5 weeks, wait a couple weeks and do a short pct, and give it a month or so and then see if it goes away. Idk.
RustyhookerClick my avatar.....warming your gear. Try that forum. Heat pad on pin spot if needed and see if theres a difference. 4 spots with 300 is typically easy byt learning your body reactions takes a minute. The barrel of pin warn...just like baby bottle...touch your lip. Comfy warm...not hot...
I get that and I will try it, but if I’m hypothetically doing everything the same as I have been, what could possibly change in week 4 to cause this in every site? I could understand maybe one bad poke, or rushing, etc, but the last 3 now? It just seems so odd to me to start happening after 4 consecutive weeks of zero issues. Anywho, I’ll try heating it up and see if that helps on my next delt on Wednesday.
A little more bro as I try to figure how to put it into words. It’s almost as if the muscle I’m injecting is staying in a constant flexing position, but I’m not flexing. Idk how else to describe it. Like it’s not spasming, but the muscle does feel rock hard, even at rest. My 9 year old noticed how my right delt looked much bigger. I’ve felt around and it doesn’t fill like the liquid is sitting there or puss or anything, it’s just super weird and painful. Hopefully this helps explain a little more and I don’t sound like a complete jackass idiot. I am trying to learn and do things right here. Anyways, thanks for those that replied, I’m just trying to figure this all out.
RustyhookerNew to it. Try warming....if not then maybe its judt not for you. Noone wants to hear that but stabbing ourselfs with a needle isnt really normal. Its funky weird and can hurt.
I get it. Maybe, we shall see.
What type of oil is your Test in? I have an allergy to grapeseed oil and causes me to get inflamed. Took me about 7 weeks to figure out grapeseed wasn't for me. I would get large knots and it would be sore for up to a week. When I switched to something else all the problems went away. Just a thought.
I’m not sure, I’ll have to ask the source and see if they can let me know. Would that cause an issue over time? Like it was the same bowl for the first 4 weeks without issue, then just all of a sudden, BAM… sorry if I sound redundant, this is just really catching me off guard.
All good man. It can take several weeks for symptoms to show. I've tried it on several occasions and grapeseed oil for me just always causes issues for me. MCT causes some people the same issue. It can vary person to person. For me MCT is perfect. Also how fast your muscle absorbs the oil. Castor oil absorbs really slow, up to 30 days. Grapeseed can take up to a week and MCT a few hours. Just something to think about.
The oil is MCT.
Only way to know for sure is try another carrier oil. Some people are allergic to MCT.
Thanks. I hadn’t even thought of that. I did reach out to the source and I’m waiting for a reply. I do have a vial from a second source, because I pre bought a bunch as I didn’t want to keep going back every time. So maybe I’ll crack one of the 2nd sources open and try it.
Thanks guys. It’s just weird. Everything was fine the first 4 weeks, and now, each injection is causing this, regardless of the spot. I’m injecting at the same pace as before, and even hit a different vial to try and rule out something happening to the 1st vial (I was at the end anyways). Idk, first it started with my flute points, but then yeaterday with my delt, now the same feeling, it just feels so out of place to the first 4 weeks.
I know I’m new, but it’s such a stark change and I can tell something is behaving differently. So, it’s just odd. I did just go get my 4 week blood work done today, so in 10 days, I’ll be able to see if that all looks normal.
I’m trying to decide if I should stop for now, and wait for it to subside. It’s like the whole muscle is tense and sore from a super hard leg day, you know where it hurts so much, sitting and standing hurts to touch the muscle when you have to move. It’s like that. But today on my right delt, I felt it hurt, but n that same way and I never feel that. Weight wise, I was fine, but the stiff soreness was causing an issue with dumbbell military presses, due to range of motion. Idk, this is seriously throwing me off right now and I’m not sure what to do. I wish this was a known thing with that drug interaction, as that would at least explain things, but now back to mystery and that sucks.
Thanks anyways guys for the insight y’all had. If thoughts or suggestions, I’m more than open to hearing you out.
I've had a few root canals and have never been given a medrol pack. It's always antibiotics and vicodin. But the medrol shouldn't be causing any pip. It's an anti inflammatory cortico steroid. More likely it's your first cycle only 4 weeks in could've hit just a sensitive spot or shot the oil in too fast. Anything can happen. I've had to take prednisone on cycle and have never had an issue.
When I get home, I’ll look up the full formal name of the medication they gave for those unfamiliar with the common name.
DamikeNo