+ 4 Case studies "group"
Hey Guys,
Was wondering if you think a group was formed called "Case studies AAS" that it would help some eroid members. Wanted to hear some input from everyone on here if you think it's a good idea. Now many people do post links of case studies and academic literature on AAS, but there's also a lot of broscience on here. Should we create a group or topic called "case studies" where people could find an upload just case studies of facts & true life stories. Not to put down any personal hearsay or trial and error. They have their place too, but something more scientific. For example, here's a case study I found about a 26 year old using a gram a test that landed in the hospital after 5 weeks. Maybe if this person or other people read this it'll prevent them from using a gram of test and having the same story. What are your thoughts guys and gals?
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Manateeswimmer5678For everyone debating the tren brain damage effect just remember in those studies that the damage was prevalent in individuals not running a test base or using an addition of DHT. The reasoning for this effect was because no test base means no aromatization meaning no estradiol for the neuroprotective effects estrogen provides. Alpha beta plaques also are allowed to form more freely and these are the same neurotic plaques causing Alzheimer's. There is a very simple and efficient way to fight this, get good deep sleep. When we sleep our microglia clean up our brain by clearly the debris and preventing the formation of these plaques. Remember, estrogen is our friend .
Read this study out of Norway! 89 athletes and weightlifters AAS & a 70 natural athletes/weightlifters
https://www.sciencedirect.com/science/article/pii/S000632231632529X
I drink high Silica H20 to combat plaque build up in the brain. "Get Good Sleep" huh what? While running Tren? Might as well tell me to dunk like Michael Jordan! Not trying to be rude.... it's just nearly impossible for me to deeply sleep 8/9 hours straight on TREN. Only ran it twice in my life(Thank God)! Ask 10 people running Tren if they had a good night sleep last night.
Manateeswimmer5678Lol im saying the most important thing is to have estradiol present in your body, the second thing we can do that is super effective is sleep and rest.
I sleep brilliantly on tren, always have done. I can also nap much more on it too. The problem is if any is the extra hunger it causes me, that's what wakes me up. The compound itself actually makes me feel sedated and relaxed.
I've heard a few people say that! I just watched a YouTube Interview recently with Bostin Loyd and he says he's super relaxed on Tren. That's actually awesome and has that effect on you. I would love to know the exact science on how it affects different people like that. Makes many people nutjobs. Lol
On top of the 10 + PED's Bostin Loyd runs I am sure is on benzos and/or psych drugs. Bostin has claimed he is OCD and has bad anxiety. So sure he takes something for that which helps him sleep through anything.
Funny I never had any sides with Tren e but Tren a is like a complete different compound to me.
Find tren a to be much stronger and get sides with it. When the insomnia gets to bad I have to come off.
Terrible advice.
If thats your explanation, you haven't read all of the studies. Smh.
Manateeswimmer5678Deep sleep is helpful only after considering the individual has estrogen available for the neuroprotective effects. Im not sure how or what I said was wrong, I was commenting on the study about Alzheimer and tren
You are full shit, you liar. There were no 'individuals' in the alz/tren/plaque study. They used wistars.
Further, estrogen in no way inhibits tren causing plaque production, particularly given its rapid onset, its binding affinity, and the fact that estrogen receptors also mediate the effects.
And again, estrogen was absolutely present in the wistars. Nothing you said related to it.
You didn't read the study. Liar.
I agree with you this time mate.
Way way more in depth than what hes stating.
Sometimes people get fixated on one part of their particular research that they skip or avoid the possible 20 other function leading up to something etc...
Thats google research.
Can find an answer supporting or negating anything.
You can literally get a yes or no for everything.
I can see where he was trying to head but yes i agree with you.
I shouldn't have given him so much shit.
Yeah completely agree with you. Not to mention the amount of studies carried out by bought and paid for wankers who try to fool us all.
Wouldn't mind, but I love tren. Wonder drug.
Manateeswimmer5678And this is in regards to sleep comment.
https://www.nih.gov/news-events/nih-research-matters/sleep-deprivation-i...
Still not sure why you're so adamant on me being a liar when the statements I'm making are from studies man. Im just contributing what I can. And of course they can't use humans in a study that involves injecting various amounts of hormones. Yes they used animal models but the study clearly is trying to correlate a point that estradiol is important in neuroprotection.
Well it is simple really, by citing irrelevant studies, you are making things up, and making assertions based on abstracts and references to studies you clearly either haven't read or dont understand. You are essentially making things up.
What you are doing is the opposite of the purpose of having a case studies group, whether you mean it or not.
Manateeswimmer5678Not sure where your anger or aggression is coming from but estrogen does prevent alpha beta plaques
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585711/
"Thus, estrogen exerts downward pressure on Abeta in about 10 different ways in the model, and so the dramatic upraising of Abeta in the absence of estrogen is not surprising."
The study that tests the injection difference for dht and tren vs tren vs test combination etc clearly show the trend that estrogen is neuroprotective as well. No need to get upset and accuse people of being liars man.
Ok fair enough re: aggression, fair enough, point taken.
Regarding estrogen, you are jumping context to make a point.
So, let me be clear on what I am saying here. In the context of normal people, with normal levels of estrogen, or rats rather per the study, estrogen has NOT prevented amyloid plaque buildup.
Whereas what you are saying is this: estrogen is neuro protective and a target for alz disease research given the prevalence of alz in hypoestrogenic people. This is valid and true but unrelated to the datavin the case of supraphys doses of tren.
So, you used an unrelated truism to support an opinion without regard for the (nearly; only) data we have that shows in eu-estrogenic rats that 1. Plaque builds up after 1 dose, and 2, it seems to also be mediated by the estrogen receptors as well as.. etc.
:0)
I like this one w/ almost 150 people out of Norway w/ MRi's.
https://www.sciencedirect.com/science/article/pii/S000632231632529X
Excellent stuff Mate ++
Manateeswimmer5678thanks good sir!
Manateeswimmer5678+1 from me for a great idea. Definitely will be paying attention to this.
Great idea. It could work if the study was presented back. I.e. a proper read, not an abstract surf, and a present back or discussion of... +s for smart approach
I think a basic teachback, is the key to making it worthwhile...
This dude is king for this ^^^^^ both of you should do it together.
Hows it going Flash?! Hope your well man?
I hear the Aussies are making some moves to ease restrictions a bit??
Howdy mate, im good you?
Yeah moving forward but im in a state that is still strict.
Ill bare with it.
I just want the gym to open but they keep changing it.
Good to speak again.
See ya round mate
All good here mate, going a bit stir crazy now. Running out of things to cut down with the chainsaw or paint!!
Tell me bud - back in your Adrol days did you find a big difference between taking 1 tabs to 3 tabs per day?
3 tabs is the best way mate.
1 every 8 hours.
Stability and half life is key.
For even better results you can split the tabs in half and take every 4 hours.
Cheers mate
https://jasn.asnjournals.org/content/21/1/163.long
This one is scary!!!
Cplvela0811To be fair, regarding AAS and brain damage, it can cause hypertension, which in turn can do detriment to the cephalic blood vessels. That high intravenous/arterial pressure beats your brain. Think of micro punches - constantly hitting the brain. It also adds to dementia related problems. My only dilemma being how much (damage)) though, is the question.
Tren happens to be a personal favorite of mine, right next to some authentic Oxandrolone.
So that’s what’s wrong with me
One thing of many Bulkdaddy
Molinin302I'm for it, proven science can't hurt. +1
As long as it stays in it's realm and people don't start posting penis enlargement links lol
Sending dick pics can be an impulsive behavior! This AAS Case study touches on that to some degree.
https://www.ncbi.nlm.nih.gov/pubmed/24841181
Cplvela0811It couldn't hurt. Might even get people to present their findings. The only thing that I can see becoming an issue, is source citations. Not all studies are created equal. The more reputable the source, the more likely it would benefit the cause. PubMed is very reputable.
+1.
Like these two scientific papers about Tren & brain damage! Scary stuff
https://www.ncbi.nlm.nih.gov/m/pubmed/25461682/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458166/
Hard to take brain take brain tissue to study, from aas users when they are alive so this is mostly what we have wrt tren. :-)
This said there are several good studies across a range of aas including test and nandrolone, that show neurotoxicity.
The problem with forums is most people dont really read the studies, but abstracts at best. And most do nt come on here to widen their view or have their minds changed. You could have all the evidence in the world, stack it beside the thousands of eroid user reports of cognitive impairment, and people will still think its bullshit!!! LoL
The old "It can't happen to me way of thinking". The users in the golden era & 80's didn't use the doses today's users are running. Soo the millions of users today most definately are gonna see different results when into their older years.
Not this rubbish again lol
If any of it were true then there would be 1000's of Brain damaged bodybuilders walking around the streets by now. Tren's been around for decades, wasn't this all speculation based on a rat's experience?
Figure 3 in this study has human brain scans!
Good read anyway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458166/
Gym rats! :@)
I'm all for scientific research, however that alleged 'scientific research' lumped all AAS into the one basket.
Their results did not differentiate between the effects of different AAS, and as we all know, all AAS do not have the same physiological or psychological effects, thus this research is seriously flawed, through assumptions and poor design.
That's like saying all NSAIDS and Antibiotics are the same, and have the same effect.
Basically - it's rubbish.
https://jasn.asnjournals.org/content/21/1/163.long
What do you think about this one? Anabolic Doc referenced this one today in his new video! Scary stuff...
It a well done piece of research but only one case study - even though they had a cohort of 10. Their conclusion that the renal damage was caused by AAS, (in the index's case - Testosterone), is not conclusive. They did not eliminate other variables such as the very high protein, creatine, aminos and supplements.
1g PW of T is pretty high and also 550g/pd of protein is well over the top. High Protein on its own has negative effects on kidney function. https://www.ncbi.nlm.nih.gov/pubmed/27801685
Also, Creatine causes kidney problems - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421632/
Having said that, I have no doubts that excess dosages of all AAS have negative health impacts - that's why I always ran low dose cycles.
Thanks for the read. +2
Cplvela0811Someone has been putting in work. Excellent find. +1.