CRAZY DOSER's picture
CRAZY DOSER
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+ 1 MUST READ ! HGH and GLUCOSE LEVEL

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I noticed that most of my customers are concerned about the various quality aspects of GR, the method of use, dosage and supplier selection. No doubt, all these factors are important. However, more important is the question of potentially dangerous side effects that can occur with regular use of GR. One of the most dangerous side effects - is stress for the pancreas with the suppression of its functions for the regulation of glucose blood levels.

How you can check if taking GR is dangerous for you?

It’s definitely an objective evaluation on the state of the pancreas for the subject of different pathologies, which are determined by the methods of sonogram (ultra-sound examination) and MRI (magnetic resonance therapy). The result of these studies will be a medical report on the presence absence of tumors and pathological changes in the structure of the gland.
The main point that we shall examine: evaluation on the effectiveness of the pancreas on blood glucose
regulation.

You definitely need to consider several key indicators :

First is The level of glucose in blood.
Second is the level of glycated hemoglobin.
Third is the result of glucose tolerance test.

1st indicator “The level of glucose in blood”. The analysis is made in the morning on an empty stomach, without excessive fluid take prior. The excess of the reference value should at least show you the need to check this value once again or several times to find out how stable your glucose level goes beyond the upper limit. If this is the result, it is necessary to make a second analysis on the level of glycated hemoglobin.

2nd indicator “The level of glycated hemoglobin”. The analysis is made in the morning on an empty stomach, without excessive fluid take prior. The stable excess of a second indicator is a very alarming symptom !

You are in a zone of additional risk, because the combination of increased values of indicators 1 and 2 shows that you are likely to have the following problems : insulin resistance, pre-diabetes, diabetes type 2 non-insulin dependent diabetes or type 1 insulin-dependent.

If your test results on 1-st and-2-nd indicators show sustained excess, it makes sense to make a glucose tolerance test. This is a simple procedure, but it takes time. The point is, it allows you to determine the effectiveness of the functioning of your pancreas in dynamic, rather than single analysis at one moment. At the end of the test, you can get the glucose utilization time ( taken preoral at the beginning of the test), which will show how well your body works with the carbohydrate component of the diet.

Let's suppose, that one of the test shows excess. What should you do in such situation?

First steps for the relief of the situation:

active exercise to reduce body fat % (bodyfat)
depleted carbohydrate diet and a complete rejection of the "fast" carbohydrates
daily monitoring of glucose levels by using portatble glucometer to understand the dynamics of change in your personal glucose level depending on your diet and stress

start to use of METFORMIN (SIOFOR-850 or SIOFOR-1000) with 1700 - 2000 mg dialy for the fast disposal of excess glucose and increase of tissue sensitivity to its assimilation.

Important ! DON'T USE on your own such medicine as SULFONYLUREAS and INSULIN medicine without prior medical consultations. it can cause irreparable damage to you and make you disabled, or get you into a comatose state. Don’t experiment with such dangerous medicine if you don’t have experience with taking insulin and hypoglycemia edema.

To sum up:

Make tests for glucose and glycated hemoglobin.
Also, it is preferable to make glucose tolerance test.
daily monitoring of glucose level (until meal, 2 hours after meals,before and after training) by personal glucose meter.
The use of , if necessary, METFORMIN 1700 - 2000 mg twice a day in equal portions during or after a meal.

Excuse me for such short summary on these serious and difficult questions, but this subject is to big for one article.

I certainly hope, that my “first aid” package on these questions will be useful for someone. And, of course, you need to get professional advice from a physician-endocrinologist.

CRAZY DOSER.

Makwa's picture

So to sum things up here, it sounds like GH decreases your insulin sensitivity and metformin use will help reset insulin sensitivity. So monitor glucose and if levels are elevated (ie pre-diabetic levels or higher) then use the metformin. Am I on the right track here?

CRAZY DOSER's picture

When using exogenous HGH you get into a state of hyperglycemia (excessive blood glucose levels). In response, the beta cells of the pancreas start to secrete insulin. In short it looks like this: the injection of HGH - hyperglycemia - the secretion of insulin in response - normalization of glucose level.

The main properties of metformin:

  1. Metformin inhibits gluconeogenesis in liver
  2. Reduces the absorption of glucose from the intestine
  3. Enhances glucose utilization in tissues
  4. Improves tissue sensitivity to insulin

As you can see, metformin allows to achieve several goals at the same time:

  • To reduce the harmful effects of hyperglycemia, i.e. reduce the intensity of glucose production in the liver, and reduce the level of glucose that is taken from the food
  • To increase the tissues sensitivity to insulin

    All this makes it possible to "unload" your pancreas, allowing it to secrete less insulin to normalize blood glucose levels after meals, and the injection of exogenous HGH.

I think you are on the right track.

However, keep in mind that monitoring glucose level should be done not only on an empty stomach but also in those moments when the effect of your injected HGH completely ended. It is important ! Otherwise, you’ll get consistently elevated results of glucose tests.

Also, I think that you shouldn’ t "demonize" metformin and make some absurd scary stories ... It’s only necessary to properly apply the drug and understand its purposes. In practice, metformin has no effect on insulin secretion of pancreatic beta-cells and doesn’t cause hypoglycemic reactions.

Makwa's picture

Not sure I demonized metformin here but I have used it fairly regularly before, mostly during cutting, but I am now going to be incorporating HGH in my regime now which is something new for me so I am trying my best on how to now utilize metformin with this HGH run. IGF1-LR3 is also going to be in the mix.

CRAZY DOSER's picture

Excuse me... I told about another person, not yours, of course.

joshDC's picture

OK, so I have a question on this. Naturally, my fasting glucose runs about 95. On HGH things are significantly different. If I eat frequently, everything behaves normally. If I fast, especially if I exercise while fasting, glucose is high, 135. This was the case over an entire 2.5 day fast recently. I did not feel hungry at all in fact. Once I resumed food intake, everything was normal (90 ish fasting.. 125 after eating). Should I be taking metformin to shuttle the glucose when my sugar is high, paradoxically, from not eating or just leave it alone? Would that accelerate fat loss or...?

CRAZY DOSER's picture

You have a normal response to the GH. Upon injection of exogenous growth hormone your blood glucose level should be increased adequately to GH dosage. This, in turn, stimulates the secretion of insulin (as the body strives for homeostasis, for balance). Enhanced secretion of insulin designed to lower blood glucose levels and counteracts the strengthening of hyperglycemia. This is the mechanism of interaction of the two hormones detrimental effect on the pancreas, depleting it. In my article I warned GH users about this.

As for your question ... thank you for the information. I think you need to clarify two main options:
1. whether your dynamic change in blood glucose levels is typical (time of glucose levels drop after meals). Glucose tolerance test or a statistic based on monitoring glucose levels throughout the day.
2. Based on your goals - whether you are in a state of mild or moderate ketosis. i.e. increased blood level ketones or urine. If the excess is and it is stable, then you are really burning fat.

So I wouldn’t use metformin if your indicators are normal on these two options. In fact, you should be worry about abnormal body reactions to the injections of exogenous hormones (in your case, GH and Insulin), as well as stable abnormalities in blood tests. The combination of these factors should alert you and prompt you to clarify the cause as soon as possible.

For more accurate determination of the ketones level in the urine, you can use a special test-strips, they are quite cheap and easy to use. For more precise quantification of ketones, you can use the test-strips to determine the level of ketones in blood and the appropriate portable glucometer with a function of measuring ketones.

CRAZY DOSER's picture

What type of your diet and type of cycle (bulk or cut) now ?

joshDC's picture

I'm taking the HGH to heal an injury so I can get back in the gym. Caloric intake is maintenance, but I gained ~10lb in the first month while getting leaner (practically no exercise, just rehab/pushups, walking). Diet patterns I mix up in terms of timing. Content is basically 30/30/30 except that one of my snacks is a MetRx bar. On timing, I either do 3 meals with an 18hr fasting period or I do 5 more modest meals spread out like a normal person. I will do a full fast one day every other week and every so often I go for two. I mix up the eating pattern every few weeks. My blood sugar does not normally rise when fasting extended periods regardless of meal patterns, but it does with absolute consistency on HGH. I can get to work, measure 90, eat nothing and 4 hours later and after walking an hour pull 135 like clockwork. I'm taking 4iu now, but I first noticed this on 3iu taking 1@6:00am, 1@11:00am, and one at 6pm. What relly blew me away was that before thanksgiving I decided to fast from Monday evening until turkey on thursday save a few pecans while making pies. My glucose was 130+ the whole time. Once I ate a ton, it was back to 90 a few hours later.

MedDx's picture

I certainly hope, that my “first aid” package on these questions will be useful for someone. And, of course, you need to get professional advice from a physician-endocrinologist.

First aid...really? Lol....

Last sentence says it best.... Smile

CRAZY DOSER's picture

I read our correspondence once again. I am very regret that such serious topic causes a sarcasm and intention of confrontation...

MedDx's picture

The use of , if necessary, METFORMIN 1700 - 2000 mg twice a day in equal portions during or after a meal.

Metformin 500mg p.o. b.i.d. is more of an appropriate dose and regimen. I would never advise anyone to use this much of an oral hypoglycemic agent.

Is this what the PDR recommends? I didn't think so! What scientific medical research journal says it's okay to use Metformin in this way....?

CRAZY DOSER's picture

Use 2 x 500mg and check result (for body weight 80-100 kg)... After that use 2 x 850 mg or 2 x 1000 mg and compare this. For additional info read about ED dose for METFORMIN and try to understand than it differs METFORMIN from hypoglycemic agent...

MedDx's picture

Okay. This will help clarify when others read it. Metformin should be used by advanced, and experienced, professionals only!

And, it helps stimulate the Islets of Langerhans of the beta cells in the pancreas to produce insulin. I know what the drug does and it's a hypoglycemic drug because it lowers the blood sugar.

CRAZY DOSER's picture

"And, it helps stimulate the Islets of Langerhans of the beta cells in the pancreas to produce insulin. I know what the drug does and it's a hypoglycemic drug because it lowers the blood sugar."

  • REALLY ?! Maybe you need to read minimal info about it and only after that to comment ?
MedDx's picture

Yep really... Smile that's what the drug does...I'm surprised someone that is loaded with so much information, like you, wouldn't have known that already...lol!

Take a look if you don't believe me:

http://www.google.nl/url?sa=t&source=web&cd=1&ved=0ahUKEwjep8m7lNPQAhVMW...

MedDx's picture

Excuse me for such short summary on these serious and difficult questions, but this subject is to big for one article.

Post the links and references, then... Smile

CRAZY DOSER's picture