+ 11 Anastrozole or Arimidex, You are not doing it right
Here is another AI that I see people are also not dosing correctly, our good friend Adex or arimidex or anastrozole. I have been researching this inhibitor too to find my sweet spot and stop paying for every visit to my doc for bloodwork. As you will see from these ACTUAL studies, anastrozole is a DAILY dose not eod or every 3 days and it DOES NOT CRUSH YOUR ESTROGEN!!!! It limits free estrogen in your blood only by 20%. Please read these articles and find out for yourself that you MUST dose it daily for it to do anything and there is not worry about crashing your estro UNLESS what you are taking is not pharmacy grade. As we all know you could be dosing ANYTHING or your ugl is over/underdosed. Never use research or ugl ai's only use pharmacy. This is the 1st article that is VERY important to FULLY read and please read the entire article not just what you want to hear.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143915/
From reading that article, you will also notice that Letrozole is not that bad either, i.e it does not crash estrogen levels. You will also see that obese or overweight men will have a higher E2 level and lower testosterone and that is why it is preached by most that you must lose weight to increase test levels before hopping on a cycle of any kind. Here is another important read
http://www.medscape.com/viewarticle/586804_4
Here is a quick excerpt:
Aromatase inhibition also modestly decreased E2 (approximately 20%), though the mean remained in the normal range. Additionally, anastrozole therapy increased bioavailable testosterone, DHT and LH as compared to placebo. These increases in androgen levels and the associated mild decrease in E2, however, failed to significantly improve body composition or strength. Importantly, anastrozole therapy did not alter PSA levels, urinary obstructive symptoms, or lipid profiles.
http://elitemensguide.com/anastrozole-arimidex-for-men-on-testosterone-t...
Here is another interesting find, Anastrozole is to be used at either .25 EVERY DAY or .5 EVERY OTHER DAY. If you do .25 eod you are once again keeping your estrogen levels the same with no change, those that are doing .5 every other day are the ones that saw a change.
So once again please read the medical articles and stop using parrots who never even got a blood test but they say they "felt" a change. You cannot go by feel you have to go by bloodwork. Swith up and use PHARMACY Anastrozole at .25 every day or .5 every other day and watch how everything works right.
OR you can trust some guy on the internet who could be a 12 year old girl tell you something else and you can follow that. Stay safe.
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Also ... how long does it take for arimidex to start "working"
A little longer then what it would take for you to do a little research and find the answer yourself.
Well well seems like someone has a mouth on them , do you talk to your momma like that
Testrogen_PropC...Come on bro he didn't even say anything offensive. I know for me it starts working almost immediately after i take it. But will probably take a week or so to reach its stabilized level because of its 46 hr half life. Meaning it starts working day one, but day 3 you'll have more of it in your body than you did on day 1 etc
I'm done with these guys. Let them do what they are going to do. Some people can't help themselves. He's only been trying to figure it out since June.
https://www.eroids.com/forum/steroids-qa/pct-anti-estrogens/arimdiex-dos...
Testrogen_PropC...I feel it bro. I'm sure I will reach that point sometime soon too. Since I've only been "super active" on eroids for 2 or 3 weeks, I still have a little patience left for the lazy's. Lol
I'm sure another month or 2 I'll prob reach the "fuck it" point. One thing is for damn sure tho, between the big bulk cycle thread and the oz guy the idiots are out in full force today
:)...lol
So I used arimidex .25mg every day and I'm getting very dry skin around my eye brows , would this be associated to high estro or low ? Only reason I ask is because I feel better with taking arimidex everyday and having this dryness but if I stop taking it I still get dryness around my eye brows possibly from oily skin ?
unreal89Very good read! Thanks
Testrogen_PropC...+1 Mack and completely agreed. After experimenting every way possible my best dose currently is .25 every day. When I was doing EOD I'd feel and random twinge or 2 in my nips on the off days so I just find it more stable this way.
And I have a rant in mind to type out about this but I'll save the drama for my mama, or something like that. Lol
noob941great post brother,
Interesting read. My first experience with adex was an interesting one. I accidentally overdosed it for the 1st week. Instead of taking .25 eod I took about 8x that. Well I learned really fast what crashing your e2 feels like. After that I have been pretty well in balance.
I now use pharmacy only ai's. I prefer stane. I don't need anything on trt levels of test. On cycle I've found that I don't aromatize that much. I've gotten away with as little as 6 mg of stane eod works fine for me. Bloods always come back good.
I have a friend who is the same way. He gets sensitive nips and that's it. Y'all are lucky..
lol
Lol... Itchy nips and crying to any soft rock music is my warning buzzer e2 is creeping up. To low and my joints start to snap, crackle and pop and I feel emotionally shut down.
Managing E2 isn't easy...lol
Thumbs up!! Nice work and great post for further clarification regarding Adex administration. So, there's no way that Adex will crash your estrogen?
Not according to the medical posts, it seems it just suppresses it to a certain degree. I nees to find out more so Im still digging by how muc. One study says 20%, another 70%. But all seem to agree that it will not crash it.
Makes sense, since it doesn't destroy like exemestane...I ran an aromasin PCT (12.5/12.5/6.25/6.25) after a high dose multi-compound cycle, and E2 was 27 six weeks after. However, I can say that my knee joints felt weak going up and down stairs, during the PCT. Thanks, bro..
I can say from first hand experience either too much of the drug or too low of e2 can make you feel terrible. I'd lean towards the latter. We throw around the term "crashed" as if e2 is zero. Where in reality it's most likely very very low..
Testrogen_PropC...Very good point brother. That's part of what my rant that i didnt post was about. I think the term crashed is used too loosely, and I think Arimidex doseage "crashing estro" is gravely over exaggerated by some. (Not referring to anybody in this thread guys, y'all are awesome)
X2...
So, start Adex in a cycle the first, or second week, on eod regimen, then get bloodwork beginning week 5?
That would depend on your past bloods and how you reacted. On a general consensus I would dose ed at 1st for 7 days then get bloods drawn and see where you are at. You could need to dial it back or you might need to increase it.
Perfect...thank you, sir!! ;)
Great info here Mack! Thanks for posting this up. I typically need .5 to 1mg eod on 800mgs of test, to keep my estro right around the 40 to 42 range according to blood work. Listening to fucking bro science years ago is what gave me my pea size lump that'll flare up from time to time. Oh well lesson learned. +1 buddy
Adex .5mg eod always worked best for me...never really got bloods. Instead I just matched "my feel" to my more consistent use of asin
I have got more bloods on asin and I dialed that in at 12.5mg 2x/day ED and for lighter compound use 12.5mg spilt ED, so 6.25mg
So I am in the right(bloods) and in the wrong here LOL...with "my feel"
Nice post man!
I stop in very infrequent but I saw this and had to chime in
And afterthought (of course)...THIS^^ works for me. It may not for everyone else. This took about 2-3 yrs of blood tests
X2
Shit gets expensive!
Yes. There needs to be a much more inexpensive way to test E2...like using a DM monitor for diabetes...they need to make one for E2...
You are doing it right lol. You dialed in your bloods to match. "Feel" is more geared towards the inexperienced , Its taken me over 2 years to know when something isnt right or when its working.
It takes a LONG time...see it was years for you too. Plus "the feel" is very subtle and it only comes from experience. If someone has about 2-3 yrs of cycles under their belt, that's just the beginning. Tack on another several years before it's "dialed in" and then you know MIGHT know what "the feel" is you are looking fit without bloods
Good post and articles. I must say that my previous cycle I ran arimidex at .25 mg eod beginning week 5. Brought Estro values from 180ish down to 40 verified by bloodtest week 7 if I remember right.
Point being, dont rely solely on broscience, or studies. Test yourself because we all respond differently.
Exactly, nothing is plug and play and why bloods are essential for correct dial in. You respond to .25 eod where I have to take .50 eod for anything to work.
So true. Every body reacts differently. Bloods are truly the best way to find a sweet spot+1
It seems like the men in that last study were predisposed to having a high estrogen conversion even with trt doses so the higher amounts of adex and daily dosing were warranted. Have to take into account the study group, these individuals receiving it did not have so called "normal" conversion rates. I would have to think that so called "normal" estro conversion rate men would have experienced low estro symptoms from crashing it at those doses. All I know is that what works for me is .25mg of adex E3.5D with 500mg of test and I need to bump it up to .25mg EOD when my test hits 750mg/wk. That dose keeps me in the "zone" and feeling great.
Replying so you get the new link without the period
The bigger picture is you get bloods taken which is the most important piece, which is why I say that. The studies done were in predisposition but still cover a basic. In replacement therapy .25 a day and .5 every other is now starting to be the norm for only a theuraputic dose and as we get into higher numbers from cycling it does need to dialed in. This post was and is only to make others aware of how and why and even the importance of bloodwork.
Without properly dosing your AI your cycle is basically screwed. Definitely need bloodwork to really dial it in. Actually multiple bloodwork is necessary to dial that in because even slight changes in test dose can have a big impact on how your estro responds. It is even more than changing test doses, adding in other compounds, even if they don't aromatize can have a big impact on your estro levels. Case in point, .25mg adex E3.5d for when my test is around 500. So I was doing 400mg of test with 500mg of 1TC (DHB). I actually had to increase my AI up to .25 EOD (which would be my dose for 750mg of test)even though I was below 500mg of test. The 1-TC was getting to the receptors first and leaving more test floating around that was now aromatizing. A lot of shit goes on when stacking compounds and just another reason bloodwork is necessary and you shouldn't be stacking compounds until you have all of this figured out.
Again, thanks for posting. It's nice to see someone doing sn actual research and posting it for discussion instead of just repeating bro science
Im taking a break from helping single users and trying to help everyone. Its a bigger pool and I know it will help some versus one who wont listen. There wilk be more to come as I dig up more of my research.
Much appreciated brother