Great post! This is good for people to know. L-Arginine is good stuff. I take L-Citrulline and L-Arginine both.

Reason being that supplemental citrulline also assists in nitric oxide production by boosting blood levels of arginine. It's more readily absorbed and bioavailable than arginine alone, and it bypasses metabolism in the liver and gastrointestinal tract and is readily absorbed in the kidneys.

In the first study to show that oral supplementation with citrulline raises blood levels of arginine, 20 healthy volunteers were given 6 different dosing regimens of placebo, citrulline, and arginine.

After one week of oral supplementation, the citrulline dose increased plasma arginine concentration more effectively than arginine alone.

Another study also showed the citrulline supplementation’s “time release” effect on arginine production. In this study an oral dose of 3.8 grams of citrulline resulted in a 227% peak increase in plasma arginine levels after 4 hours, compared with a 90% peak increase with the same dose of arginine.

Thus, acute oral administration of citrulline appears to be considerably more efficient at raising plasma levels of arginine over the long term than arginine itself. Like I said, I take them both, arginine/akg and citruline malate, to be exact.

Arginine was also used for ED before Viagra was invented due to the enhanced blood flow via the vasodilation signaled by the resultant nitric oxide. Ha ha, how's that for a cumbersome sentence?

+1