jasm87's picture
jasm87
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Do steroids (other than testosterone e/g dbol, tren and the others) increase the number of androgen receptors in the body...

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or do they just latch onto the receptors available already?

This question has bothered myself for a while and hopefully we can answer it.

If anybody can provide medical studies, please feel free to.

Thanks.

j223's picture

Steroids are ligands to our receptors. So whether you are using testosterone, tren, boldenone, dianabol or any other steroid, any of them can activate the receptor.

jasm87's picture

That's not what I meant, I know that - I asked if that they could upregulate the receptors - increase number of the AR. Thanks anyway bro.

j223's picture

when receptors are occupied - by any steroid, the body will begin to synthesize more so yes.

jasm87's picture

Thanks for the reply my man, it's appreciated. I've had some great answers from this thread from a few guys - so this is a big thanks to everyone who gave a decent reply. There is always something new to learn in the world of AAS and the human body, we all want to learn as much as we can - helping each other is the way forward.

Doss's picture

Tricky question and answer: yes and no

AAS compounds do not directly increase the number of receptors, and the body does not respond to rising or elevated serum levels by producing more receptors.

Rather these receptors are present and part of the various tissues within the body. Anabolics play a role in producing more tissues with the proper stimulus and nutrients. This increase in tissues subsequently increases the number of receptors in the body.

If the body responded to elevated androgen levels by "producing additional androgen receptors" then the homeostatic binding of enzymes and globulin would not occur. These reactions take place as the body's attempt and restoring homeostasis (balance), and it happens in response to the respective degree of receptor saturation.

jasm87's picture

Thanks Dossier for your input, very informative as usual and definately something to think about.

Doss's picture

You bet

gatorbits's picture

YES!

Proven science!
That's why the Test vs Tren fight: is a semi lie!

Yes its true that until your body produces more androgen sites the Tren molecule will attach and leave extra test floating around for a period of time which can lead to excess E!

This means more sides this leads to the development of less test more Tren less sides, guess what!
Less gains too!

Toward your Q!

Like other pharmacological drugs and the way the body makes changes to accept them; AAS is just the same!
The body will notice an INCREASE in serum androgen molecules and then will start to build new androgen receptors to To accommodate the extra exogenous testosterone or Other testosterone steroid derivatives such as any other AAS!

Gator

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Doss's picture

Another example proving that this is not a bodybuilding forum.

jasm87's picture

Awesome brother, very much appreciated. I'm sending you a FR if thats cool, I would like to discuss this topic further. Thanks again.

TheFlash85's picture

interesting/ great/ contraversial post !!! good read

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jasm87's picture

You make a good point brother, AAS training and 'diet' all go together, I always eat the right amount of cholesterol, whether its from eggs, beef and I have no problems in my bloodwork, LDL, HDL are fine. I have good receptors, I'm not in need of more etc, I asked only because I remember a study claiming that testosterone increased receptors after administation so I wondered if that was the case for the other deriatives/analougues of test and the likes. Zinc wouldn't help anymore than a decent diet, I get plenty of that from meat, it's for those who are deficient that need it. I wouldn't be on trt otherwise lol. Each to his own, nonetheless, we are all different and some things help others better. Thanks.

ScripthookV's picture

I do not believe that they do. My logic is the fact that we are genetically given a certain amount of receptor sites, and as with everybody that varies from person to person. In other words, that's why some people can make 35 lb gains in one 12 week cycle on testosterone, whilst some can only make 10-15.

That's partially what I think.

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jasm87's picture

That is a good point, bro. I know of a study that proved testosterone can increase receptors but have found nothing yet for the other deriatives etc. In theory the others should but perhaps its only due to testosterone being native to the human species/mammals that it can multiply receptors. Back to what you stated, genetics play a role. I guess that some people may have over active receptors or like you stated were given 'a certain amount of receptor sites', both could play a role in how much we respond.

Big_Al's picture

don't need steroids to increase them, normal training does the same thing. plus a Zinc supplement will increase them (and testosterone levels and other benefits)

just google your question its simply answered.

jasm87's picture

I wasn't asking that my man, I asked if other AAS instead of testosterone cause any increase. All that natural shit does fuck all. Zinc lol, Thanks for the reply though anyway. I am on trt btw mate, not some young fool looking to get big quick, I know a fair bit about AAS but there is always a question that needs to be answered in the realm of AAS. Check out my trt posts.

jasm87's picture

Anyone there?