It looks like you both have quite a bit of research to do before your wife takes any type of "tool" to assist in weight loss. I don't recommend Clen at all for NEWBs. The pros use clen to cut down for competition meaning they are already at body fat percentages that are in the single digits. Your wife needs to go to the gym with a good training plan and clean diet to start with. HGH is something that you take for years it isn't a "quick" fix for problems that she has with weight. As far as her "taking" protein several times a day well what does that mean and how does it fit with a clean diet and exercise.. I can take protein but if I eat jelly donuts every day and coco puff for breakfast then the protein is wasted. What I reallly think because I have seen you post this very same question twice before is that you want someone to tell you a quick way out. Well, I am sorry to say there is no quick easy fix. So instead of wasting time looking for one go back to the gym hit the cardio, do some circuit training and clean up the diet. As for taking Tamoxifin, it is a drug that suppresses estrogen and it would a might quick way for her to have nice rebound and gain a lot of fat and water weight should she take it and stop.