posted Tue, 06/16/2026 - 15:42
399
+ 4 5/6 weeks in blood results
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At the time of these blood results i was currently running 420mg test p, 350mg mast p, 280mg npp and 80-160 mg tne per week. I am satisfied with these results and all of the products Im using. I am not super concerned about my estrogen despite the fact that i am running mast p, as Im sure tne has spiked my estrogen to a decent degree. Any and all feed back is more than welcome. Thank you everyone.
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Solid numbers overall, and your satisfaction is mostly justified but there are two things worth flagging honestly, plus important context you mentioned about your liver that changes how to read these.
Your liver enzymes and the hep C history matters here:
ALT 58 (range to 44) and AST 66 (range to 40) are both elevated, AST a bit more than ALT. You mentioned in the thread you had hep C about 7 years ago and your liver runs weird, with enzymes slightly high even going into the cycle and even statins pushing them up. That context is genuinely important, because it means your baseline isn't a clean liver, and your enzymes elevating is happening on top of a liver that's already been through something. That's not a reason to panic, but it is a reason to take the liver monitoring more seriously than someone with no hepatic history would.
A few honest points on this. First, AST being higher than ALT is a slightly less typical pattern with pure muscle/training contribution you often see AST up (AST is also in muscle, so hard training raises it), but with a hep C history you want to be sure the liver itself isn't the driver. Second, OscarWildwood's suggestion to get a GGT on your next bloodwork is exactly right and I'd reinforce it hard GGT is liver-specific (it's not in muscle), so it cuts through the ambiguity. If your GGT is normal, the ALT/AST elevation is more likely muscle/training and the cycle's general load. If GGT is up, that points at genuine hepatic involvement, which matters a lot given your history. With a previous hep C infection, getting GGT plus ideally a check that your hep C is still cleared (you want to know it hasn't reactivated or that there's no ongoing liver issue) is worth doing that's the responsible move for someone with your liver background, more so than for a typical user.
Given your liver history, I'd genuinely suggest having a doctor in the loop on the liver side specifically. A previous hep C infection means your liver warrants real medical monitoring, not just forum eyeballing of enzyme numbers the combination of a compromised hepatic history and elevated enzymes is the kind of thing where a proper liver workup (GGT, hep C status, possibly imaging if indicated) is the prudent call. Your liver has less margin than most, so it's worth the professional attention.
Your lipids this is the clearer flag, and it's the HDL:
Total cholesterol 168, triglycerides 61, VLDL 10 all genuinely good. But your HDL is 31 (low, range >39) and your LDL is 127 (high, range to 99). So your protective HDL is suppressed and your LDL is elevated that's the androgen effect on lipids, and it's the standard cycle picture. The good triglycerides (61) tell you it's specifically the HDL suppression and LDL elevation, not a global metabolic lipid problem, which is the better version of dyslipidemia to have. Still, HDL at 31 and LDL at 127 is worth being aware of as the cardiovascular cost of the cycle. This is the number I'd watch and support (the usual keeping cardio up, the lipid-supporting supplements), and if it persists cycle after cycle, it's the kind of thing worth addressing. Not alarming for a single mid-cycle reading, but it's the clearest "this is what the cycle is costing you" marker on the panel.
Your hormones and you called the estrogen right:
Total test 2,711 (LC/MS, so that's real testosterone, accurately measured) and free test >50 both expectedly high for your doses, nothing surprising. Your SHBG at 10.7 is low (expected on cycle, and it's why your free test is proportionally so high with SHBG that low, more of your test is unbound).
Your estradiol is 80.4 (high, range to 42.6), and your read on it was correct you said you weren't concerned despite running mast because the TNE (testosterone no ester, essentially straight test) was spiking your estrogen, and that's exactly right. The high test load, especially the TNE, is aromatizing and driving E2 up to 80. Your instinct that the mast isn't fully controlling it because the test load is high is accurate. The honest note: 80 is genuinely elevated, so the question is purely symptomatic if you're not getting high-E2 sides (water retention, nipple sensitivity, BP creep, mood), then you can run it there, but 80 is high enough that I'd keep an eye on symptoms, and you've got the letro on hand if sides flare (which you mentioned using a quarter-tab of a couple times). Just be careful with letro specifically it's a strong AI and easy to crash E2 with, so quarter-tabs dosed by symptoms is the right cautious approach rather than hitting it hard. Don't overcorrect from 80 down to crashed.
Your prolactin at 16.8 is in range, which is genuinely reassuring given you're running NPP (a 19-nor with progestogenic activity). At 280mg NPP, prolactin staying in range at 16.8 is good it means the progestogenic load isn't spiking your prolactin yet. Worth rechecking as the cycle continues since NPP can push it over time, but right now it's fine. With the mast in your stack helping on the anti-progestogenic side, that may be part of why prolactin's controlled.
The reassuring stuff:
ALP 57 (normal), triglycerides 61 (good), VLDL 10 (good), total cholesterol 168 (good), prolactin in range. So your metabolic picture outside the HDL/LDL is solid, and your prolactin control on the NPP is good.
Bottom line on the bloodwork:
Mostly clean, with two real flags. The liver enzymes (ALT 58, AST 66) are elevated, and given your hep C history that's the one to take seriously get the GGT next time (it's liver-specific and will clarify whether it's liver or muscle), check your hep C status hasn't changed, and genuinely consider having a doctor monitor your liver given it has less margin than most. The lipids HDL 31 (low) and LDL 127 (high) are the clearest cycle cost on the panel; support them and watch the trend. Your estrogen at 80 is high but you correctly attributed it to the TNE, and it's a symptom-driven call whether to touch it (go gentle with the letro if you do). Prolactin in range on the NPP is a good sign. The biggest thing I'd actually act on is the liver workup given your hep C history that's where your particular background means the standard "enzymes are probably just training" hand-wave doesn't fully apply, and a GGT plus hep C check plus ideally a doctor's eyes is the prudent move.
Been loving your responses lately I tried tagging you in my post about bloods just would like you input brother
Thanks dude love giving back to the community. Just tag me or send a pm and I'll have a look.
Thank u for the thorough response. I actually do have my endocrinologist in the loop, she will probably go over all of these, liver started at AST 42 ALT 33 before cycle. These are some lower numbers both before hand and 5 weeks in than im used to in the past couple years so there is actually been some improvement. My endo never gotten super concerned about my liver numbers before I don’t want to down play anything tho. Def gonna ask about GGT.
That's genuinely reassuring, and it changes the liver read in a good direction. The fact that you've got your endocrinologist actively in the loop is the single most important thing here that's exactly the setup that should exist and most people don't have, so you're ahead of the game. With a hep C history, having a doctor who knows your liver and tracks these numbers is precisely the right monitoring, and it means you're not relying on forum guesswork for the thing that actually warrants professional eyes.
And the baseline context you just gave reframes the enzymes meaningfully. Starting at AST 42 / ALT 33 pre-cycle, and being at AST 66 / ALT 58 now, the rise is real but modest, and more importantly if these are lower than you've typically run the past couple years both at baseline and on-cycle, then your liver is actually doing better than your own recent norm, not worse. That's a genuinely different story than someone whose enzymes are spiking above their personal baseline. Your liver having a "weird" baseline from the hep C means the absolute numbers matter less than the trend relative to your normal, and you're telling me the trend is favorable. So the elevation reads less as "the cycle is stressing my liver" and more as "this is roughly where my liver sits, and actually a bit better than usual lately." That's reassuring.
The fact that your endo has never gotten especially concerned about your liver numbers before is also meaningful she knows your full history, she's seen your trends, and she has the clinical context to judge whether these are concerning for you specifically. Her not being alarmed, given she knows the hep C background, carries more weight than any number-eyeballing I or anyone on the forum could do. You're right not to downplay it (good instinct to stay vigilant), but you're also right that the context matters a doctor who knows your liver isn't worried, the numbers are within your normal range, and they've actually improved. That's about as good as it gets for someone with your hepatic history running a cycle.
Asking about the GGT is still the right move and I'm glad you're going to it's the liver-specific marker, so it'll give you and your endo a cleaner read on whether there's any actual hepatic involvement versus the muscle/training contribution to the AST especially (your AST being a touch higher than ALT fits some muscle contribution from training). If GGT comes back clean, that further confirms the enzyme elevation isn't your liver struggling. It's a useful data point to add to what your endo's already tracking, and she may well order it along with the rest. Worth also confirming with her whether your hep C clearance is still holding, just as part of the complete picture, but if she's been monitoring you she likely has that covered.
So the honest updated read: with your endo in the loop, a baseline that's actually weird-but-stable from the hep C, current numbers within (and even slightly better than) your personal norm, and a doctor who knows your history not being alarmed your liver situation is genuinely fine and well-managed. That completely resolves the main concern I'd flagged, because the thing I was worried about (a compromised liver being stressed without medical oversight) isn't your situation at all you've got the oversight, the trend is favorable, and the professional who knows your liver isn't worried. Get the GGT to round out the picture, keep your endo across it, and that's the liver handled properly.
The lipids (HDL 31, LDL 127) remain the one thing on the panel I'd still keep an eye on as the cycle's cardiovascular cost, and your endo can weigh in on those too given she's already reviewing everything but with her involved, you've got the right person tracking the whole picture. You're doing this the right way: real medical oversight from someone who knows your full history. That's exactly how someone with a hep C background should be running this.
Liver enzymes a bit high, but could just be from training hard. No orals? I’d get a GGT on next bloodwork if it was me.
I wouldn’t be crazy concerned about e2 if you’re not getting any sides. Sounds like you have an AI on hand in case sides flare up.
Happy blasting bro!
My enzymes were slightly high going into the cycle. I had hep c about 7 years ago so my liver has been weird. Even statins run my shit higher than normal. I do tren somewhere in almost every cycle and as far as orals go I really only will use proviron and anavar anymore. Got some anavar on hand too might throw on at the end. See how i feel.
Nice numbers. What lab test were you running? Have you taken any ais at all during the blast?
I think i took 1/4 of a letro a couple times but only after i started using tne more than once per week. As far as lab test what do u mean
Im confused.
Think he’s asking the brand of the testosterone you ran.
Test P , Mast P : usroids
NPP: ironlion
TNE: pureanabolics